DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Art2 and Alkbh8

DIOPT Version :9

Sequence 1:	NP_001285600.1	Gene:	Art2 / 33631	FlyBaseID:	FBgn0031592	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_001178838.1	Gene:	Alkbh8 / 366783	RGDID:	1304687	Length:	664	Species:	Rattus norvegicus

Alignment Length:	379	Identity:	68/379 - (17%)
Similarity:	108/379 - (28%)	Gaps:	159/379 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 QEEHYFKLYGRIEIHEWLLKDS--VRIKAYREAIQHNEFFRHKTVLDVGCGMGVLSMFAAKAGSK 91
            :::|...:|..|..|....:.|  .||..:.:|:.....     |.|:|||.|      ...|..
  Rat   371 EQKHVHHVYDEIASHFSSTRHSPWPRIVEFLKALPSGSI-----VADIGCGNG------KYLGIN 424

  Fly    92 RVLAVEAATISEFAQQVVQDNEFGRVIQVIQGKVEDIELPDGIKKVDIIVCDWM------GSC-- 148
            :.|.:.....|.....:.::.:|                       ..:|||.:      |||
  Rat   425 KELYMIGCDRSRNLVDICRERQF-----------------------QALVCDALAVPVRSGSCDA 466

  Fly   149 --------------------------LFSGNMLESLLFARDKWLSATGHIYPDTAQLYLAAIKGR 187
                                      |.||.  ::|::.   |  |....|.|....||...:..
  Rat   467 CISIAVIHHFATAERRVEALQEIARLLRSGG--QALIYV---W--AMEQEYRDQKSKYLKGNRIS 524

  Fly   188 DQDLGFWHDVHGFDLSAIRRRCESKAVVEHVTGDQMMSRVCLVKSLDLYTEPR---QSAKSRSLF 249
            ..|.|               ...|...:|.:..:||...|.....|.:::...   :..|||.:.
  Rat   525 QGDKG---------------ELNSATSMEQLLVNQMPEGVSEDPGLSVHSSNNTKDEECKSRKVL 574

  Fly   250 ELKVSRNGWVHGLVAYFDVGFSKSTQRISF-STSPSAPWTHWNQTVFYLETPLPVRAGECIKGVL 313
            ..::.    :|             |.|..| |.....|| |                   :||
  Rat   575 NSELP----IH-------------TNRTCFHSQDVLVPW-H-------------------LKG-- 600

  Fly   314 TMKPSEDS---------------IFDTEFDIFVNFDGREKS------VTIHQSF 346
              ||.:|.               :|...:.:|.|.: .|.|      |:|.|||
  Rat   601 --KPGKDKAVEQSGLARCPDPRPVFHRYYHVFCNGE-LEASCQAVGDVSILQSF 651

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Art2	NP_001285600.1	AdoMet_MTases	70..>150	CDD:100107	16/113 (14%)
Alkbh8	NP_001178838.1	DUF1891	1..37	CDD:117570
		RRM_ALKBH8	42..122	CDD:240877
		2OG-FeII_Oxy	152..334	CDD:304390
		Methyltransf_11	412..501	CDD:285453	18/119 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0500
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900