Protein Alignment Art2 and PRMT8

DIOPT Version :10

• Sequence 1: NP_608821.1
• Gene: Art2 / 33631
• FlyBaseID: FBgn0031592
• Length: 355
• Species: Drosophila melanogaster
• Sequence 2: NP_062828.3
• Gene: PRMT8 / 56341
• HGNCID: 5188
• Length: 394
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 139/317 - (43%)
• Similarity: 215/317 - (67%)
• Gaps: 8/317 - (2%)

  Fly    31 EHYFKLYGRIEIHEWLLKDSVRIKAYREAIQHNE-FFRHKTVLDVGCGMGVLSMFAAKAGSKRVL 94
            ::||..|....|||.:|||.||...||.::.||: .|:.|.|||||.|.|:|||||||||:|:|.
Human    74 DYYFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAKKVF 138

  Fly    95 AVEAATISEFAQQVVQDNEFGRVIQVIQGKVEDIELPDGIKKVDIIVCDWMGSCLFSGNMLESLL 159
            .:|.::||::::::::.|....:|.:.:||||::|||  ::|||||:.:|||.|||..:||.:::
Human   139 GIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELP--VEKVDIIISEWMGYCLFYESMLNTVI 201

  Fly   160 FARDKWLSATGHIYPDTAQLYLAAIKGR---DQDLGFWHDVHGFDLSAIRRRCESKAVVEHVTGD 221
            |||||||...|.::||.|.||:.||:.|   |..:.:|.:|:|||::.||.....:.:|:.|...
Human   202 FARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAMKEPLVDIVDPK 266

  Fly   222 QMMSRVCLVKSLDLYTEPRQSAKSRSLFELKVSRNGWVHGLVAYFDVGFSKSTQRISFSTSPSAP 286
            |:::..||:|.:|:||...:.....|.|.|::.||.:||.||.||::.|:|..:::.|||:|.||
Human   267 QVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEFTKCHKKMGFSTAPDAP 331

  Fly   287 WTHWNQTVFYLETPLPVRAGECIKGVLTMKPSEDSIFDTEFDIFVNFDGR--EKSVT 341
            :|||.|||||||..|.||.||.|.|.::|||:..::.|.:|.:.::|.|:  |.||:
Human   332 YTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTVDLDFKGQLCETSVS 388

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Art2	NP_608821.1	COG4076	39..>204	CDD:443253	79/168 (47%)
PRMT8	NP_062828.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	16..40
		SH3-binding 1. /evidence=ECO:0000269|PubMed:17925405	29..42
		SH3-binding 2. /evidence=ECO:0000269|PubMed:17925405	53..58
		COG4076	86..>259	CDD:443253	80/174 (46%)