DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ft and Fat1

DIOPT Version :9

Sequence 1:	NP_477497.1	Gene:	ft / 33627	FlyBaseID:	FBgn0001075	Length:	5147	Species:	Drosophila melanogaster
Sequence 2:	XP_017455748.1	Gene:	Fat1 / 83720	RGDID:	621254	Length:	4624	Species:	Rattus norvegicus

Alignment Length:	4628	Identity:	1174/4628 - (25%)
Similarity:	1871/4628 - (40%)	Gaps:	1178/4628 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 QYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGN----LDRESRGSYQLNISARDGGSPPRFGY 253
            :|:|::|:.:|.|:  ......||..:|.:.|.|.    |:||.|..|.|.|.|.:..:... ..
  Rat    72 RYKIISGDNENLFK--AEEYVLGDFCFLRIRTKGGNTAILNREVRDHYTLVIKAVEKVTDAE-AR 133

  Fly   254 LQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTV 318
            .:|.|.:||.||..|:|..:.|:|||.|.....|.:..|.|:|.|:|.|.:..|...:....|.:
  Rat   134 AKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRTDMFAI 198

  Fly   319 NPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARD-----HGSPRQDGRTYVTVNLLDTNDH 378
            :|.:||:..|.|::..:....:         ..:.|.|     :||........:||::...|:.
  Rat   199 HPTSGVVVLTGRLDVLETQRYE---------LEILAVDRGMKLYGSSGVSSLAKLTVHVEQANEC 254

  Fly   379 DPIISFRFFPDGGKVATVDENAVN-GTVVAAVAVKDSDSGLNGR-TSVRIVSGNELGHFR----L 437
            .|.|:         ..|:..:.:: ....|.:.|:|.|.|.||. .|:.||:|:.|..|:    .
  Rat   255 APEIT---------AVTLSPSELDKDPTYAIITVEDCDQGANGEIASLSIVAGDLLQQFKTVRSF 310

  Fly   438 EEAADLHIVRVNGV-LDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPV-FEKSEYS 500
            ..:....:..|.|| .|....| |||||.|.|:|||.:.:...:|..::......|| ||...|.
  Rat   311 PGSKAFKVKAVGGVDWDSHPYG-YNLTVQAKDKGTPPQFSPVKVIHVISPQFRAGPVKFEMDVYR 374

  Fly   501 AVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTV 565
            |.:||.||..:.|..:.|...    .:.:.|...|......|.::..||||....|:.|:.....
  Rat   375 AEISEFAPPHTPVVLVKAIPS----YSHLRYVFKSTPGKPKFGLNHNTGLISILEPIKRQHTTHF 435

  Fly   566 ELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGT 630
            ||.::..|     :.|.|::.|.::..|...|:|:|.....:..|:||..|.|..::|.|.|:|.
  Rat   436 ELEVTTSD-----RRASTKVVVKVVGTNSNPPEFTQTSYKASFDENAPVGTPVMRVSAVDPDEGE 495

  Fly   631 NGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQ-YEISVIARDQGAPTPQ--SATA 692
            ||.||:::|    .|..:.|.:|..||.::|...||.|.|.: |.:.:.|.|.|.|..:  ...|
  Rat   496 NGYVTYSIA----NLNHVPFVIDHFTGAVSTSENLDYELMPRVYMLRIRASDWGLPYRREVEVLA 556

  Fly   693 TVWLNVADVNDNDPQF--------YPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDN 749
            |:.||  ::|||.|.|        .||           |:.:.:::        .|.|..|..:.
  Rat   557 TITLN--NLNDNTPLFEKTNCEGTIPR-----------DLGVGEQI--------TTVSAIDADEL 600

  Fly   750 ALIEYRLESGGE-GLFQLDARSGAISLRGD------APASMHWKPHYKLLVSARD---------- 797
            .|:.|::|:|.| .||.|:..||.:||:..      |..|.|     .|.::|.|
  Rat   601 QLVRYQIEAGNELDLFGLNPSSGVLSLKHSLMDGLGAKVSFH-----SLRITATDGENFATPLYI 660

  Fly   798 ----AGQR-----RSQQDAIVEIVLKSKLE---MLECGQAQAGGYEFQMVEDHEQQ-RNSQP--- 846
                |..|     |.::..:.:::.:..|:   :...|.|:...::...|..|..| |.|.|
  Rat   661 NLTVAASRKPVNLRCEETGVAKMLAEKLLQANKLHHQGDAEDIFFDSHSVNAHAPQFRGSLPTGI 725

  Fly   847 ----NREVG--IVQVKST------NGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQ 899
                :..||  |:.:.:|      |||    :.|.|..|:....|.:|..:|.:....|||||..
  Rat   726 EVKEDLPVGASILFMNATDLDSGFNGK----LVYAISGGNDDSCFTVDMETGMLKVLSPLDREVT 786

  Fly   900 ANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEI 964
            ..|.|.|..........||..      ::::.::|.|||||.|.   :....:.:.|:..:..||
  Rat   787 DKYTLNITVYDLGIPQRAAWR------LLDVTVLDANDNAPEFL---QESYFVEVSEDKEINSEI 842

  Fly   965 YLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGS--P 1027
            ......|:|.|.:..::|::..: .::|.|..||||:.:.:|:..|...:.::::.|.|..:  |
  Rat   843 IQVEATDKDLGPSGHVTYAILTD-TEKFAIDRVTGVVKIIQPLDREVQRVHYLKIEARDQATEEP 906

  Fly  1028 PLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGN 1092
            .|||.:.|.|.:.||||:.|.|...||...:.|.....|....|.|.|.|:|.:.::.|.::: :
  Rat   907 WLSSTVLLKVSLDDVNDNPPRFIPPSYSVKVREDLPEGTIIMWLEAHDPDVGQSSQVRYSLLD-H 970

  Fly  1093 TERMFGVFP-DGYLFVRAPLDREERDYYALTVSCRDAGQP-SRSSVVPVVIHVIDENDN--APQF 1153
            .|..|.|.. .|.:.:...||.|::..|.|||..:|.|:| |.||...|.:.|:|.|:|  ||.|
  Rat   971 GEGHFDVDKLSGAVRIVQQLDFEKKQLYNLTVRAKDKGKPASLSSTGYVEVEVVDVNENLHAPVF 1035

  Fly  1154 TNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL--SSQTQDFTIDTRNGFIKTLRPFDR 1216
            ::.....::.|:.|..:.|..::|.|.|.||:.|:.:::  .|....|.||...|.|:|....||
  Rat  1036 SSFVEKGTVKEDVPMGSSVMTVSAHDEDTGRDGEIRYSIRDGSGVGVFRIDEETGVIETSDRLDR 1100

  Fly  1217 EALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRA 1281
            |:.                      ::..|....:|.|:..|...::|.:.|.|||||||:....
  Rat  1101 EST----------------------SHYWLTVYATDQGVVPLSSFIEVYIEVEDVNDNAPQTSEP 1143

  Fly  1282 PYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQL-SLGRRLDRES 1345
            .|:..|.|.:.:...:..:...|.|...:..:.|.:..||..|.|::...||.: :..|:||||.
  Rat  1144 VYYPEIMENSPKDVSVVQIEAFDPDSSSSDKLTYRITSGNPQGFFSIHPKTGLITTTSRKLDREQ 1208

  Fly  1346 QEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLE-------TSPTGTEL 1403
            |:.|.|.|...|..:. |.|:.|.:.:.:||||||.|:|.|...::.:.|       .|.....|
  Rat  1209 QDEHILEVTVTDNGVP-PRSTIARVIVKILDENDNRPQFLQKFYKIRLPEREKADGDRSAKREPL 1272

  Fly  1404 MRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSY-TLNITASDCGTP 1467
            .|..|:|.|:|.|:::.:||..||....|.|:..||.:...|   :.....| .|:|.|.|.|.|
  Rat  1273 YRVIAADKDEGPNAELSYSIEEGNEHGRFSIEPKTGVVSSKK---FSAAGEYDILSIKAIDNGRP 1334

  Fly  1468 SLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPI--------VTVTADDPDSGLNGKV 1524
            ..|:|...:                  :..|.:..|...||        .||...||.:.:.|
  Rat  1335 QKSSTTRLH------------------IEWISKPKPSLEPISFEESVFSFTVMESDPVAHMIG-- 1379

  Fly  1525 SYAISKQEPQLP----------------------------QG----RHFGINTETGVIHTLREID 1557
              .||.:.|.:|                            :|    .||.::..||.|...:.:|
  Rat  1380 --VISVEPPGMPLWFDIIGDALAREAFYIFQMTCDLNCTAEGGNYDSHFDVDKGTGTIIVAKPLD 1442

  Fly  1558 RESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSK----- 1617
            .|...::.|||.|||    ....:.|:.|:.||  |.||:.            |:|||||
  Rat  1443 AEQKSSYNLTVEATD----GTSTILTQVLIKVI--DTNDHR------------PQFSTSKYEVSV 1489

  Fly  1618 ----GSSTAVMQVHAKDADSSSNGLVTYEIVSGPQEL--FKLQRNTGIITFTPGPQFKQEVRYQ- 1675
                ...|.::|:.|.|.|..:..:.|.:....|..|  |:|...||.: :| ..:...|..:|
  Rat  1490 PEDTEPETEILQISAVDRDEKNKLIYTLQSSIDPASLKKFRLDPATGAL-YT-SEKLDHEAIHQH 1552

  Fly  1676 -LTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTA- 1738
             ||:...|:.|..:|..:.:.:.:    |..::.| |.|.. |...|.|||:..:|:.:|.|||
  Rat  1553 VLTVMVRDQDVPVKRNFARIIVNV----SDMNDHS-PWFTS-SSYEGRVYESAAVGSVVLQVTAL 1611

  Fly  1739 ---HLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGG 1800
               ...:||:.|.:.:       |.:...|.||..||.:.||.|||| :...:|::.|.|...|.
  Rat  1612 DRDKGRNAEVLYSIES-------GNIGNSFTIDPILGSIKTARELDR-SHQVDYDLMVKATDKGE 1668

  Fly  1801 QPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMDGHD 1865
            .|.:..|.||::|...:::.|:|....:...:||.::||..:..:.||   :..||.:.:.||:.
  Rat  1669 PPMSEMTSVRISVTVADNASPKFTSKEYSAEISEAIRIGSFVGMVSAH---SQSSVMYEVKDGNI 1730

  Fly  1866 G-KFLLEPSTGKLILNDTLDRETKSKYELRIRVSD--GVQYTEAYATIQVSDTNDNPPLFEDTVY 1927
            | .|.:.|.:|.::....||.||...|.|.::.::  |:. |.....:.:.|.|||||.|....|
  Rat  1731 GDAFNINPHSGSIVTQRALDFETLPIYTLTVQGTNMAGLS-TNTTVVVHIQDENDNPPAFTRAEY 1794

  Fly  1928 SFDIPENAQRGYQVGQIV-----------ARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTL 1981
            |..|.|:|    .|..:|           |.|||...||.|.|.:|....::.|:::|.||.:..
  Rat  1795 SGFISESA----SVNSVVLTDKNVPLVIRATDADRESNALLVYQIVEPSVHNYFAIDPTTGAIHT 1855

  Fly  1982 TARLDYEEVQHYILIVQAQDNGQPSL----STTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPI 2042
            ...|||||.:.:...||..|.|.|.|    :..:||:  |:|:||..|:|....|.:.:......
  Rat  1856 VLSLDYEETRVFHFTVQVHDMGTPRLFAEYAANVTVH--VIDINDCPPVFSKSLYEASLLLPTYK 1918

  Fly  2043 ATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID-SNGTIRTRRNLDREHRSTYTLTVTARDC 2106
            ...|:||:|.|.||.....:.||||.|::..:|.:| ..|||..:..  .:.||.|.|||.|.|
  Rat  1919 GVNVITVNATDADSRAFSQLIYSITKGNIGEKFSMDHKTGTIAIQNT--TQLRSRYELTVRASD- 1980

  Fly  2107 ADEFASFSELEETQLKLK--YRSPRKYQQ-----------TRQEFLA------------------ 2140
                ..|:.:...::.:|  ..||.|:.|           |..:.||
  Rat  1981 ----GRFTSVASVRINVKESRESPLKFTQDAYSAVVKENSTEAKTLAVITAIGNPINEPLFYRIL 2041

  Fly  2141 -----------------------HQKQQRLSSTVKVT--------------ILIKDVNDEVPVFI 2168
                                   .::|:.....|:||              :.::|.||..|||:
  Rat  2042 NPDRRFKISHTSGVLSTTGIPFDREQQETFVVVVEVTKEREPSAVAHVVVKVTVEDQNDNAPVFV 2106

  Fly  2169 SANETAIME-NVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRV 2232
            :....|::: :..:..|:..|.|:|.|.||||.:.|.:||..|.         |.:.|: |.:.:
  Rat  2107 NLPYYAVVKVDAEVGHVIRHVTAIDRDSGRNGDVHYYLKEHHDH---------FEIGPS-GDISL 2161

  Fly  2233 VDALDRE-LRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAM 2296
            ....:.: |...||:.:.|:|.|.|..|.|  :|:.|...|...|||:...|||.:.||....:.
  Rat  2162 KKQFEHDTLNKEYLVTVVAKDGGNPAFSAE--VLVPITVMNKAMPVFEKAFYSAEIPENVQTHSP 2224

  Fly  2297 VLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALE 2361
            |:.|.|.. .||.  ::.|||..||....|:|:.:|||:.|...|::|....|.|::||.|
  Rat  2225 VVHVQANS-PEGL--KVFYSITDGDPFSQFTINFNTGVINVIAPLDFESHPAYKLSIRATD---- 2282

  Fly  2362 NPAGDTAELTINIL--DINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRY 2424
            :..|..||:.::|:  |||||.|.|:...|...:.|.:|  .|..:|.|.|.|:|:.| |..:.|
  Rat  2283 SLTGAHAEVFVDIVVEDINDNPPVFVQQSYSTTLSEASV--IGAPILQVRATDSDSEP-NRGISY 2344

  Fly  2425 FLKEGDS---DLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDIND 2486
            .|....|   |.|.|::.:|.|:|::.||.||..::.|.:.|:|.|.|||:...:|.|:|.|:||
  Rat  2345 QLIGNHSKSHDHFHIDSHTGLISLVRALDYEQFQQHKLLVRAVDGGMPPLSSDVVVTVDVTDLND 2409

  Fly  2487 NDPVFELQSYHATV--------------------------------------------------- 2500
            |.|:||.|.|.|.:
  Rat  2410 NPPLFEQQVYEARISEHAAHGHFVMCVKACDADRSDLDRLEYSILSGNDHKSFVIDGETGIITLS 2474

  Fly  2501 ---------------------------------------------------RENLPSGTHVLTPR 2514
                                                               .||.|..|.|:..:
  Rat  2475 NPRRHTLKPFYSLNVSVSDGVFRSSARVNVTVMGGNLHSPVFHQNEYEVELAENAPLHTLVVQVK 2539

  Fly  2515 ATDKDEGLNAKLRFNLLGEH-MHRFHIDSETGEISTATTLDREETS--VYHLTLMAQDSSITEPR 2576
            |||:|.|:...|.::|:.:. ..||:: ::.|::.|...||||..:  |..:.|||:|:.   .:
  Rat  2540 ATDRDSGIYGHLTYHLVNDFAKDRFYV-NDGGQVFTLERLDREAPAEKVISVRLMAKDAG---GK 2600

  Fly  2577 ASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTI---SGR 2638
            .:...:.:.::|.|||.|:|.||.|.|.|....:||..|....|.|.|:|.||.|.|.|   |..
  Rat  2601 VAFCTVNVILTDDNDNAPQFRSTKYEVNVGSSAAKGTSVVKVFASDADEGSNADVTYAIEADSES 2665

  Fly  2639 DQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPEL-FPT 2702
            .:...:||..||:::||..|    ...::..:|..:.|:|.|.....|...:.|.:.|||: .|.
  Rat  2666 VEENLEINQLTGLITTKESL----IGLENEFFTFFVRAVDNGSPPKESVVPVYVKILPPEVQLPR 2726

  Fly  2703 FA---YMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLR-----VDPNSG 2759
            |:   |.    :::|||:..|..|..:.....     |.:.|.:..|...:|.|     :|..||
  Rat  2727 FSEPFYT----YSISEDMPIGTEIDLIRVEHS-----GTVLYTLVKGNTPESNRDEFFVIDRQSG 2782

  Fly  2760 LLSVGQDGLDYELTHLYEIWIEA--ADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEE 2822
            .|.: :..||:|.|..|:..|.|  ...|...:.|:. :::.|.|||||:||:|...|.|.::|.
  Rat  2783 RLKL-EKSLDHETTKWYQFSILARCTLDDYEVVASID-VSIQVKDANDNSPVLESNPYEAFIVEN 2845

  Fly  2823 ESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDG----TFEIT-ESGEIYTRMRLDREEIGDYAFV 2882
            ......:..|:|||.|||.||.|:|.|....|.    :|.|. |:|.|.|...||.||...|...
  Rat  2846 LPAGSRVIQVRASDLDSGVNGQVMYSLDQSQDADIIESFAINMETGWITTLKELDHEERASYQIK 2910

  Fly  2883 VEAVDQGVP-HMTGTASVLLHLLDKNDNPPKFT-RLFSLNVTENAEIGSFVIRVTSSDLDLGANA 2945
            |.|.|.|.. .::.||.|.:.:.|.||:||:|| .::...|:|:...|..:..::::|.| ....
  Rat  2911 VVASDHGEKVQLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPPGGVIAILSTTDAD-SEEI 2974

  Fly  2946 NASYSFSENPGE---KFRIEPQSGN--ITVAGHLDREQQDEYILKVVASDGAWRAETPITITIQD 3005
            |...|:....|:   :|.:|....:  :.|...|||||:|.|:|.|.|:||.:.::..:.:.:.|
  Rat  2975 NRQVSYFITGGDALGQFAVENMQNDWRVYVKKPLDREQKDSYLLTVTATDGTFSSKARVEVKVLD 3039

  Fly  3006 QNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSL-QQPSPMFSIDPATGEV 3069
            .|||:|..|.:.||.:.||......||.|:.|||.|.:. |:.|:|:| ...:..|.::|.|||
  Rat  3040 ANDNSPVCERTAYSDAIPEDALPGKLVMQVSATDADIRS-NAEITYTLFGSGAEKFKLNPDTGE- 3102

  Fly  3070 FSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLP 3134
                                  |..||                 ::|      :.|||.
  Rat  3103 ----------------------LRTLA-----------------LLD------REEQAV------ 3116

  Fly  3135 QDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVV 3199
                                                                        |.|:|
  Rat  3117 ------------------------------------------------------------YHLLV 3121

  Fly  3200 RATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGML 3264
            :|||.|  .:|.:..:|:.:...|.:||.|:.:.|.:.|.||...|:.:..|.|||.|.|.|..:
  Rat  3122 KATDGG--GRSCQATIVLTLEDVNDNTPEFTADPYAITVFENTEPGTPLTRVQATDADAGLNRKI 3184

  Fly  3265 RYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGY-HPLSSVAMLTIILTDVN 3328
            .||:....:.| ||::|::|.:.:::.||.:|...|.|.:...|.|. ..|::...:.:.:.|:|
  Rat  3185 SYSLLDSADGQ-FSINEQSGILQLEKHLDRELQAVYTLTLKAADQGLPRKLTATGTVVVSVLDIN 3248

  Fly  3329 DNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTIS 3393
            ||||||.::||...:.|:..:||.|.|.:||.:|...||.|.||.:
  Rat  3249 DNPPVFEYREYGATVSEDIVIGTEVLQVYAASRDIEANAEITYAII------------------- 3294

  Fly  3394 SAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRV 3458

  Rat  3295 ----------------------------------------------------------------- 3294

  Fly  3459 GAVQATDKDSGEDGRVYYLLVGSSNDKG-FRIDTNTGLIYVARHLDRETQNRVVLTVMAKNYGSI 3522
                                  |.|:.| |.||:.||.|::..:||.|:.:...|||.|.:.|:
  Rat  3295 ----------------------SGNEHGKFSIDSKTGAIFIIENLDYESSHGYYLTVEATDGGT- 3336

  Fly  3523 RGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSII 3586
             .:.:|.|.|.|:|.|.|| .|.|.:..||:.:||.|.:...|.|:.|.|.| ...|:...||||
  Rat  3337 -PSLSDVATVNINITDINDNSPVFSQDSYTTVVSEDAALEQPVITIMADDAD-GPSNSHILYSII 3399

  Fly  3587 NGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTF 3651
            .||....|.||...|||.....||||..|.|.|.:.|.|.|.||:..:.||:|::.|||||.|.|
  Rat  3400 EGNQGSPFTIDPVRGEIKVTKPLDRETISGYTLTVQAADNGNPPRVNTTTVNIDVSDVNDNAPLF 3464

  Fly  3652 TPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFD 3716
            :.:..:..|.||:|.|.|::.|:.:|.|...||.||::.::.|...:...|::: ||:.:..:..
  Rat  3465 SRDNYSVIIQENKPVGFSVLKLVVTDKDSSHNGPPFSFAIVSGNDDNMFEVNQH-GVLLTAATVK 3528

  Fly  3717 REMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIAVSLFNGDLPSNVKLADVR 3781
            |::.......::|.|:|||:..|...:.|.|::::.:|.....|.|.::. :|:..|...:..:.
  Rat  3529 RKVKDHYLLHVKVADNGKPQLSSLTHIDIRVIEESIHPPAILPLEIFITA-SGEEYSGGVIGKIH 3592

  Fly  3782 PNDIDIVGDYRCRLQKNPAQSQLQLAIPRACDLITTS---HTTPIASVFSYTG------------ 3831
            ..|.|:.                        |.:|.|   |...:.||.|..|
  Rat  3593 ATDQDVY------------------------DTLTYSLDPHMDGLFSVSSTGGKLIAHRKLDIGQ 3633

  Fly  3832 -------NDGKHGDVSSKVSVAFQSFNNETLANSVSIMVRNMTAYHFLANHYR------------ 3877
                   .|||...|:. ::|..|....|.|.::::|...|:|...|:.:::|
  Rat  3634 YLLNVSVTDGKFTTVAD-ITVHIQQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRALRNILGI 3697

  Fly  3878 -----PILEMIKSRMSNEDEVILYSLLEGG------------SGNSTNLQLLMAVRL-------- 3917
                 .|:.:..|...:..:|:|:....||            :.:.|:::.::.||:
  Rat  3698 RKNDIQIVSLQPSEPHSHLDVLLFVEKSGGTQISTKQLLHKINSSVTDIEEIIGVRILDVFQKLC 3762

  Fly  3918 --------------------------AKTSYQQPKY----------------------------- 3927
                                      |:.|:..|::
  Rat  3763 AGLDCPWKFCDEKVSVDENIMSTHSTARLSFVTPRHHRTAVCLCKDGTCPPVHQGCEDNPCPAGS 3827

  Fly  3928 ---------------------------------------------------LIERLR-------- 3933
                                                               |..|||
  Rat  3828 ECVADPREEKYSCVCPGGGFAKCPGSSSITFTGSSFVKYRLMENENRLEMKLTMRLRTYSSHAVV 3892

  Fly  3934 ------------------------------------------------EKRSAFSELLQKEV--- 3947
                                                            |....:::|:..||
  Rat  3893 MYARGTDYSILEIHTGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVSLEVEGNYAKLVLDEVHTA 3957

  Fly  3948 ----------------------------------------------------------------- 3947

  Rat  3958 SGTAPGALKTLNLDNYVIFGGHLRQQGTKHGRNTQVANGFRGCMDSIYLNGQELPLNNKPRAYAH 4022

  Fly  3948 ------------IVGYEPCSEPDVCENGGVCSATMRLLDAHSFVIQDSPALVLSGPRVVHDYSCQ 4000
                        :...|.||. :.|:|||||:                       |.....|.|:
  Rat  4023 IEEWVDLAHGCLLTATEDCSS-NPCQNGGVCN-----------------------PSPTGGYYCK 4063

  Fly  4001 CTSGFSGEQCSRRQDPCLPNPCHSQVQCRRLGSDFQCMCPANRDGKHCEKERSDVCYSKPCRNGG 4065
            |::..:|..|....:||..|||.....|......|.|.|.....|:.|  :.|..|..:||:|||
  Rat  4064 CSALHAGTYCEVSVNPCSSNPCLYGGTCMVDNGGFVCQCRGLYTGQRC--QLSPYCKDEPCKNGG 4126

  Fly  4066 SCQRSPDGSSYFCLCRPGFRGNQCESVSDSCRPNPCLHGGLCVSLKPGYKCNCTPGRYGRHCERF 4130
            :|..|.||:  .|.|..||||.:|:|..|.|..|||.:|.||.:....|.|||:....|:|||..
  Rat  4127 TCFDSLDGA--VCQCDSGFRGERCQSDIDECAGNPCRNGALCENTHGSYHCNCSQEYRGKHCEDA 4189

  Fly  4131 SYGFQPLSYMTFP 4143
            :    |..|::.|
  Rat  4190 T----PNHYVSTP 4198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ft	NP_477497.1	Cadherin_repeat	71..152	CDD:206637
		Cadherin_repeat	163..266	CDD:206637	23/76 (30%)
		Cadherin_repeat	275..378	CDD:206637	26/107 (24%)
		Cadherin_repeat	393..490	CDD:206637	30/103 (29%)
		Cadherin_repeat	498..594	CDD:206637	23/95 (24%)
		Cadherin_repeat	603..704	CDD:206637	34/103 (33%)
		Cadherin_repeat	735..814	CDD:206637	24/104 (23%)
		Cadherin	843..>907	CDD:278457	22/78 (28%)
		Cadherin	950..1026	CDD:278457	17/75 (23%)
		Cadherin_repeat	1053..1149	CDD:206637	31/97 (32%)
		Cadherin_repeat	1157..1274	CDD:206637	28/118 (24%)
		Cadherin_repeat	1282..1380	CDD:206637	29/98 (30%)
		Cadherin_repeat	1390..1485	CDD:206637	27/102 (26%)
		Cadherin_repeat	1497..1597	CDD:206637	33/139 (24%)
		Cadherin_repeat	1621..1699	CDD:206637	20/81 (25%)
		Cadherin_repeat	1720..1818	CDD:206637	33/101 (33%)
		Cadherin_repeat	1827..1918	CDD:206637	24/93 (26%)
		Cadherin_repeat	1926..2023	CDD:206637	36/111 (32%)
		Cadherin_repeat	2031..2162	CDD:206637	40/199 (20%)
		Cadherin_repeat	2172..2274	CDD:206637	29/103 (28%)
		Cadherin_repeat	2282..2380	CDD:206637	35/99 (35%)
		Cadherin_repeat	2388..2487	CDD:206637	36/101 (36%)
		Cadherin_repeat	2495..2592	CDD:206637	29/201 (14%)
		Cadherin_repeat	2600..2694	CDD:206637	29/96 (30%)
		Cadherin_repeat	2710..2806	CDD:206637	27/102 (26%)
		Cadherin_repeat	2814..2909	CDD:206637	36/100 (36%)
		Cadherin_repeat	2917..3009	CDD:206637	25/96 (26%)
		Cadherin	3018..3114	CDD:278457	23/96 (24%)
		Cadherin	3129..3220	CDD:278457	9/90 (10%)
		Cadherin_repeat	3233..3330	CDD:206637	29/97 (30%)
		Cadherin_repeat	3338..3434	CDD:206637	15/95 (16%)
		Cadherin_repeat	3443..3541	CDD:206637	23/98 (23%)
		Cadherin_repeat	3550..3647	CDD:206637	41/96 (43%)
		Cadherin_repeat	3657..3753	CDD:206637	26/95 (27%)
		EGF	4017..4047	CDD:278437	9/29 (31%)
		EGF_CA	4056..4090	CDD:238011	16/33 (48%)
		EGF_CA	4094..4128	CDD:238011	14/33 (42%)
		Laminin_G_1	4156..4306	CDD:278483
		LamG	4428..4543	CDD:238058
Fat1	XP_017455748.1	Cadherin_repeat	39..145	CDD:206637	22/75 (29%)
		Cadherin_repeat	154..253	CDD:206637	25/107 (23%)
		Cadherin	278..357	CDD:421759	28/79 (35%)
		Cadherin_repeat	372..>444	CDD:206637	20/80 (25%)
		Cadherin_repeat	468..566	CDD:206637	34/103 (33%)
		Cadherin_repeat	576..663	CDD:206637	24/110 (22%)
		Cadherin_repeat	725..819	CDD:206637	25/103 (24%)
		Cadherin_repeat	827..924	CDD:206637	26/97 (27%)
		Cadherin_repeat	932..1016	CDD:206637	26/84 (31%)
		Cadherin_repeat	1043..1136	CDD:206637	28/114 (25%)
		Cadherin_repeat	1144..1242	CDD:206637	29/98 (30%)
		Cadherin_repeat	1251..1345	CDD:206637	27/114 (24%)
		Cadherin_repeat	1363..1476	CDD:206637	29/122 (24%)
		Cadherin_repeat	1485..1582	CDD:206637	21/102 (21%)
		Cadherin_repeat	1590..1686	CDD:206637	33/103 (32%)
		Cadherin_repeat	1695..1785	CDD:206637	24/93 (26%)
		Cadherin_repeat	1793..1898	CDD:206637	35/110 (32%)
		Cadherin_repeat	1919..1994	CDD:206637	26/81 (32%)
		Cadherin_repeat	2008..2101	CDD:206637	9/92 (10%)
		Cadherin_repeat	2109..2198	CDD:206637	28/100 (28%)
		Cadherin_repeat	2211..2303	CDD:206637	35/98 (36%)
		Cadherin_repeat	2311..2410	CDD:206637	36/101 (36%)
		Cadherin_repeat	2418..2512	CDD:206637	2/93 (2%)
		Cadherin_repeat	2520..2616	CDD:206637	27/99 (27%)
		Cadherin_repeat	2625..2718	CDD:206637	29/96 (30%)
		Cadherin_repeat	2732..2829	CDD:206637	28/107 (26%)
		Cadherin_repeat	2837..2937	CDD:206637	35/99 (35%)
		Cadherin_repeat	2946..3043	CDD:206637	25/97 (26%)
		Cadherin_repeat	3056..3145	CDD:206637	35/203 (17%)
		Cadherin_repeat	3153..3250	CDD:206637	29/97 (30%)
		Cadherin_repeat	3258..3355	CDD:206637	39/204 (19%)
		Cadherin_repeat	3363..3460	CDD:206637	41/97 (42%)
		Cadherin_repeat	3469..3560	CDD:206637	25/91 (27%)
		Cadherin_repeat	3585..3658	CDD:206637	16/97 (16%)
		LamG	3878..4009	CDD:214598	8/130 (6%)
		EGF_CA	4040..4074	CDD:238011	13/57 (23%)
		EGF_CA	4077..4112	CDD:238011	11/36 (31%)
		EGF	4117..4147	CDD:394967	16/31 (52%)
		EGF_CA	4151..4187	CDD:238011	14/35 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1219
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100175
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.710