DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ft and FAT1

DIOPT Version :9

Sequence 1:	NP_477497.1	Gene:	ft / 33627	FlyBaseID:	FBgn0001075	Length:	5147	Species:	Drosophila melanogaster
Sequence 2:	XP_005262891.1	Gene:	FAT1 / 2195	HGNCID:	3595	Length:	4600	Species:	Homo sapiens

Alignment Length:	4489	Identity:	1179/4489 - (26%)
Similarity:	1865/4489 - (41%)	Gaps:	923/4489 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 QYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGN----LDRESRGSYQL---------NISARD 244
            :|:||:|:.:|.|:  ......||..:|.:.|.|.    |:||.:..|.|         |:.||
Human    71 RYKIVSGDSENLFK--AEEYILGDFCFLRIRTKGGNTAILNREVKDHYTLIVKALEKNTNVEAR- 132

  Fly   245 GGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYL 309
                     .:|.|.:||.||..|:|..:.|:|||.|.....|.:..|.|:|.|:|.|.:..|..
Human   133 ---------TKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSF 188

  Fly   310 AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARD-----HGSPRQDGRTYVT 369
            .:....|.::|.:|||..|.|::         ....|.....:.|.|     :||........:|
Human   189 KDRTDMFAIHPTSGVIVLTGRLD---------YLETKLYEMEILAADRGMKLYGSSGISSMAKLT 244

  Fly   370 VNLLDTNDHDPIISFRFFPDGGKVATVDENAVN-GTVVAAVAVKDSDSGLNGR-TSVRIVSGNEL 432
            |::...|:..|:|:         ..|:..:.:: ....|.|.|.|.|.|.||. .|:.||:|:.|
Human   245 VHIEQANECAPVIT---------AVTLSPSELDRDPAYAIVTVDDCDQGANGDIASLSIVAGDLL 300

  Fly   433 GHFR----LEEAADLHIVRVNGV-LDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEP 492
            ..||    ...:.:..:..:.|: .|....| ||||:.|.|:|||.:.::..:|...:......|
Human   301 QQFRTVRSFPGSKEYKVKAIGGIDWDSHPFG-YNLTLQAKDKGTPPQFSSVKVIHVTSPQFKAGP 364

  Fly   493 V-FEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVH--YDILSGNELKWFSMDPLTGLIVTT 554
            | |||..|.|.:||.||..:.|..:.|      :.|..|  |...|......||::..||||...
Human   365 VKFEKDVYRAEISEFAPPNTPVVMVKA------IPAYSHLRYVFKSTPGKAKFSLNYNTGLISIL 423

  Fly   555 GPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVA 619
            .|:.|:.....||.::..|     :.|.|::.|.:|..|...|:|:|........|:.|..|.|.
Human   424 EPVKRQQAAHFELEVTTSD-----RKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTVM 483

  Fly   620 LMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQ-YEISVIARDQG 683
            .::|.|.|:|.||.||:::|    .|..:.||:|..||.::|...||.|.|.: |.:.:.|.|.|
Human   484 SLSAVDPDEGENGYVTYSIA----NLNHVPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWG 544

  Fly   684 APTPQ--SATATVWLNVADVNDNDPQF--------YPRHYIYSLADDDDDIKLKKEVEKERILLH 738
            .|..:  ...||:.||  ::|||.|.|        .||           |:.:.:::
Human   545 LPYRREVEVLATITLN--NLNDNTPLFEKINCEGTIPR-----------DLGVGEQI-------- 588

  Fly   739 VTASDKDDGDNALIEYRLESGGE-GLFQLDARSGAISLRGD------APASMHWKPHYKLLVSAR 796
            .|.|..|..:..|::|::|:|.| ..|.|:..||.:||:..      |..|.|     .|.::|.
Human   589 TTVSAIDADELQLVQYQIEAGNELDFFSLNPNSGVLSLKRSLMDGLGAKVSFH-----SLRITAT 648

  Fly   797 DAGQRRSQQDAIVEIVLKSKLEMLEC----------------------GQAQAGGYEFQMVEDH- 838
            |.....:.....:.:....||..|:|                      |:.:...::...|..|
Human   649 DGENFATPLYINITVAASHKLVNLQCEETGVAKMLAEKLLQANKLHNQGEVEDIFFDSHSVNAHI 713

  Fly   839 EQQRNSQP-------NREVG--IVQVKST------NGKANSHIEYDIIQGDRAQNFRIDTRSGRI 888
            .|.|::.|       |:.||  ::.:.||      |||    :.|.:..|:....|.||..:|.:
Human   714 PQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGK----LVYAVSGGNEDSCFMIDMETGML 774

  Fly   889 TTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTIS 953
            ....|||||....|.|.|..........||..      ::::.::|.|||.|.|.   :....:.
Human   775 KILSPLDRETTDKYTLNITVYDLGIPQKAAWR------LLHVVVVDANDNPPEFL---QESYFVE 830

  Fly   954 LPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVE 1018
            :.|:..|..||......|:|.|.|..::||:..: ...|.|..||||:.:.||:..|......::
Human   831 VSEDKEVHSEIIQVEATDKDLGPNGHVTYSIVTD-TDTFSIDSVTGVVNIARPLDRELQHEHSLK 894

  Fly  1019 LMATDAG--SPPLSSKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDN 1081
            :.|.|..  .|.|.|.:.:.|.:.||||:.|.|...:|...:.|.....|....|.|.|.|||.:
Human   895 IEARDQAREEPQLFSTVVVKVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQS 959

  Fly  1082 GRISYEII---EGN--TERMFGVFPDGYLFVRAPLDREERDYYALTVSCRDAGQP-SRSSVVPVV 1140
            |::.|.::   |||  .:::     .|.:.:...||.|::..|.|||..:|.|:| |.||...|.
Human   960 GQVRYSLLDHGEGNFDVDKL-----SGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVE 1019

  Fly  1141 IHVIDENDN--APQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL--SSQTQDFTI 1201
            :.|:|.|:|  .|.|::.....::.|:||..:.|..::|.|.|..|:.|:.:::  .|....|.|
Human  1020 VEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDARRDGEIRYSIRDGSGVGVFKI 1084

  Fly  1202 DTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKV 1266
            ....|.|:|....|||:.                      ::..|....:|.|:..|...:::.:
Human  1085 GEETGVIETSDRLDREST----------------------SHYWLTVFATDQGVVPLSSFIEIYI 1127

  Fly  1267 IVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSA 1331
            .|.|||||||:.....|:..|.|.:.:...:..:...|.|...|..:.|.:..||..|.|::...
Human  1128 EVEDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPK 1192

  Fly  1332 TGQL-SLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLE 1395
            ||.: :..|:||||.|:.|.|.|...|.. ..|.|:.|.:.:.:||||||.|:|.|...::.:.|
Human  1193 TGLITTTSRKLDREQQDEHILEVTVTDNG-SPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPE 1256

  Fly  1396 TSPTGTE-------LMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITG---SLYLHKPLDYE 1450
            ......|       |....|:|.|:|.|:::.:||..||....|.|:..||   |.......:|:
Human  1257 REKPDRERNARREPLYHVIATDKDEGPNAEISYSIEDGNEHGKFFIEPKTGVVSSKRFSAAGEYD 1321

  Fly  1451 DITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPI------- 1508
                 .|:|.|.|.|.|..|:|...:                  :..|.:..|...||
Human  1322 -----ILSIKAVDNGRPQKSSTTRLH------------------IEWISKPKPSLEPISFEESFF 1363

  Fly  1509 -VTVTADDPDSGLNGKVSYAISKQEPQLP---------QGRHFGINTETGVIHTLREIDRESIDT 1563
             .||...||.:.:.|    .||.:.|.:|         ...||.::..||.|...:.:|.|....
Human  1364 TFTVMESDPVAHMIG----VISVEPPGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSN 1424

  Fly  1564 FRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHA 1628
            :.|||.|||    ....:.|:..:.||  |.||:.|.|.:....::.|:   .....|.::|:.|
Human  1425 YNLTVEATD----GTTTILTQVFIKVI--DTNDHRPQFSTSKYEVVIPE---DTAPETEILQISA 1480

  Fly  1629 KDADSSSNGLVTYEIVSGPQEL--FKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSERRS 1691
            .|.|..:..:.|.:....|..|  |:|...||.:..:.....:...::.||:...|:.|..:|..
Human  1481 VDQDEKNKLIYTLQSSRDPLSLKKFRLDPATGSLYTSEKLDHEAVHQHTLTVMVRDQDVPVKRNF 1545

  Fly  1692 SEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTA----HLASAEIEYFVTNV 1752
            :.:.:.:     ..:....|.| ..|...|.|||:..:|:.:|.|||    ...:||:.|.:.:
Human  1546 ARIVVNV-----SDTNDHAPWF-TASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIES- 1603

  Fly  1753 TATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKN 1817
                  |.:...|.||..||.:.||.|||| :...||::.|.|...|..|.:..|.||:.|...:
Human  1604 ------GNIGNSFMIDPVLGSIKTAKELDR-SNQAEYDLMVKATDKGSPPMSEITSVRIFVTIAD 1661

  Fly  1818 DSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMDGHDG-KFLLEPSTGKLILND 1881
            ::.|:|....:...:||.:.||..:..:.||   :..||.:.:.||:.| .|.:.|.:|.:|...
Human  1662 NASPKFTSKEYSVELSETVSIGSFVGMVTAH---SQSSVVYEIKDGNTGDAFDINPHSGTIITQK 1723

  Fly  1882 TLDRETKSKYELRIRVSD--GVQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQI 1944
            .||.||...|.|.|:.::  |:. |.....:.:.|.|||.|:|....|:..|.|:|    .:..:
Human  1724 ALDFETLPIYTLIIQGTNMAGLS-TNTTVLVHLQDENDNAPVFMQAEYTGLISESA----SINSV 1783

  Fly  1945 V-----------ARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQ 1998
            |           |.|||...||.|.|.:|....:..|:::..||.:.....|||||...:...||
Human  1784 VLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAIDSSTGAIHTVLSLDYEETSIFHFTVQ 1848

  Fly  1999 AQDNGQPSL----STTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNN 2059
            ..|.|.|.|    :..:||:  |:|:||..|:|....|.:.:........:|:||:|.|.||...
Human  1849 VHDMGTPRLFAEYAANVTVH--VIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAF 1911

  Fly  2060 GLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFS-------ELE 2117
            ..:.||||.|::..:|.:|......|.:| ..:.||.|.|||.|.|  ..||..:       |.:
Human  1912 SQLIYSITEGNIGEKFSMDYKTGALTVQN-TTQLRSRYELTVRASD--GRFAGLTSVKINVKESK 1973

  Fly  2118 ETQLKLK---YRSPRKYQQTRQEFLA--------------------------------------- 2140
            |:.||..   |.:..|...|..|.||
Human  1974 ESHLKFTQDVYSAVVKENSTEAETLAVITAIGNPINEPLFYHILNPDRRFKISRTSGVLSTTGTP 2038

  Fly  2141 --HQKQQRLSSTVKVT--------------ILIKDVNDEVPVFISANETAIME-NVAINTVVIAV 2188
              .::|:.....|:||              ::::|.||..|||::....|::: :..:..|:..|
Human  2039 FDREQQEAFDVVVEVTEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYV 2103

  Fly  2189 KAVDNDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRV-----VDALDRELRSSYLLNI 2248
            .|||.|.||||.:.|.:||..:.         |.:.|. |::.:     :|.|::|    ||:.:
Human  2104 TAVDRDSGRNGEVHYYLKEHHEH---------FQIGPL-GEISLKKQFELDTLNKE----YLVTV 2154

  Fly  2249 TARDRGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRI 2313
            .|:|.|.|..|.|  :::.|...|...|||:...|||.:||:..:.:.|:.|.|.. .||.  ::
Human  2155 VAKDGGNPAFSAE--VIVPITVMNKAMPVFEKPFYSAEIAESIQVHSPVVHVQANS-PEGL--KV 2214

  Fly  2314 RYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINIL--D 2376
            .|||..||....|:|:.:|||:.|...|::|....|.|::||.|    :..|..||:.::|:  |
Human  2215 FYSITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATD----SLTGAHAEVFVDIIVDD 2275

  Fly  2377 INDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDS---DLFRINA 2438
            ||||.|.|....|...:.|.:|  .|..|:.|.|.|:|:.| |..:.|.:....|   |.|.:::
Human  2276 INDNPPVFAQQSYAVTLSEASV--IGTSVVQVRATDSDSEP-NRGISYQMFGNHSKSHDHFHVDS 2337

  Fly  2439 SSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVREN 2503
            |:|.|:||:.||.||..::|:.:.|:|.|.|.|:...||.|:|.|:|||.|:||.|.|.|.:.|:
Human  2338 STGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNDNPPLFEQQIYEARISEH 2402

  Fly  2504 LPSGTHVLTPRATDKDEGLNAKLRFNLL--GEHMHRFHIDSETGEISTATTLDREETS-VYHLTL 2565
            .|.|..|...:|.|.|.....||::::|  .:|.| |.|||.|| |.|.:.|.|.... .|.|.|
Human  2403 APHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKH-FVIDSATG-IITLSNLHRHALKPFYSLNL 2465

  Fly  2566 MAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAV 2630
            ...|...    .||..:.::|...|.:.|.|....|.|.:.|.......|...:..|.|.|....
Human  2466 SVSDGVF----RSSTQVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTLVMEVKTTDGDSGIYGH 2526

  Fly  2631 VHYTI---SGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTV 2692
            |.|.|   ..:|:.|  ||.: |.:.|..:|..:|.:  :...::.:.|.|.|.:  .:...:.|
Human  2527 VTYHIVNDFAKDRFY--INER-GQIFTLEKLDRETPA--EKVISVRLMAKDAGGK--VAFCTVNV 2584

  Fly  2693 IL-----RPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGG--IMGD 2750
            ||     ..|: |....|..|    :......|..:.||.|:...:|....|.|||...  .:.:
Human  2585 ILTDDNDNAPQ-FRATKYEVN----IGSSAAKGTSVVKVLASDADEGSNADITYAIEADSESVKE 2644

  Fly  2751 SLRVDPNSGLLSVGQD--GLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQL 2813
            :|.::..||:::..:.  ||:.|   .:..::.|.|..:||..||.|:.:.:.......|...:.
Human  2645 NLEINKLSGVITTKESLIGLENE---FFTFFVRAVDNGSPSKESVVLVYVKILPPEMQLPKFSEP 2706

  Fly  2814 IYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRL------QNDFDGTFEI-TESGEIYTRMRL 2871
            .|...|.|:......|.:::|.     .:|.|:|.|      :::.|.:|.| .:||.:.....|
Human  2707 FYTFTVSEDVPIGTEIDLIRAE-----HSGTVLYSLVKGNTPESNRDESFVIDRQSGRLKLEKSL 2766

  Fly  2872 DREEIGDYAF-VVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRV 2934
            |.|....|.| ::....|....|..:..|.:.:.|.|||.|.| :..:...:.||...||.||::
Human  2767 DHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQI 2831

  Fly  2935 TSSDLDLGANANASYSFSENPG----EKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGAWRA 2995
            .:||.|.|.|....||..::..    |.|.|..::|.||....||.|::|.|.:||||||...:.
Human  2832 RASDADSGTNGQVMYSLDQSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKI 2896

  Fly  2996 ETPIT----ITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQP 3056
            :...|    :|:.|.||:.|.|....|..:..|......::..:..||.|.:..|..::|.:...
Human  2897 QLSSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGG 2961

  Fly  3057 SPM--FSIDPATGE--VFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDA 3117
            .|:  |:::....|  |:.||.:.       |...:.|.||:.|||.   ...|:.:|.:.::||
Human  2962 DPLGQFAVETIQNEWKVYVKKPLD-------REKRDNYLLTITATDG---TFSSKAIVEVKVLDA 3016

  Fly  3118 HNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWIT 3182
            ::|.|..|:..|...:|:|.:.|:.|:::.|.|.......|:.|:|:...... |.:....|.:.
Human  3017 NDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLLGSGAEK-FKLNPDTGELK 3080

  Fly  3183 LVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGST 3247
            ...|:.......|.|:|||||.|  .:..:..:|:.:...|.:.|.||.:.|.:.|.||...|:.
Human  3081 TSTPLDREEQAVYHLLVRATDGG--GRFCQASIVLTLEDVNDNAPEFSADPYAITVFENTEPGTL 3143

  Fly  3248 ILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYH 3312
            :..|.|||.|.|.|..:.||:....:.| ||::|.:|.|.:::.||.:|...|.|::...|.|.
Human  3144 LTRVQATDADAGLNRKILYSLIDSADGQ-FSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGL- 3206

  Fly  3313 PLSSVAMLTIILT--DVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLP 3375
            |....|..|:|::  |:|||||||.::||...:.|:..|||.|.|.:||.:|...||.|.|:.:
Human  3207 PRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSII- 3270

  Fly  3376 SGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFL 3440

Human  3271 ----------------------------------------------------------------- 3270

  Fly  3441 QPVFHFDVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKG-FRIDTNTGLIYVARHLDR 3504
                                                    |.|:.| |.||:.||.:::..:||.
Human  3271 ----------------------------------------SGNEHGKFSIDSKTGAVFIIENLDY 3295

  Fly  3505 ETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVK 3568
            |:.:...|||.|.:.|:  .:.:|.|.|.:::.|.|| .|.|.:..||:.|||.|.:...|.||.
Human  3296 ESSHEYYLTVEATDGGT--PSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVM 3358

  Fly  3569 AIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQTG 3633
            |.|.| ...|:...||||:||...||.||...||:.....||||..|.|.|.:.|.|.|.||:..
Human  3359 ADDAD-GPSNSHIHYSIIDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASDNGSPPRVN 3422

  Fly  3634 SATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKS 3698
            :.||:|::.|||||.|.|:....:..|.||:|.|.|::.|:.:|.|...||.||.:.::.|..:.
Human  3423 TTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGPPFFFTIVTGNDEK 3487

  Fly  3699 WLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQNDNPSTTRSLHIA 3763
            ...|: ..||:.::::..|:........::|.|:|||:..|...:.|.|::::..|.....|.|.
Human  3488 AFEVN-PQGVLLTSSAIKRKEKDHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIF 3551

  Fly  3764 VSLFNGDLPSNVKLADVRPNDIDIVGDYRCRLQKNPAQSQLQLAIPRACDLITTSHT--TPIA-- 3824
            :: .:|:..|...:..:...|.|:.......|.            |:..:|.:.|.|  ..||
Human  3552 IT-SSGEEYSGGVIGKIHATDQDVYDTLTYSLD------------PQMDNLFSVSSTGGKLIAHK 3603

  Fly  3825 --SVFSYTGN----DGKHGDVSSKVSVAFQSFNNETLANSVSIMVRNMTAYHFLANHYRPILEMI 3883
              .:..|..|    |||...|:. ::|..:....|.|.::::|...|:|...|:.:::|.....:
Human  3604 KLDIGQYLLNVSVTDGKFTTVAD-ITVHIRQVTQEMLNHTIAIRFANLTPEEFVGDYWRNFQRAL 3667

  Fly  3884 K-------------SRMSNED----EVILY------------SLLEGGSGNSTNLQLLMAVRL-- 3917
            :             |..|:|.    :|:|:            .||...:.:.|:::.::.||:
Human  3668 RNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDIEEIIGVRILN 3732

  Fly  3918 --------------------------------AKTSYQQPKYLIERLREKRSAFSELLQKE---- 3946
                                            |:.|:..|       |..|:|.  .|.||
Human  3733 VFQKLCAGLDCPWKFCDEKVSVDESVMSTHSTARLSFVTP-------RHHRAAV--CLCKEGRCP 3788

  Fly  3947 -VIVGYE--PCSEPD-------------VCENG--GVC--------------------------- 3966
             |..|.|  ||.|..             ||.:|  |.|
Human  3789 PVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSYVKYRLTENENKLEM 3853

  Fly  3967 SATMRL-------------------LDAH--------------------SFVIQD---------- 3982
            ..||||                   |:.|                    |..:.|
Human  3854 KLTMRLRTYSTHAVVMYARGTDYSILEIHHGRLQYKFDCGSGPGIVSVQSIQVNDGQWHAVALEV 3918

  Fly  3983 -----------------------------------------------SP-----------ALVLS 3989
                                                           ||           ::.|:
Human  3919 NGNYARLVLDQVHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTRHGRSPQVGNGFRGCMDSIYLN 3983

  Fly  3990 G---------------------------------------------PRVVHDYSCQCTSGFSGEQ 4009
            |                                             |.....|.|:|::.:.|..
Human  3984 GQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTH 4048

  Fly  4010 CSRRQDPCLPNPCHSQVQCRRLGSDFQCMCPANRDGKHCEKERSDVCYSKPCRNGGSCQRSPDGS 4074
            |....:||...||.....|......|.|.|.....|:.|  :.|..|..:||:|||:|..|.||:
Human  4049 CEISVNPCSSKPCLYGGTCVVDNGGFVCQCRGLYTGQRC--QLSPYCKDEPCKNGGTCFDSLDGA 4111

  Fly  4075 SYFCLCRPGFRGNQCESVSDSCRPNPCLHGGLCVSLKPGYKCNCTPGRYGRHCERFSYGFQPLSY 4139
              .|.|..||||.:|:|..|.|..||||||.||.:....|.|||:....|||||..:    |..|
Human  4112 --VCQCDSGFRGERCQSDIDECSGNPCLHGALCENTHGSYHCNCSHEYRGRHCEDAA----PNQY 4170

  Fly  4140 MTFP 4143
            ::.|
Human  4171 VSTP 4174

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ft	NP_477497.1	Cadherin_repeat	71..152	CDD:206637
		Cadherin_repeat	163..266	CDD:206637	24/85 (28%)
		Cadherin_repeat	275..378	CDD:206637	28/107 (26%)
		Cadherin_repeat	393..490	CDD:206637	29/103 (28%)
		Cadherin_repeat	498..594	CDD:206637	27/97 (28%)
		Cadherin_repeat	603..704	CDD:206637	34/103 (33%)
		Cadherin_repeat	735..814	CDD:206637	20/85 (24%)
		Cadherin	843..>907	CDD:278457	22/78 (28%)
		Cadherin	950..1026	CDD:278457	21/77 (27%)
		Cadherin_repeat	1053..1149	CDD:206637	32/101 (32%)
		Cadherin_repeat	1157..1274	CDD:206637	26/118 (22%)
		Cadherin_repeat	1282..1380	CDD:206637	30/98 (31%)
		Cadherin_repeat	1390..1485	CDD:206637	26/104 (25%)
		Cadherin_repeat	1497..1597	CDD:206637	31/116 (27%)
		Cadherin_repeat	1621..1699	CDD:206637	17/79 (22%)
		Cadherin_repeat	1720..1818	CDD:206637	34/101 (34%)
		Cadherin_repeat	1827..1918	CDD:206637	26/93 (28%)
		Cadherin_repeat	1926..2023	CDD:206637	33/111 (30%)
		Cadherin_repeat	2031..2162	CDD:206637	42/195 (22%)
		Cadherin_repeat	2172..2274	CDD:206637	30/107 (28%)
		Cadherin_repeat	2282..2380	CDD:206637	35/99 (35%)
		Cadherin_repeat	2388..2487	CDD:206637	36/101 (36%)
		Cadherin_repeat	2495..2592	CDD:206637	32/99 (32%)
		Cadherin_repeat	2600..2694	CDD:206637	22/96 (23%)
		Cadherin_repeat	2710..2806	CDD:206637	22/99 (22%)
		Cadherin_repeat	2814..2909	CDD:206637	24/102 (24%)
		Cadherin_repeat	2917..3009	CDD:206637	34/99 (34%)
		Cadherin	3018..3114	CDD:278457	22/99 (22%)
		Cadherin	3129..3220	CDD:278457	22/90 (24%)
		Cadherin_repeat	3233..3330	CDD:206637	33/98 (34%)
		Cadherin_repeat	3338..3434	CDD:206637	15/95 (16%)
		Cadherin_repeat	3443..3541	CDD:206637	20/98 (20%)
		Cadherin_repeat	3550..3647	CDD:206637	43/96 (45%)
		Cadherin_repeat	3657..3753	CDD:206637	26/95 (27%)
		EGF	4017..4047	CDD:278437	8/29 (28%)
		EGF_CA	4056..4090	CDD:238011	16/33 (48%)
		EGF_CA	4094..4128	CDD:238011	17/33 (52%)
		Laminin_G_1	4156..4306	CDD:278483
		LamG	4428..4543	CDD:238058
FAT1	XP_005262891.1	Cadherin_repeat	38..144	CDD:206637	23/84 (27%)
		Cadherin_repeat	153..252	CDD:206637	27/107 (25%)
		E_set	277..356	CDD:298831	26/79 (33%)
		Cadherin_repeat	371..459	CDD:206637	28/98 (29%)
		Cadherin_repeat	468..565	CDD:206637	34/102 (33%)
		Cadherin_repeat	575..663	CDD:206637	23/111 (21%)
		Cadherin_repeat	724..818	CDD:206637	26/103 (25%)
		Cadherin_repeat	826..923	CDD:206637	28/97 (29%)
		Cadherin_repeat	932..1016	CDD:206637	28/88 (32%)
		Cadherin_repeat	1042..1135	CDD:206637	26/114 (23%)
		Cadherin_repeat	1143..1241	CDD:206637	30/98 (31%)
		Cadherin_repeat	1250..1344	CDD:206637	26/116 (22%)
		Cadherin_repeat	1363..1452	CDD:206637	27/98 (28%)
		Cadherin_repeat	1461..1558	CDD:206637	18/104 (17%)
		Cadherin_repeat	1566..1658	CDD:206637	33/99 (33%)
		Cadherin_repeat	1671..1761	CDD:206637	26/93 (28%)
		Cadherin_repeat	1769..1874	CDD:206637	32/110 (29%)
		Cadherin_repeat	1895..1970	CDD:206637	26/77 (34%)
		Cadherin_repeat	1983..2077	CDD:206637	12/93 (13%)
		Cadherin_repeat	2085..2174	CDD:206637	29/104 (28%)
		Cadherin_repeat	2187..2279	CDD:206637	35/98 (36%)
		Cadherin_repeat	2287..2386	CDD:206637	36/101 (36%)
		Cadherin_repeat	2394..2488	CDD:206637	32/99 (32%)
		Cadherin_repeat	2496..2592	CDD:206637	24/102 (24%)
		Cadherin_repeat	2601..2694	CDD:206637	24/99 (24%)
		Cadherin_repeat	2708..2805	CDD:206637	24/101 (24%)
		Cadherin_repeat	2813..2913	CDD:206637	33/99 (33%)
		Cadherin_repeat	2922..3019	CDD:206637	24/106 (23%)
		Cadherin_repeat	3028..3121	CDD:206637	23/95 (24%)
		Cadherin_repeat	3129..3226	CDD:206637	33/98 (34%)
		Cadherin_repeat	3234..3331	CDD:206637	36/204 (18%)
		Cadherin_repeat	3339..3436	CDD:206637	43/97 (44%)
		Cadherin_repeat	3445..3536	CDD:206637	25/91 (27%)
		Cadherin_repeat	3561..3634	CDD:206637	16/85 (19%)
		LamG	3854..3985	CDD:214598	11/130 (8%)
		EGF_CA	4016..4050	CDD:238011	5/33 (15%)
		EGF_CA	4053..4088	CDD:238011	10/36 (28%)
		EGF	4093..4123	CDD:278437	16/31 (52%)
		EGF_CA	4127..4163	CDD:238011	17/35 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1219
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100175
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.710