DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Art2 and PRMT3

DIOPT Version :9

Sequence 1:	NP_001285600.1	Gene:	Art2 / 33631	FlyBaseID:	FBgn0031592	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_187835.2	Gene:	PRMT3 / 820407	AraportID:	AT3G12270	Length:	601	Species:	Arabidopsis thaliana

Alignment Length:	348	Identity:	119/348 - (34%)
Similarity:	179/348 - (51%)	Gaps:	50/348 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEELAKDDEKMDGNHT-----DANQIIKDRRRQEEHYFKLYGRIEIHEWLLKDSVRIKAYREAIQ 61
            |::.:.||..::|...     |...:.::.|:..|:||..|....||..:|.|.||.:|||:|:.
plant   209 LKQSSADDLIVNGKDAEPKVCDGRLVNRNIRKVNENYFGSYSSFGIHREMLSDKVRTEAYRDALL 273

  Fly    62 HN-EFFRHKTVLDVGCGMGVLSMFAAKAGSKRVLAVEA-------ATISEFAQQVVQDNEFGRVI 118
            .| .......|:|||||.|:||:||||||:.||:||||       ||......:|..|||...|:
plant   274 KNPTLLNGSVVMDVGCGTGILSLFAAKAGASRVVAVEASEKMAKVATKIAKDNKVFNDNEHNGVL 338

  Fly   119 QVIQGKVEDIELPDGIK--KVDIIVCDWMGSCLFSGNMLESLLFARDKWLSATGHIYPDTAQLYL 181
            :|....||:::....|:  .||::|.:|||.||...:||.|:|:|||:||...|.|.||||.:::
plant   339 EVAHSMVEELDKSIQIQPHSVDVLVSEWMGYCLLYESMLSSVLYARDRWLKPGGAILPDTATMFV 403

  Fly   182 AAIKGRDQDLGFWHDVHGFDLSAIRRRCESKA----VVEHVTGDQMMSRVCLVKSLDLYT----- 237
            |........|.||.||:|||:|:|.:......    :|:.:....::::..|:::.||.|
plant   404 AGFGKGATSLPFWEDVYGFDMSSIGKEIHDDTTRLPIVDVIAERDLVTQPTLLQTFDLATMKPDE 468

  Fly   238 ---------EPRQS-AKSRSLFELKVSRNGWVHGLVAYFDVGFS----KSTQRISFSTSPSAPWT 288
                     ||.:| ||:|           ..||:|.:||.||:    |....: .||||..|.|
plant   469 VDFTATATLEPTESEAKTR-----------LCHGVVLWFDTGFTSRFCKENPTV-LSTSPYTPPT 521

  Fly   289 HWNQTVFYLETPLPVRAGECIKG 311
            ||.||:...:.|:.|.....:.|
plant   522 HWAQTILTFQEPISVAPASVLSG 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art2	NP_001285600.1	AdoMet_MTases	70..>150	CDD:100107	39/88 (44%)
PRMT3	NP_187835.2	zf-C2H2_2	57..>112	CDD:403839
		AdoMet_MTases	232..>330	CDD:418430	40/97 (41%)
		Methyltransf_25	284..392	CDD:404528	49/107 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820