Protein Alignment CG3702 and CLPTM1

DIOPT Version :10

• Sequence 1: NP_608819.1
• Gene: CG3702 / 33628
• FlyBaseID: FBgn0031590
• Length: 641
• Species: Drosophila melanogaster
• Sequence 2: NP_001285.1
• Gene: CLPTM1 / 1209
• HGNCID: 2087
• Length: 669
• Species: Homo sapiens
• Alignment Length: 685
• Identity: 342/685 - (49%)
• Similarity: 448/685 - (65%)
• Gaps: 65/685 - (9%)

  Fly     4 AGEDQPAAEGAVIAGNG--------NAELAQNEGQNEQQQPPPNQPTRMESFFAMTKSLILRALI 60
            |.::...|..||:|..|        |..:.::.....|.|.||.||.  .:.:.:.|.::.|..|
Human     3 AAQEADGARSAVVAAGGGSSGQVTSNGSIGRDPPAETQPQNPPAQPA--PNAWQVIKGVLFRIFI 65

  Fly    61 IYFVSSFFRR-PAP-DAASQGKSVANAGPKITAWNYFENGTDFDLHVWLSENPDVVNFQQKANLL 123
            |:.:||:||| ||| |.|..|     ..|::.:.|.|...|..:|||::||:....:|...:.|.
Human    66 IWAISSWFRRGPAPQDQAGPG-----GAPRVASRNLFPKDTLMNLHVYISEHEHFTDFNATSALF 125

  Fly   124 WLQKDLTYGDWTSGVNGDGIYTHSLKLKTSQHLMNNGSVYLHAFVTRTGMSPDPKAPNYATKMG- 187
            |.|.||.|||||||.|.||.|.|..:|...|.:..|||:|:|.:.|::|..|||:......::.
Human   126 WEQHDLVYGDWTSGENSDGCYEHFAELDIPQSVQQNGSIYIHVYFTKSGFHPDPRQKALYRRLAT 190

  Fly   188 -HQQHQLNKFKKLRVNRNYNLLASEKEKLEHELKHANLKD----TIVSHWHPNLTVNLVVDQTNW 247
             |....:||:|:.|..:..|||..|.|.....:|.|  :|    .::||||||:|:|:|.|.|.|
Human   191 VHMSRMINKYKRRRFQKTKNLLTGETEADPEMIKRA--EDYGPVEVISHWHPNITINIVDDHTPW 253

  Fly   248 AEGSVPPPLDDYVKFVDGGKTYLPILFVNDYWNLQREYQPINETTPELELHLTFQPLGMFKWQLY 312
            .:||||||||.||||......|.||::.|||||||::|.||||:...|.|.::|.||.:::||||
Human   254 VKGSVPPPLDQYVKFDAVSGDYYPIIYFNDYWNLQKDYYPINESLASLPLRVSFCPLSLWRWQLY 318

  Fly   313 AAKQMKNKWAGNMLGELMAASQPEESDEDQDSLKETLLDTNIYLLGITVAVSILHSVFELLAFKN 377
            ||:..|:.|  |.||:.:.    |:|||:|||:|..||:||.|||.:|:.|||:|||||.|||||
Human   319 AAQSTKSPW--NFLGDELY----EQSDEEQDSVKVALLETNPYLLALTIIVSIVHSVFEFLAFKN 377

  Fly   378 DIQFWNNRKSLEGLSVRSVFFGVFQSLIILLYVLDNETNFMIRISCFVGLGIEVWKIHKVVDINY 442
            ||||||:|:|||||||||||||||||.::|||:|||||||::::|.|:|:.|::|||.||:|:..
Human   378 DIQFWNSRQSLEGLSVRSVFFGVFQSFVVLLYILDNETNFVVQVSVFIGVLIDLWKITKVMDVRL 442

  Fly   443 DHDQKILGVLPRISFQDKGSYSESSTKDYDKLAFKYLGWACFPLLVAYFVYSLIYNEHKGWYSFV 507
            |.:.::.|:.||:||:||.:|.|||||.||.:||:||.|..||||..|.||||:|.|||||||:|
Human   443 DREHRVAGIFPRLSFKDKSTYIESSTKVYDDMAFRYLSWILFPLLGCYAVYSLLYLEHKGWYSWV 507

  Fly   508 LNMLYGYLLTFGFILMTPQLFINYKLKSVAHMPWRMMTYKFLNTFIDDIFAFVIKMPTMYRLGCF 572
            |:||||:|||||||.||||||||||||||||:||||:|||.|||||||:||||||||.|||:||.
Human   508 LSMLYGFLLTFGFITMTPQLFINYKLKSVAHLPWRMLTYKALNTFIDDLFAFVIKMPVMYRIGCL 572

  Fly   573 RDDIIFFVFLYQRWQYRVDLKRVNEFGFSGEMEQQHAAQKLEGKTANGAI--------------- 622
            |||::||::|||||.||||..||||||.||| :...||...|..||.||:
Human   573 RDDVVFFIYLYQRWIYRVDPTRVNEFGMSGE-DPTAAAPVAEVPTAAGALTPTPAPTTTTATREE 636

  Fly   623 ----------EG------PQAAPAIKKTAAQKKQD 641
                      :|      ||.||  .|.|..||:|
Human   637 ASTSLPTKPTQGASSASEPQEAP--PKPAEDKKKD 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3702	NP_608819.1	CLPTM1	52..497	CDD:461689	225/452 (50%)
CLPTM1	NP_001285.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		13/48 (27%)
		CLPTM1	57..497	CDD:461689	225/452 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	614..669		13/56 (23%)