Protein Alignment Naprt and NAPRT1

DIOPT Version :10

• Sequence 1: NP_608818.4
• Gene: Naprt / 33626
• FlyBaseID: FBgn0031589
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_195412.3
• Gene: NAPRT1 / 829848
• AraportID: AT4G36940
• Length: 559
• Species: Arabidopsis thaliana
• Alignment Length: 684
• Identity: 307/684 - (44%)
• Similarity: 411/684 - (60%)
• Gaps: 144/684 - (21%)

  Fly     1 MNDRELGCAGGQFMDRGRM---NQNGVVQPLLTDLYQITMAYAYWKSDKTDDTAVFDLFFRNNPF 62
            |..:|.|..|.|   .||:   ..|.:|.|||.||||.||||||||:.|..:.:||||:||.|||
plant     1 MEKKENGLDGKQ---SGRVINGPTNPMVTPLLNDLYQFTMAYAYWKAGKQSERSVFDLYFRKNPF 62

  Fly    63 HGEFTIFAGLEECLKFLDSFHYSQSDIEYLKQTLPEGIEHEFFEYLGNLTARDVTLYAIDEGTVA 127
            .||:|||||||||:|||.:|:.:..:|::::.:|| |.|..|.:||..|...|:.:|||.||:|.
plant    63 GGEYTIFAGLEECIKFLANFNLTDEEIDFVRDSLP-GCEEAFCDYLRGLDCSDIEVYAISEGSVV 126

  Fly   128 FPRVPIIKIEGPLIIVQLLETTLLTLVNYASLMATNAARYRMVAGKHVKLLEFGLRRAQGPDGGL 192
            ||:||:::||||:.:||||||..|.|:|||||:||||||:|.||||...|||||.||||||||.:
plant   127 FPKVPLLRIEGPVAVVQLLETPFLNLINYASLVATNAARHRFVAGKSKLLLEFGARRAQGPDGAI 191

  Fly   193 SASKYSYTGGFDGTSNVLAGKLFNIPVKGTHAHAYITSFSSIGELKTRLIKHK------------ 245
            |||||.|.||||.||||.|||||.||::|||:||:::||.|:.|:..::::..
plant   192 SASKYCYLGGFDATSNVAAGKLFGIPLRGTHSHAFVSSFMSLDEIVDKVLRSSDGKSTCKDFICL 256

  Fly   246 -QTGILEDLLEHAVRHRALLSHLLDVSTEESSEGELAAMVSYAIAFPDGFMALVDTYDVKSRETE 309
             ||.:.:      :::.:.|..:.    .|:::.||||.:|||:|||:.|:||||||||
plant   257 VQTCLTK------IQNSSSLQGIF----SETNQSELAAFISYALAFPNSFLALVDTYDV------ 305

  Fly   310 QANTEPKHINDIKSENSPPKPKASPSTNGHQNGQGVGHVNGHKTTNGHQNGSAQNNGSRTPKDTD 374
                                                                             
plant   306 ----------------------------------------------------------------- 305

  Fly   375 IQDTSTSTTTTKTTATATGTLKTTTTVSNGTAYLPKYVEKSFRSGLLNFSAVALALNDLGYHALG 439
                                                     .:||:.||.|||||||:|||.|:|
plant   306 -----------------------------------------MKSGIPNFCAVALALNELGYKAVG 329

  Fly   440 IRIDSGDLAYLSCLARETFEKVAERFKVPWFNKLTIVASNDINEDTILSLNEQGHKIDCFGIGTH 504
            ||:|||||||||...|:.|..:....|||.|.|:.:.||||:||:|:.:||:|||::|.|||||:
plant   330 IRLDSGDLAYLSTEVRKFFCAIERDLKVPDFGKMIVTASNDLNEETVDALNKQGHEVDAFGIGTN 394

  Fly   505 LVTCQRQPALGCVYKLVEINGQPRIKLSQDVEKVTMPGNKNAYRLYSADGHALIDLLQKVSEPPP 569
            ||||..|.|||||:||||||.|||||||:||.||::|..|..|||:..:|:.|:|::...:||||
plant   395 LVTCYAQAALGCVFKLVEINNQPRIKLSEDVTKVSIPCKKRTYRLFGKEGYPLVDIMTGENEPPP 459

  Fly   570 AVGQKVLCRHPFQESKRAYVIPSHVESLYKVYWK--SGKICQQLPTLEQVREKVQISLKTLRNDH 632
            .||:::||||||.|||||||:|..||.|.|.||:  :.:..::|..|:::|.:....|:.:|.||
plant   460 KVGERLLCRHPFNESKRAYVVPQRVEELLKCYWRGNADEAREELEPLKELRNRCIKQLENMRPDH 524

  Fly   633 KRTLNPTPYKVAVSDNLYNFIHDLWLQNAPIGEL 666
            .|.||||||||:||..||:|||.|||..||:|||
plant   525 MRRLNPTPYKVSVSAKLYDFIHFLWLNEAPVGEL 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naprt	NP_608818.4	TIM-like beta/alpha barrel domains	22..667	CDD:473867	300/660 (45%)
NAPRT1	NP_195412.3	PLN02885	16..559	CDD:178473	300/666 (45%)