DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art2 and alkbh8

DIOPT Version :9

Sequence 1:	NP_001285600.1	Gene:	Art2 / 33631	FlyBaseID:	FBgn0031592	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	XP_009290865.1	Gene:	alkbh8 / 556362	ZFINID:	ZDB-GENE-100922-251	Length:	666	Species:	Danio rerio

Alignment Length:	323	Identity:	67/323 - (20%)
Similarity:	97/323 - (30%)	Gaps:	112/323 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 RRRQEEHYFKLYGRIEIHEWLLKDSVRIKAYREAIQHNEF------FRHKTVLDVGCGMGV---- 80
            ||.:||.  ||..|            :|||....::|.:.      .:|..|.:.|.|.||
Zfish     8 RRTKEEK--KLLRR------------QIKASHTLLKHEDITTVSHPTKHLVVSNGGLGNGVSRES 58

  Fly    81 ------------------------LSMFAAKAGSKRVLAVEAATISEFAQQVVQDNEFGRVIQVI 121
                                    :|..:.:||......:...|:.  .|.......|..|::|.
Zfish    59 LLEVLKEGGTVESLLTPPSKPYAFVSYSSIEAGQNAYTLLNGRTLQ--CQDQTMTLYFSYVVKVD 121

  Fly   122 QGKVEDIELPDGIKKVDIIVCDWMGSCLFSGNMLE---SLLFARDKWLSATGHIYPDTAQLYLAA 183
            ..:.....||.|:..::..|            .||   .:|.|.| |   |.|....|||..|..
Zfish   122 CDRSVSCALPPGLSVLEDFV------------SLEEELQILKAVD-W---TPHADDVTAQKALKH 170

  Fly   184 IKGRDQDLGFWHDVHGFD------------LSAIRRRC-------------------ESKAVVEH 217
            .:.:.....|.:|.:..|            ..|:.:||                   ..:.:..|
Zfish   171 RRVKHYGYEFRYDNNNVDKDKPLPGGLPVECDALLQRCLAGGHISVLPDQLTVNQYQSGQGIPPH 235

  Fly   218 VTGDQMMSRVCLVKSLDLYT-------EPRQSA---KSRSLFELK-VSRNGWVHGLV-AYFDV 268
            |..........|..||...|       :.|..|   ..|||..:| .||..|.||:. ..|||
Zfish   236 VDTHSPFEDTILSLSLGAKTVMDFKHPDGRSVAVVLPERSLLVMKGESRYLWTHGITPRKFDV 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art2	NP_001285600.1	AdoMet_MTases	70..>150	CDD:100107	17/107 (16%)
alkbh8	XP_009290865.1	RRM_ALKBH8	40..119	CDD:240877	13/80 (16%)
		2OG-FeII_Oxy	130..300	CDD:304390	42/185 (23%)
		Methyltransf_11	409..498	CDD:285453
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900