DRSC/TRiP Functional Genomics Resources

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Protein Alignment ft and Pcdhb10

DIOPT Version :10

Sequence 1:NP_477497.1 Gene:ft / 33627 FlyBaseID:FBgn0001075 Length:5147 Species:Drosophila melanogaster
Sequence 2:NP_001108075.1 Gene:Pcdhb10 / 291649 RGDID:1308364 Length:793 Species:Rattus norvegicus


Alignment Length:678 Identity:193/678 - (28%)
Similarity:313/678 - (46%) Gaps:72/678 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    80 GTTVGFIPTK-PKFSYRFNEPPREFTLDPVTGEVKTNVVLDREGMRD-----------HYDLVVL 132
            |..||.:.|: .:..::.|:...:  ||..||    |::|..:..|:           |:.::: 
  Rat    49 GLRVGELATRGARIHHKGNKDLLQ--LDAETG----NLILKEKPDREVLCRATEPCVLHFQIIL- 106

  Fly   133 SSQPTYPIEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIV 197
             ..|....:..:::.|:||::||||:..:.:..||||..||...|.||.|.|:|.|.|  |...|
  Rat   107 -ENPVQFFQTELQLTDINDHAPEFPDRKMLLKISESAQPGTMFPLKAAQDPDIGSNAV--QNYTV 168

  Fly   198 AGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILD 262
            :.|:  .|.::|.:...| ..|..|.....||||.:....|.:.|.|||:|.|.|...|::.::|
  Rat   169 SPNL--HFHVITHSRTDG-RKYPELVLDRALDREEQPELTLTLIALDGGAPSRSGTTTVHIEVVD 230

  Fly   263 VNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYL---AETEHQFTVNPETGV 324
            :|||||.||.|.|.|.:.|.:.....|.||.|.|.|.|.:..:.|.|   .|....|.::...|.
  Rat   231 INDNPPKFDQSLYEVQIPENSPLNALVATVSARDLDAGIHGTVIYSLFQGGELSQPFEIDEVAGE 295

  Fly   325 ISTTERVNCPQQTNVKSSASQKSCVF---TVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRF 386
            |            .:|.:...::..:   .:.|.|.|.  ..|:..|.:.::|.||:.|.::.  
  Rat   296 I------------RLKGTLDFEATPYYNIEIVATDPGG--FSGKCSVAIQVVDVNDNAPKLTI-- 344

  Fly   387 FPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGV 451
               ....:::.|||.. .|||..:|.|.|||.|||....|  .|||.........:.:.:.....
  Rat   345 ---SSLNSSIPENAPE-AVVAVFSVSDPDSGENGRIVCSI--QNELPFLLKPTFENYYTLVTERP 403

  Fly   452 LDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASI 516
            ||||....||:|:...|.|.|..||...:|:.|:|:||:.|.|.::.|:.::.|.......:.:|
  Rat   404 LDRESRADYNITITVSDLGIPRLTTQHTIIVQVSDINDNAPAFNQTSYTLLVRENNSPALHIGTI 468

  Fly   517 TATDEDTGVNAQVHYDILSGNELK-----WFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGP 576
            :|||.|||.||.:.|.:|...:::     ..|::...|.:.....||.|...|.|.|:.|.|.|.
  Rat   469 SATDSDTGANAHISYLLLPLYDMQLALTSLVSINQENGQLFVLRALDYETLQTFEFSVGATDHGS 533

  Fly   577 NPKFAYTQLKVIILDENDEAPQFSQREQNVT------LGEDAPPQTIVALMTATDHDQGTNGSVT 635
            ....:...::|::||:||.||......||.:      |...|.|..:|..:.|.|.|.|.|..::
  Rat   534 PALSSQALVRVVVLDDNDNAPFVLYPLQNASVPCTELLPRAAEPGYLVTKVVAVDCDSGQNAWLS 598

  Fly   636 FALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVAD 700
            |.|..:.|   |..|.:.|..|::.|.|.|....:.::::.::.:|.|   ....:|||.|:|..
  Rat   599 FQLLKATE---PGLFNVWAHNGEVRTTRLLSERDVPKHKLLLVVKDNG---EHQRSATVTLHVLL 657

  Fly   701 VNDNDPQFYPRHYIY--SLADDDDDIKL 726
            |:.....:.|...:.  .:.||:|.:.|
  Rat   658 VDGFSQPYLPLPEVARDPVQDDEDVLTL 685

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ftNP_477497.1 Cadherin_repeat 71..152 CDD:206637 16/83 (19%)
Cadherin_repeat 163..266 CDD:206637 37/102 (36%)
Cadherin_repeat 275..378 CDD:206637 24/108 (22%)
Cadherin_repeat 393..490 CDD:206637 34/96 (35%)
Cadherin_repeat 498..594 CDD:206637 27/100 (27%)
Cadherin_repeat 603..704 CDD:206637 29/106 (27%)
Cadherin_repeat 735..814 CDD:206637
Cadherin 843..>907 CDD:394985
Cadherin 950..1026 CDD:394985
Cadherin_repeat 1053..1149 CDD:206637
Cadherin_repeat 1157..1274 CDD:206637
Cadherin_repeat 1282..1380 CDD:206637
Cadherin_repeat 1390..1485 CDD:206637
Cadherin_repeat 1497..1597 CDD:206637
Cadherin_repeat 1621..1699 CDD:206637
Cadherin_repeat 1720..1818 CDD:206637
Cadherin_repeat 1827..1918 CDD:206637
Cadherin_repeat 1926..2023 CDD:206637
Cadherin_repeat 2031..2162 CDD:206637
Cadherin_repeat 2172..2274 CDD:206637
Cadherin_repeat 2282..2380 CDD:206637
Cadherin_repeat 2388..2487 CDD:206637
Cadherin_repeat 2495..2592 CDD:206637
Cadherin_repeat 2600..2694 CDD:206637
Cadherin_repeat 2710..2806 CDD:206637
Cadherin_repeat 2814..2909 CDD:206637
Cadherin_repeat 2917..3009 CDD:206637
Cadherin 3018..3114 CDD:394985
Cadherin 3129..3220 CDD:394985
Cadherin_repeat 3233..3330 CDD:206637
Cadherin_repeat 3338..3434 CDD:206637
Cadherin_repeat 3443..3541 CDD:206637
Cadherin_repeat 3550..3647 CDD:206637
Cadherin_repeat 3657..3753 CDD:206637
EGF 4017..4047 CDD:394967
EGF_CA 4056..4090 CDD:238011
EGF_CA 4094..4128 CDD:238011
Laminin_G_1 4156..4306 CDD:395008
LamG 4428..4543 CDD:238058
Pcdhb10NP_001108075.1 Cadherin_2 26..108 CDD:462413 13/66 (20%)
Cadherin_repeat 136..234 CDD:206637 37/102 (36%)
Cadherin_repeat 243..338 CDD:206637 24/108 (22%)
Cadherin_repeat 350..442 CDD:206637 34/94 (36%)
Cadherin_repeat 450..552 CDD:206637 28/101 (28%)
Cadherin_repeat 571..659 CDD:206637 26/93 (28%)
Cadherin_C_2 683..765 CDD:465139 1/3 (33%)
Blue background indicates that the domain is not in the aligned region.

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