DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art2 and Prmt3

DIOPT Version :9

Sequence 1:	NP_001285600.1	Gene:	Art2 / 33631	FlyBaseID:	FBgn0031592	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_598501.1	Gene:	Prmt3 / 71974	MGIID:	1919224	Length:	528	Species:	Mus musculus

Alignment Length:	322	Identity:	125/322 - (38%)
Similarity:	195/322 - (60%)	Gaps:	11/322 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 LEELAKD-DEKMDGNHTDANQIIKDRRRQEEH-YFKLYGRIEIHEWLLKDSVRIKAYREAIQHN- 63
            :::.|:| ...:|.....:...|.|.:..|:. ||..||...|||.:|||.||.::||:.|..|
Mouse   184 MKQFAQDFVMNVDVRTCSSTTTIADLQEDEDGVYFSSYGHYGIHEEMLKDKVRTESYRDFIYQNP 248

  Fly    64 EFFRHKTVLDVGCGMGVLSMFAAKAGSKRVLAVEAATISEFAQQVVQDNEFGRVIQVIQGKVEDI 128
            ..|:.|.|||||||.|:|||||||.|:|:|:||:.:.|...|..:::.|:....|.:|:||:|::
Mouse   249 HIFKDKVVLDVGCGTGILSMFAAKVGAKKVIAVDQSEILYQAMDIIRLNKLEDTIVLIKGKIEEV 313

  Fly   129 ELPDGIKKVDIIVCDWMGSCLFSGNMLESLLFARDKWLSATGHIYPDTAQLYLAAI----KGRDQ 189
            .||  ::|||:|:.:|||..|...:||:|:|:|:.|:|:..|.:|||...:.|.|:    |..|:
Mouse   314 SLP--VEKVDVIISEWMGYFLLFESMLDSVLYAKSKYLAKGGSVYPDICTISLVAVSDVSKHADR 376

  Fly   190 DLGFWHDVHGFDLSAIRRRCESKAVVEHVTGDQMMSRVCLVKSLDLYTEPRQSAKSRSLFELKVS 254
             :.||.||:||::|.:::....:||||.|....::|..|.:|.:|.:|......:..|.|.|:.:
Mouse   377 -IAFWDDVYGFNMSCMKKAVIPEAVVEVVDHKTLISDPCDIKHIDCHTTSISDLEFSSDFTLRTT 440

  Fly   255 RNGWVHGLVAYFDVGFSKST-QRISFSTSPSAPWTHWNQTVFYLETPLPVRAGECIKGVLTM 315
            :......:..|||:.|.|:. .|:.|||.|.:..|||.||||.||.|.||:|||.:||.:|:
Mouse   441 KTAMCTAVAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFPVKAGEALKGKITV 502

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art2	NP_001285600.1	AdoMet_MTases	70..>150	CDD:100107	37/79 (47%)
Prmt3	NP_598501.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..43
		zf-C2H2_2	48..>97	CDD:289522
		AdoMet_MTases	256..356	CDD:100107	46/101 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D432852at33208
OrthoFinder	1	1.000	-	-		FOG0000206
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820