Protein Alignment Naprt and NPT1

DIOPT Version :9

• Sequence 1: NP_001097077.1
• Gene: Naprt / 33626
• FlyBaseID: FBgn0031589
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_014852.1
• Gene: NPT1 / 854384
• SGDID: S000005735
• Length: 429
• Species: Saccharomyces cerevisiae
• Alignment Length: 566
• Identity: 105/566 - (18%)
• Similarity: 185/566 - (32%)
• Gaps: 225/566 - (39%)

  Fly    24 VVQPLL-TDLYQITMAYAYWKSDKTDDTAVFDLFFRNNPFHGEFTIFAGLEECLKFLDSFHYSQS 87
            |::.|| ||:|:|||..|.: ::..|.|..:....|::...........|:|...:|.:..:::.
Yeast     5 VIKSLLDTDMYKITMHAAVF-TNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEE 68

  Fly    88 DIEYLKQTLPEGIEHEFFEYLG------------NLTARDVTLYAIDEGTVAFPRVPIIKIEGPL 140
            :||||||.:|. :...:.:|:.            :.|:.::      ||.....::.|: :.|..
Yeast    69 EIEYLKQEIPY-LPSAYIKYISSSNYKLHPEEQISFTSEEI------EGKPTHYKLKIL-VSGSW 125

  Fly   141 IIVQLLETTLLTLV------------NYASLMATNAARYRMVAGKHVKLLEFGLRR---AQGPDG 190
            ....|.|..||:|:            :|.:.:.....:...:....::..|||.||   .:..|.
Yeast   126 KDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRSLKAQDL 190

  Fly   191 GLSASKYSYTGGFD-------GTSNVLAGKLFNIPVKGTHAHAYITSFSSIGELKTRLIKHKQTG 248
            .:.....:..|..|       ||||:|..|.:.:...||.||.::...:||.
Yeast   191 IMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASIS------------- 242

  Fly   249 ILEDLLEHAVRHRALLSHLLDVSTEESSEGELAAMVSYAIAF--PDGFMALVDTYDVKSRETEQA 311
              ||.| ||.::                     ||..:...|  .:..:||.||:..
Yeast   243 --EDYL-HANKN---------------------AMDCWINTFGAKNAGLALTDTFGT-------- 275

  Fly   312 NTEPKHINDIKSENSPPKPKASPSTNGHQNGQGVGHVNGHKTTNGHQNGSAQNNGSRTPKDTDIQ 376
                   :|......||
Yeast   276 -------DDFLKSFRPP------------------------------------------------ 285

  Fly   377 DTSTSTTTTKTTATATGTLKTTTTVSNGTAYLPKYVEKSFRSGLLNFSAVALALNDLGYHALGIR 441
                                          |...||                          |:|
Yeast   286 ------------------------------YSDAYV--------------------------GVR 294

  Fly   442 IDSGDLAYLSCLARETFEKVAERF----KVPWFNKLTIVASNDINEDTILSLN---EQGHKIDCF 499
            .||||..       |..:|::..:    |:|.|:|: |..|:.:|.:..::.:   ::...:..|
Yeast   295 QDSGDPV-------EYTKKISHHYHDVLKLPKFSKI-ICYSDSLNVEKAITYSHAAKENGMLATF 351

  Fly   500 GIGTHLVTCQRQPA--------LGCVYKLVEINGQPRIKLSQDVEK 537
            ||||:.....|:.:        |..|.||:|:||...||:|.::.|
Yeast   352 GIGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGK 397

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naprt	NP_001097077.1	PLN02885	22..667	CDD:178473	105/566 (19%)
		NAPRTase_A	27..521	CDD:238804	96/545 (18%)
NPT1	NP_014852.1	NAPRTase	5..416	CDD:130578	105/566 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344182
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1488
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1808
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		oto99348
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.790