DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art2 and prmt2

DIOPT Version :9

Sequence 1:	NP_001285600.1	Gene:	Art2 / 33631	FlyBaseID:	FBgn0031592	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_012826019.1	Gene:	prmt2 / 780163	XenbaseID:	XB-GENE-980934	Length:	634	Species:	Xenopus tropicalis

Alignment Length:	339	Identity:	110/339 - (32%)
Similarity:	185/339 - (54%)	Gaps:	31/339 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 QEEHYFKLYGRIEIHEWLLKDSVRIKAYREAIQHN-EFFRHKTVLDVGCGMGVLSMFAAK-AGSK 91
            |:|.|:..|..:::|..:|.|..|..||:|.|..| .....|.:||:|||.|::|.|.|| |..:
Frog   302 QDEEYYGSYKTLKLHLEMLSDVPRTTAYKEVILRNSSSLCGKHILDLGCGTGIISFFCAKLAQPE 366

  Fly    92 RVLAVEAATISEFAQQVVQDNEFGRVIQVIQGKVEDIELPDGIKKVDIIVCDWMGSCLFSGNMLE 156
            .|.||||:.|:|..:::|:.|....::.||:.:.|:::||   .||||:|.:|||:||....|||
Frog   367 AVYAVEASEIAEQTRRLVKQNGISNLVHVIRQRAEELQLP---TKVDILVSEWMGTCLLFEFMLE 428

  Fly   157 SLLFARDKWLSATGHIYPDTAQLYL---AAIKGRDQDLGFWHDVHGFDLSAIR----RRCESKAV 214
            |:|.|||:||...|.::|.||.::|   :|.|.....:.||.:.:..|.|.::    :...::..
Frog   429 SVLQARDRWLKEDGVMWPSTACIHLVPCSASKEYANKVLFWDNPYQLDFSLLKPLAAKEFFARPK 493

  Fly   215 VEHV-TGDQMMSRVCLVKSLDLYT-EPRQSAKSRSLFELKVSRNGWVHGLVAYFDVGFSKSTQ-- 275
            .::| ..:..:|..|::..|:|.| :..:..:..|.|...|..:|.:||..|:|.|.|....:
Frog   494 PDYVLQPEDCLSEPCILLHLNLKTLQLAELERMNSDFTFFVHTDGLLHGFTAWFSVQFQNLEEQG 558

  Fly   276 RISFSTSPSAPWTHWNQTVFYLETPLPVRAGECIKGVLTMKPSEDSIFDTEFDIFVNFDGREKSV 340
            ::..:|.|.:|.|||..|:|.|:.||.|:.|:.|.|.:..:  .:|::           .|..||
Frog   559 QLELNTGPFSPLTHWKHTLFMLDEPLQVQKGDKISGSVVFQ--RNSVW-----------RRHMSV 610

  Fly   341 TIHQSFVLSDPLTL 354
            |:  |:|::..||:
Frog   611 TL--SWVINGKLTM 622

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art2	NP_001285600.1	AdoMet_MTases	70..>150	CDD:100107	34/80 (43%)
prmt2	XP_012826019.1	2A1904	<22..>232	CDD:273344
		SH3	235..287	CDD:388381
		Methyltransf_25	345..442	CDD:379312	45/99 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D840669at2759
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920