DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3702 and Clptm1l

DIOPT Version :9

Sequence 1:	NP_001260017.1	Gene:	CG3702 / 33628	FlyBaseID:	FBgn0031590	Length:	641	Species:	Drosophila melanogaster
Sequence 2:	NP_001101710.1	Gene:	Clptm1l / 316916	RGDID:	1307896	Length:	539	Species:	Rattus norvegicus

Alignment Length:	578	Identity:	203/578 - (35%)
Similarity:	308/578 - (53%)	Gaps:	85/578 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 SLILRALIIYFVSS-------FFRRPAPDAASQGKSVANAGPKITAWNY--------FENGTDFD 102
            ||::...::|.|.:       .:.||....|:..:......||:....|        .||..|..
  Rat    10 SLVVGVFVVYVVHTCWVMYGIVYTRPCSGDANCIQPYLARRPKLQLSVYTTTRSSLGAENNVDLV 74

  Fly   103 LHVWLSENPDVVN-FQQKANLLWLQKDLTYGDWTSGVNGDGIYTHSLKLKTSQHLMNNGSVYLHA 166
            |:|   |:.||.: |::..|:                        |:..||    .|||::|.:.
  Rat    75 LNV---EDFDVESKFERTVNV------------------------SVPKKT----RNNGTLYAYI 108

  Fly   167 FVTRTGMSP--DPKAPNYATKMGHQQHQLNKFKKLRVNR--NYNLLASE---KEKLEHELKHANL 224
            |:...|:.|  |          |.|.|.::......:.:  ..|||..|   ::::|.|.|.:|.
  Rat   109 FLHHAGILPWHD----------GKQVHLVSPLTTYMIPKPEEINLLTGESATQQQIEAERKPSNA 163

  Fly   225 KDTIVSHWHPNLTVNLVVDQTNWAEGSVPPPLDDYVKFVDGGKT--YLPILFVNDYWNLQREYQP 287
            .|..||||.|.||:|::||...:...|:|..:..|:|.:..|||  ||||||::...|..::...
  Rat   164 LDEPVSHWRPRLTLNVMVDDFVFDGSSLPADVHRYMKMIQLGKTVHYLPILFIDQLSNRVKDLMV 228

  Fly   288 INETTPELELHLTFQPLGMFKWQLYAAKQMKNKWAGNMLGELMAASQPEESDEDQDSLKETLLDT 352
            ||.:|.||.|.:::..:.:.:.:.:.          :|...:.:..|...|::|.|.:|...:||
  Rat   229 INRSTTELPLTVSYDKISLGRLRFWI----------HMQDAVYSLQQFGFSEKDADEVKGIFVDT 283

  Fly   353 NIYLLGITVAVSILHSVFELLAFKNDIQFWNNRKSLEGLSVRSVFFGVFQSLIILLYVLDNETNF 417
            |:|||.:|..|:..|.:|:.|||||||.||..:||:.|:|.::|.:..|.:::|.|::||.:|:.
  Rat   284 NLYLLALTFFVAAFHLLFDFLAFKNDISFWKKKKSMIGMSTKAVLWRCFSTVVIFLFLLDEQTSL 348

  Fly   418 MIRISCFVGLGIEVWKIHKVVDINYDHDQKILGVLPRISFQDKGSYSES--STKDYDKLAFKYLG 480
            ::.|...||..||:||:.|.:.:....    .||.|...|   |::|||  .|:.||..|.|||.
  Rat   349 LVLIPAGVGAAIELWKVKKALKMTVTW----RGVRPVFQF---GTHSESERKTEKYDAQAMKYLS 406

  Fly   481 WACFPLLVAYFVYSLIYNEHKGWYSFVLNMLYGYLLTFGFILMTPQLFINYKLKSVAHMPWRMMT 545
            :..:||.|...||||:..::|.|||:::|.....:..|||:.|.||||:|||:|||||:||:..|
  Rat   407 YLLYPLCVGGAVYSLLNIKYKSWYSWLINSFVNGVYAFGFLFMLPQLFVNYKMKSVAHLPWKAFT 471

  Fly   546 YKFLNTFIDDIFAFVIKMPTMYRLGCFRDDIIFFVFLYQRWQYRVDLKRVNEFGFSGE 603
            ||..||||||:|||:|.|||.:||.|||||::|.|:|||||.|.||..||||||.|.|
  Rat   472 YKAFNTFIDDVFAFIITMPTSHRLACFRDDVVFLVYLYQRWLYPVDKSRVNEFGESYE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3702	NP_001260017.1	CLPTM1	55..496	CDD:283294	136/467 (29%)
Clptm1l	NP_001101710.1	CLPTM1	22..423	CDD:398952	135/458 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2489
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1106937at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100901
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.720