DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ft and Fat2

DIOPT Version :9

Sequence 1:NP_477497.1 Gene:ft / 33627 FlyBaseID:FBgn0001075 Length:5147 Species:Drosophila melanogaster
Sequence 2:NP_075243.1 Gene:Fat2 / 65048 RGDID:620656 Length:4351 Species:Rattus norvegicus


Alignment Length:4485 Identity:1122/4485 - (25%)
Similarity:1776/4485 - (39%) Gaps:993/4485 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly   193 QYEIVAGNVDNKFRLVTTANPSGDTSYLHLET----TGNLDRESRGSYQLNISARDGGSPPRFGY 253
            :|.|::|:....|:  |..:..|:..:|.:.|    |..|:||.|.||.|.:.|.|  ....|..
  Rat    70 KYRIISGDAAGVFK--TEEHVVGNFCFLRIRTKSSNTALLNREVRDSYTLIVQASD--KSLEFEA 130

  Fly   254 L-QVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFT 317
            | ||.|.|||.||..|:|....|.|:::|.....:|:..|.|:|.|||.|::..|........|.
  Rat   131 LTQVVVHILDQNDLKPLFSPPSYRVTISEDRPLKSPICKVTATDADLGQNAEFYYAFNARSEVFA 195

  Fly   318 VNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTY-----VTVNLLDTND 377
            ::|.:||::...::|..::...:         ..|.|.|......:|..:     :.:.:...:.
  Rat   196 IHPTSGVVTVAGKLNVTRRGKYE---------LQVLAVDRMRKISEGNGFGNLASLVIRVEPVHR 251

  Fly   378 HDPIISFRFF--PDGGK-----VATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHF 435
            ..|.|:....  |:|.:     :.|||.|. :|..|.::.|...|.|...:.......|||    
  Rat   252 KPPAINLVVLNPPEGDEGDIYAIVTVDTNG-SGAEVDSLEVVGGDPGKYFKVLRSYAQGNE---- 311

  Fly   436 RLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPV------- 493
                   .::|.|..:...|....:|:::    |.........|.||..    .|.|.       
  Rat   312 -------FNLVAVRDINWAEHPHGFNISL----QTHSWSRFPPHSIIRA----FHLPSWKLANLR 361

  Fly   494 FEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLD 558
            |||:.|...|||.:|.||.||.:..|   |.: ..:.|.:...:....|.::..||||.||..:|
  Rat   362 FEKAVYRVKLSEFSPPGSRVALVKVT---TAL-PNLRYSLKPSSRNTAFKLNARTGLITTTKLVD 422

  Fly   559 REIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTA 623
            ...::..:|.:....|.     |.|.:.:.|:|.|:.||.|::.....||.|:.||.|.|..:||
  Rat   423 FHEQNQYQLHVKTSLGQ-----ATTTVIIDIVDCNNHAPVFNRSSYEGTLDENIPPGTSVLTVTA 482

  Fly   624 TDHDQGTNGSVTFALA-PSVERLYPLQFALDALTGQLTTRRPLDREKMSQ-YEISVIARDQGAPT 686
            ||.|.|.||.:|:::| |..     :.|::|.|.|.::|.:|:|.|.|.: |...|.|.|.|:|.
  Rat   483 TDQDHGDNGHITYSIAGPKA-----VPFSIDPLLGVISTTKPMDYELMKRIYTFRVRASDWGSPF 542

  Fly   687 PQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNAL 751
            .|....:|.|.:.::|||.|.|         .:.:..:.|:::|...:.::.|:|.|.|:..|  
  Rat   543 RQEKEVSVSLRLKNLNDNQPMF---------EEVNCTVSLRQDVPVGKSIMAVSAIDMDELQN-- 596

  Fly   752 IEYRLESGGE-GLFQLDARSGAISLRGDAPASMHWKPH-YKLLVSARDAGQRRSQQDAIVEIVLK 814
            ::|.:.||.| ..|.|:..||.|||:.........:|. |.|.::|.|.....|.....|.:|  
  Rat   597 LKYEIVSGNEQDYFHLNHFSGVISLKRSFMNLTAVRPTIYSLKITASDGKNYASPTTLKVTVV-- 659

  Fly   815 SKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNF 879
                                         ..|:.||. ||...|.  ..:||...|:|       
  Rat   660 -----------------------------KDPHSEVP-VQCDKTG--VLTHITKTILQ------- 685

  Fly   880 RIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFAL 944
                                               ||...|...|                    
  Rat   686 -----------------------------------SAGLQSQELG-------------------- 695

  Fly   945 DRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRA 1009
              |.|.|                               ||:|                       
  Rat   696 --EEEFT-------------------------------SLSN----------------------- 704

  Fly  1010 EPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVF-DHTSYETSLPETTKVNTRFFALAA 1073
                                          ..:|.|:|.| ||......:.|...:||....|||
  Rat   705 ------------------------------YQINHHSPQFEDHFPQSIDILEQVPINTPLARLAA 739

  Fly  1074 TDIDLGDNGRISYEIIEGNTERMFGV-FPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVV 1137
            ||.|.|.:|::.|.|.:||.|..|.: ...|.|.|.|.||.|...:|.|.|:..|.|.|.:||..
  Rat   740 TDPDTGFHGKLVYVISDGNEEGCFDIELETGLLMVAAALDYETTSFYVLNVTVYDLGTPPKSSWK 804

  Fly  1138 PVVIHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTID 1202
            .:.:.|.|.|||.|:|....:..:|.|:....|.:.:|...|.|...|..:.:||.:.|:.|::.
  Rat   805 LLTVTVKDWNDNPPRFPPGGYQLTISEDTEVGTTIAELKTEDADSEDNRRVRYTLLTPTEKFSLH 869

  Fly  1203 TRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVI 1267
            ...|.:......|||:..:....|||  .|...:|     :.|...|               .:|
  Rat   870 PFTGELVVTGHLDRESESQYILKAEA--RDQPTKG-----HQLFSVT---------------DLI 912

  Fly  1268 VT--DVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDS 1330
            ||  |:|||.|:.:.....:.:.|....||.:|.:...|.|.|..|:|.|.|.: :..|.|.:..
  Rat   913 VTLEDINDNPPQCITEHRRLKVPEDMPLGTVLTFLDASDPDLGPAGEVKYILVE-DAHGTFQVHP 976

  Fly  1331 ATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSN--ASITIVVLDENDN--APEFTQSSSEV 1391
            .||.|||.:.||.|.:..::|...|.|:.  .|||..  ..:.::|:|.|:|  :|.|:....:.
  Rat   977 MTGALSLEKELDFERRAGYNLSFWASDSG--KPLSRRTLCHVEVLVMDVNENLHSPHFSSFVYQG 1039

  Fly  1392 SVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYT 1456
            .|.|.||.||.:|...|.|.|.|::.::.:.:.||...:||.|:..||.|....|||.|....|.
  Rat  1040 QVQENSPAGTPVMVVTAQDDDSGLDGELQYFLRAGTGLETFSINQDTGMLETLAPLDREFTPYYW 1104

  Fly  1457 LNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLN 1521
            |.:.|.|.|:..||......:.|.|.|||.|..........:.|..||.|.::.:.|.||||...
  Rat  1105 LTVLAVDRGSVPLSAVTEVYIEVTDINDNIPSMSRPVFYPSVLEDAPLGTSVLQLEAWDPDSSSQ 1169

  Fly  1522 GKVSYAISKQEPQLPQGRHFG---INTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLST 1583
            ||:::       .|..|.|.|   ::..||::.|.:::|||:.|.:.|.|...|...||.|  ||
  Rat  1170 GKLTF-------NLTSGNHLGHFIVHPFTGLLTTAKQLDRENKDEYVLEVTVQDNGDPSLR--ST 1225

  Fly  1584 EKLVTVIVEDINDNAPVF------VSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYE 1642
            .::|..|: |:|||.|:|      |.::..:.|.       |...|.::.|.|.|...||.|||.
  Rat  1226 SRVVVCIL-DVNDNPPMFSHKLFNVRLSERLSPL-------SPEPVYRLVASDPDEGLNGSVTYS 1282

  Fly  1643 IVSGPQELFKLQRNTGII----TFTPGPQFKQEVRYQ-LTLKSTDEAVQSERRSSEVYITIITPG 1702
            |....:|.|::...||::    ||..|       .|. ||:|:||....:...|..::|..|.. 
  Rat  1283 IEESDEESFRIDPVTGVVSSSSTFAAG-------EYNILTIKATDSGQPALSTSVRLHIEWIPQ- 1339

  Fly  1703 SGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDI 1767
              ...||:|.....|..|.:|.|.:|:...:..::.........:.:       |.|..|..|||
  Rat  1340 --PRPSSIPLSFDESYYSFTVMETDPVNHMVGVISVEGRPGLFWFHI-------SDGDKDMDFDI 1395

  Fly  1768 DAKLGILSTAAELD-REAGPEEYEVEV----YAIALGGQPRTSRTKVRV-TVLDKNDSPPQFLDT 1826
            :...|.:..|..|| |........|||    :.||         |:|.: .:.:.|...||||..
  Rat  1396 EKTTGSIVIARPLDTRRKSSYNLTVEVTDGFHTIA---------TQVHIFMIANINHHRPQFLQD 1451

  Fly  1827 PFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMDGHD----GKFLLEPSTGKLILNDTLDRET 1887
            .:...|.:|...|..:..::|.|.|....:.:.::...|    ..|.|:||:|.|:...||:..:
  Rat  1452 HYEIRVPQDTLPGVELLRVQATDQDHGKGLIYTILSSQDPGSANLFQLDPSSGVLVTVGTLELHS 1516

  Fly  1888 -KSKYELRIRVSD---GVQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARD 1948
             .|::.|.:.|.|   .::....:.||.|.|.|.:.|.|....|..::|:....|.::.|:.|.|
  Rat  1517 GPSQHILTVMVRDQEMPIKRNFVWVTIHVEDGNLHSPHFTQLRYEANVPDTTAPGTELLQVRAVD 1581

  Fly  1949 ADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITV 2013
            ||.|.||::.|..:...::..|:::...|::|:..||.:..:..:.|.|:|:|.|.|.......|
  Rat  1582 ADRGANAEIHYSFLKGNSDGFFNIDSLLGIITVAQRLYHVHLTRHALTVKAEDQGSPRRHDLALV 1646

  Fly  2014 YCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID 2078
            ..:|...:.:||:|....|..|:.|:|||.:.::.:||     |::..:.|.:..|:.||.|.::
  Rat  1647 VIHVHPSDSSAPVFSKDEYFIEIPESVPIGSPILLLSA-----GSSSEVTYELREGNKDSVFSMN 1706

  Fly  2079 S-NGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQ 2142
            | :|.|.|::.||.|...:|.|.:...:.|..|                                
  Rat  1707 SYSGLISTQKRLDHEKVPSYRLRIRGSNMAGVF-------------------------------- 1739

  Fly  2143 KQQRLSSTVKVTILIKDVNDEVPVF--------ISANETAIMENVAI--NTVVIAVKAVDNDEGR 2197
                  :.|...:.|.|.||..|.|        ||  |.|.:.::.:  :...:.|:|.|:|...
  Rat  1740 ------TEVVALVYIIDENDNPPAFGKPTFLGHIS--EAAPLHSLILGEDNSPLVVRASDSDREA 1796

  Fly  2198 NGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEP----PQ 2258
            |..:.|.:.|......       |.::|:.|.|.....||.|....:..||...|:|.|    |:
  Rat  1797 NSLLVYKILEPEALKF-------FKIDPSMGTLTTTSELDFEDTPLFQFNIYVHDQGTPILFAPR 1854

  Fly  2259 STESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQN 2323
            |  ::::|.:.|.||:.|.|..:.|..:|.|....|..:|.|.|.|.|    .|:.|||...:.:
  Rat  1855 S--AKVIIHVRDVNDSPPRFSEQIYEVAVVEPIHPGMGLLTVQAEDND----SRVTYSIKTSNAD 1913

  Fly  2324 HDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSP 2388
            ...:|...||.:.|..........::|  :||.|....    |||.:.|::..:.|....|....
  Rat  1914 EAVTIHPTTGQISVVNPATLRLFQKFS--IRASDGLYH----DTAVVKISLTQVLDKSLQFDQDV 1972

  Fly  2389 YLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALLK----PL 2449
            |.|||.|||.......:|.|:...     ||..:.|||..| :|||.:..|:|   :|:    ..
  Rat  1973 YRARVTENTPHRKALVILGVHGNH-----LNDTLSYFLLNG-TDLFHMIESAG---VLQTRGGTF 2028

  Fly  2450 DREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPR 2514
            |||||..:.:.:...|...|......:|||.|:|:|||.|.|:...|:..:::....|..:....
  Rat  2029 DREQQDTHEVAVEVRDNRVPQRVAQALVRVSVEDVNDNIPEFQHLPYYTVIQDGTEPGDVLFQVS 2093

  Fly  2515 ATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASS 2579
            |||||.|.|..:.:....::.: |.||...|:||.....|.:..:.|||.::|:||.| .|..:.
  Rat  2094 ATDKDLGANGSVTYGFAEDYAY-FRIDPYVGDISLKKPFDYQALNKYHLRVIARDSGI-PPLQTE 2156

  Fly  2580 VNLTISVSDVNDNIPKFDSTTYNVAVPERI----------------------------------- 2609
            |.:.::|.  |.:.|.|.|..|.|.|||.|                                   
  Rat  2157 VEVHVTVR--NKSNPLFQSPYYKVKVPENITLYTPILHTQARSPEGLRLIYNIVEEEPLMLFTTD 2219

  Fly  2610 ---------------SKGEFVFGARALDL------------------------------------ 2623
                           ||.:.||..||.|.                                    
  Rat  2220 FKTGVLTVTGPLDYESKNKHVFTVRATDTALGSFSEATVEVLVEDINDNPPTFSQLVYTTSVSEG 2284

  Fly  2624 ---------------DDGENAVVHYTI--SGRD-QHYFDINTKTGVVSTKLELKTKTKSHDDLTY 2670
                           |.|:|..|.|.|  .|.| ..:|.||..||.:.|..||..:|..|    :
  Rat  2285 SPAQTPVIQLLASDQDSGQNQDVSYQIVEDGSDVSKFFRINGSTGEIFTIQELDYETHQH----F 2345

  Fly  2671 TIVISAMDQGEQSLSSKAELTVIL-----RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATS 2730
            .:.:.|||:|:..|:.:..:.|.:     .||: |....|.||    :||....|.::.||.|..
  Rat  2346 RVKVRAMDKGDPPLTGETLVVVNVSDINDNPPK-FREPQYEAN----VSELATCGHLVLKVQALD 2405

  Fly  2731 PKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTL 2795
            |..|...::.|.|..|.......::..||::|: .:....:|...|.:.:.|:||   ..|:...
  Rat  2406 PDIGDTSRLEYLILSGNQDRHFSINSTSGIISM-FNLCKKQLDSSYNLRVGASDG---VFRATVP 2466

  Fly  2796 ITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDG-TFEI 2859
            :.:|.|:||..:|..:|.:|.||:.|.......:..:.|.|:|||..|.|.|.:.|...| .|.|
  Rat  2467 VYINTTNANKYSPEFQQNVYEAELAENAKVGTKVIELLAIDKDSGPYGTVDYTIINKLAGERFFI 2531

  Fly  2860 TESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRL-FSLNVTE 2923
            ...|:|.|..:||||...:....::.:.:.........:|.:.|.|:|||.|:|... :::::..
  Rat  2532 NPRGQITTLQKLDRENSTERVIAIKVMARDGGGKVAFCTVKIILTDENDNAPQFKASGYTVSIPS 2596

  Fly  2924 NAEIGSFVIRVTSSDLDLGANANASYSF--SENPGEK-FRIEPQSGNITVAGHLDREQQDEYILK 2985
            |....|.:|:|.:.|.|.|.||:.:||.  :|:..|: ..:.|.:|.:.|...|...:.......
  Rat  2597 NVSRDSPIIQVLAYDADEGRNADVTYSVDSTEDLAEEIIEVNPTTGVVKVKESLVGLENRAVDFN 2661

  Fly  2986 VVASDGA---WRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNS 3047
            :.|.||.   |.:..|:.:.:.......|:|....|:||.||.....:.:|.:.|.  ..|.|  
  Rat  2662 IKAQDGGPPHWDSLVPVRLQVVPNEIPLPKFSEPLYTFSAPEDLPEGSEIGSVKAV--AAQDP-- 2722

  Fly  3048 VISYSLQQ-------PSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLA------TDN 3099
             |.|||.|       ...:||:|..||.:..:||:..:.:::       |.:.::|      || 
  Rat  2723 -IIYSLVQGTTPESNSDDVFSLDQDTGVLKVRKAMDHESTKW-------YQIDLMAHCPHEDTD- 2778

  Fly  3100 GKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTN-EMDYSL 3163
                |.|...|:|.:.|.::|.|.||...|.|.|.::...|..:::|.||| ||.|:: ::.|.|
  Rat  2779 ----LVSLVSVSIQVEDVNDNRPVFEADPYKAFLTENMPGGTTVIQVTAND-QDTGSDGQVSYRL 2838

  Fly  3164 MT---FNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQ-SDETRVVIVVTGENM 3224
            ..   .|:..:|:|....||||.::.:.......|...|.|.|.|...| |.:..|.:.:|.||.
  Rat  2839 SVEPGSNIHELFAVDSESGWITTLQELDCETQQTYRFYVVAFDHGQTIQLSSQALVEVSITDEND 2903

  Fly  3225 DTPRFSVNSYQVIVPENEPVGSTILTVGATDDD-TGPNGMLRYSISGGNERQDFSVDERTGG--- 3285
            :.|||:...|:..|.||...|..:.|:...|.| :..|..:...|:.|:....||:.: .|.   
  Rat  2904 NPPRFASEDYRGSVVENNEPGELVATLKTLDADVSDQNRQVTCYITEGDPLGQFSISQ-VGDEWR 2967

  Fly  3286 IVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVG 3350
            |..::.||.:.|.:|.|.:|..|..:.  :||. :.:.:.|:|||.|..:...|...:.|:...|
  Rat  2968 ISSRKTLDREHIAKYLLRVTASDGKFQ--ASVP-VEVFVVDINDNSPQCSQLLYTGKVREDVTPG 3029

  Fly  3351 TFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNP 3415
            .|:.:..|.|.|...||.|.|:.  .||....|.::...|.:::....|.|.:.:|.|..||.: 
  Rat  3030 HFILKVSAIDVDMDTNAQITYSL--HGPGAQEFKLDPHTGELTTLTVLDRERKDVYNLVAKATD- 3091

  Fly  3416 DSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVS--ETSAVGTRVGAVQATDKDSGEDGRVYYLL 3478
            .......|.:.:|:..||:..|:|...  |.||:  :.:.|.|.|..|.|.|.|.|.:.:|.|.|
  Rat  3092 GGGQSCQAEVTLHIEDVNDNAPRFFPS--HCDVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSL 3154

  Fly  3479 VGSS------------------------------------------------------------- 3482
            ..|:                                                             
  Rat  3155 TDSADGQFSIDATSGVIRLEKPLQVRASSAVELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPI 3219

  Fly  3483 -----------------------------------------NDKG-FRIDTNTGLIYVARHLDRE 3505
                                                     |::| ||:|.:||::||...||.|
  Rat  3220 FLNAEHSTQVPEDAPIDMEVLHLATLTRPGSEKTGYHITGGNEQGKFRLDAHTGILYVNGSLDFE 3284

  Fly  3506 TQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKA 3569
            |..:..|::......|  .:.:|...::|::.|.|: .|.|....||..:.|.|.||..:.||.|
  Rat  3285 TNPKYFLSIECSRKSS--SSLSDVTTIVINVTDVNEHHPRFTHDLYTVRVLENAVVGDVILTVSA 3347

  Fly  3570 IDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTGS 3634
            .|.| ...|:..:||::.||....|.|:.:.|::..|..||.|:|.:|:|.:.|.|:|.||....
  Rat  3348 SDDD-GPVNSAITYSLVGGNQLGHFTINPKKGKLQVAKALDWEQTPSYSLRLRATDSGQPPLHED 3411

  Fly  3635 ATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSW 3699
            ..|.:|:.|||||.|.|.....:..:.||.|.|..::.||..|||.|:||.|:.:::..|...|.
  Rat  3412 TEVAVEVVDVNDNPPRFFQLNYSTSVQENSPIGIKVLQLILDDPDSPQNGPPYFFRITEGNTGSV 3476

  Fly  3700 LSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIAV 3764
            ..|..:..:| :..|..::.....:..|||.|||.|...|..|:.:.|.:|:..|.:|..|.|::
  Rat  3477 FRVTPDGWLV-TAASLSKKAREWYQLHIEVSDSGLPPLSSSTLVRVQVTEQSRYPPSTLPLEISI 3540

  Fly  3765 SL----FNGDLPSNVKLADVRPNDIDIVGDYRCRLQKNPAQSQLQLAIPRACDLITTSHTTP--- 3822
            :.    |.|.:...:...|..|.|                               |.:::..   
  Rat  3541 TKGEEEFQGGMIGKIHATDRDPQD-------------------------------TLTYSLEQEG 3574

  Fly  3823 -IASVFSYTGNDGK--------HGDVSSKVSVAFQSFNN-------------ETLANSVSIMVRN 3865
             :...|:...:|||        ||..|..|:|:..:|..             |....:|.:....
  Rat  3575 GLDRYFTVGASDGKIIASQGLPHGRYSFNVTVSDGTFTTTTGVHVHVWHMEPEVPQQAVWLGFHQ 3639

  Fly  3866 MTAYHFLANHYRPILEMIKSRMSNEDEVILYSLLEGGSGNSTNLQLLMAVRLAKTSYQQPKYLIE 3930
            :|....:::|:|.:...:.:.:..:...|..:.|:.....:....||:..|.:.|||.       
  Rat  3640 LTPEELVSDHWRNLQRFLSNLLDVKRANIHLASLQPAEVTAGVDVLLVFERHSGTSYD------- 3697

  Fly  3931 RLREKRSAFSELLQK-EVIVGYE--------PCS----EPDVCEN-------------------- 3962
             |:|..||.:..::: |..||..        ||.    :...|:.                    
  Rat  3698 -LQELASAIAHSVREIEHSVGIRMRSALPVVPCQGQSCQDQTCQETVSLEPRVGPSYSTARLSIL 3761

  Fly  3963 ------GGVCS---ATMRL----------LDAHSFVI----------------QDSPALVLSGPR 3992
                  |..||   .|:|.          |:|.::.|                .::.::.|....
  Rat  3762 TPRHHLGRNCSCNGTTLRFSGQSYVQYRPLEAQNWQIHFYLKTLQPWALLMFTNETASISLKLAN 3826

  Fly  3993 VVHDYSCQCTSGFSGEQCSRRQDPCLPNPCHSQV------------------------QCRRLGS 4033
            ........|..||.|...||.  |......||.:                        :|:.|.:
  Rat  3827 GFSHLEYHCPGGFYGNLSSRY--PVNDGQWHSMLLEERDTSVHLLVDITDNASLVIPEECQGLRT 3889

  Fly  4034 DFQC----MCPANR-----------------DGKHCE---KER-----------------SDVCY 4057
            :.|.    :.|:|.                 :|:..|   :|:                 ...|.
  Rat  3890 ERQLLLGGLVPSNPSSNVSLGFEGCLDAVVVNGERLELLGREKKMEGRLETWALSQCCWPGTACS 3954

  Fly  4058 SKPCRNGGSCQRSPD-GSSYFCLCRPGFRGNQCESVSDSCRPNPCLHGGLCVSLKPGYKCNCTPG 4121
            ..||.|||||  ||. ||.|.|.|.|.|.|..||...::|...||..||.|||...|..||| |.
  Rat  3955 QSPCLNGGSC--SPALGSGYLCRCPPPFSGRNCELGRENCTSAPCQEGGTCVSSPEGTSCNC-PH 4016

  Fly  4122 RY-------------GRHC------ERFSYGFQPLSYMTFPALDVTTNDISIVFATTKPNSLLLY 4167
            .|             |.||      :|..:|.|....:|. ||.:      ::.||.   .||||
  Rat  4017 PYTGDRCEMEARGCSGGHCLITPEIKRGDWGQQEFLVITV-ALPL------VIIATV---GLLLY 4071

  Fly  4168  4167
              Rat  4072  4071

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ftNP_477497.1 Cadherin_repeat 71..152 CDD:206637
Cadherin_repeat 163..266 CDD:206637 27/77 (35%)
Cadherin_repeat 275..378 CDD:206637 21/107 (20%)
Cadherin_repeat 393..490 CDD:206637 20/96 (21%)
Cadherin_repeat 498..594 CDD:206637 26/95 (27%)
Cadherin_repeat 603..704 CDD:206637 37/102 (36%)
Cadherin_repeat 735..814 CDD:206637 24/80 (30%)
Cadherin 843..>907 CDD:278457 10/63 (16%)
Cadherin 950..1026 CDD:278457 4/75 (5%)
Cadherin_repeat 1053..1149 CDD:206637 35/96 (36%)
Cadherin_repeat 1157..1274 CDD:206637 27/118 (23%)
Cadherin_repeat 1282..1380 CDD:206637 30/99 (30%)
Cadherin_repeat 1390..1485 CDD:206637 33/94 (35%)
Cadherin_repeat 1497..1597 CDD:206637 34/102 (33%)
Cadherin_repeat 1621..1699 CDD:206637 25/82 (30%)
Cadherin_repeat 1720..1818 CDD:206637 22/103 (21%)
Cadherin_repeat 1827..1918 CDD:206637 24/98 (24%)
Cadherin_repeat 1926..2023 CDD:206637 25/96 (26%)
Cadherin_repeat 2031..2162 CDD:206637 28/131 (21%)
Cadherin_repeat 2172..2274 CDD:206637 26/107 (24%)
Cadherin_repeat 2282..2380 CDD:206637 25/97 (26%)
Cadherin_repeat 2388..2487 CDD:206637 34/102 (33%)
Cadherin_repeat 2495..2592 CDD:206637 27/96 (28%)
Cadherin_repeat 2600..2694 CDD:206637 37/197 (19%)
Cadherin_repeat 2710..2806 CDD:206637 24/95 (25%)
Cadherin_repeat 2814..2909 CDD:206637 27/95 (28%)
Cadherin_repeat 2917..3009 CDD:206637 22/97 (23%)
Cadherin 3018..3114 CDD:278457 29/108 (27%)
Cadherin 3129..3220 CDD:278457 28/95 (29%)
Cadherin_repeat 3233..3330 CDD:206637 26/100 (26%)
Cadherin_repeat 3338..3434 CDD:206637 24/95 (25%)
Cadherin_repeat 3443..3541 CDD:206637 33/202 (16%)
Cadherin_repeat 3550..3647 CDD:206637 36/96 (38%)
Cadherin_repeat 3657..3753 CDD:206637 29/95 (31%)
EGF 4017..4047 CDD:278437 8/74 (11%)
EGF_CA 4056..4090 CDD:238011 18/34 (53%)
EGF_CA 4094..4128 CDD:238011 17/52 (33%)
Laminin_G_1 4156..4306 CDD:278483 6/12 (50%)
LamG 4428..4543 CDD:238058
Fat2NP_075243.1 Cadherin_repeat 38..143 CDD:206637 26/76 (34%)
Cadherin_repeat 152..249 CDD:206637 21/105 (20%)
Cadherin_repeat 366..454 CDD:206637 27/96 (28%)
Cadherin_repeat 462..560 CDD:206637 37/102 (36%)
Cadherin_repeat 570..661 CDD:206637 26/123 (21%)
Cadherin_repeat 719..816 CDD:206637 35/96 (36%)
Cadherin_repeat 825..921 CDD:206637 27/117 (23%)
Cadherin_repeat 931..1026 CDD:206637 30/97 (31%)
Cadherin_repeat 1036..1133 CDD:206637 33/96 (34%)
Cadherin_repeat 1141..1238 CDD:206637 34/106 (32%)
Cadherin_repeat 1247..1335 CDD:206637 27/101 (27%)
Cadherin_repeat 1354..1444 CDD:206637 23/105 (22%)
Cadherin_repeat 1452..1551 CDD:206637 24/98 (24%)
Cadherin_repeat 1560..1650 CDD:206637 24/89 (27%)
Cadherin_repeat 1664..1754 CDD:206637 29/132 (22%)
Cadherin_repeat 1766..1867 CDD:206637 27/111 (24%)
E_set 1877..1959 CDD:298831 25/91 (27%)
Cadherin_repeat 1972..2066 CDD:206637 34/102 (33%)
Cadherin_repeat 2074..2163 CDD:206637 25/90 (28%)
Cadherin_repeat 2176..2268 CDD:206637 13/91 (14%)
Cadherin_repeat 2276..2375 CDD:206637 24/102 (24%)
Cadherin_repeat 2383..2475 CDD:206637 25/99 (25%)
Cadherin_repeat 2485..2581 CDD:206637 27/95 (28%)
Cadherin_repeat 2590..2683 CDD:206637 22/92 (24%)
Cadherin_repeat 2697..2795 CDD:206637 30/114 (26%)
Cadherin_repeat 2803..2904 CDD:206637 31/101 (31%)
Cadherin_repeat 2913..3009 CDD:206637 26/99 (26%)
Cadherin_repeat 3018..3111 CDD:206637 25/95 (26%)
Cadherin_repeat 3122..3211 CDD:206637 13/88 (15%)
Cadherin_repeat 3226..3319 CDD:206637 19/94 (20%)
Cadherin_repeat 3328..3424 CDD:206637 36/96 (38%)
Cadherin 3433..3524 CDD:278457 27/91 (30%)
Cadherin_repeat 3535..3621 CDD:206637 18/116 (16%)
Laminin_G_2 3802..3923 CDD:280389 15/122 (12%)
EGF_CA 3953..3986 CDD:238011 18/34 (53%)
EGF 3992..4022 CDD:278437 14/30 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 4316..4340
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG1219
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100175
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.710

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