Protein Alignment Naprt and Naprt

DIOPT Version :9

• Sequence 1: NP_001097077.1
• Gene: Naprt / 33626
• FlyBaseID: FBgn0031589
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: NP_766195.2
• Gene: Naprt / 223646
• MGIID: 2442664
• Length: 538
• Species: Mus musculus
• Alignment Length: 645
• Identity: 252/645 - (39%)
• Similarity: 347/645 - (53%)
• Gaps: 126/645 - (19%)

  Fly    17 GRMNQNGVVQPLLTDLYQITMAYAYWKSDKTDDTAVFDLFFRNNPFHGEFTIFAGLEECLKFLDS 81
            |||    ||:||||||||.|||..||::.:..:.|.|:||||:.||.|.|.:.|||::|::||.:
Mouse     9 GRM----VVRPLLTDLYQATMALGYWRAGRACEAAEFELFFRHCPFGGSFALSAGLQDCMRFLRA 69

  Fly    82 FHYSQSDIEYLKQTLPEGIEHEFFEYLGNLTARDVTLYAIDEGTVAFPRVPIIKIEGPLIIVQLL 146
            |....:|:::|...||...:..|||:|..|....||:.|:.||::|||.||::::.|||::||||
Mouse    70 FRLRDADVQFLASVLPPDTDPAFFEHLRALDCSGVTVRALPEGSLAFPGVPLLQVSGPLLLVQLL 134

  Fly   147 ETTLLTLVNYASLMATNAARYRMVAGKHVKLLEFGLRRAQGPDGGLSASKYSYTGGFDGTSNVLA 211
            ||.||.||:||||:||||||.|::||...||||.|||||||||||.:||.|||.||||.:||.||
Mouse   135 ETPLLCLVSYASLVATNAARLRLIAGPDKKLLEMGLRRAQGPDGGFTASIYSYLGGFDSSSNTLA 199

  Fly   212 GKLFNIPVKGTHAHAYITSFSSIGEL--KTRLIKHKQTGILEDLLEHAVRHRALLSHL---LDVS 271
            |:|..:||.||.||:::||||. .|:  ...|......|...||   ..|....|..:   |.:.
Mouse   200 GQLRGVPVAGTLAHSFVTSFSG-SEVPPDPMLAPASSEGPTVDL---PARVNLWLKRVCLYLGLE 260

  Fly   272 TEESSEGELAAMVSYAIAFPDGFMALVDTYDVKSRETEQANTEPKHINDIKSENSPPKPKASPST 336
            .:|...||.||.|:||:|||..|..|:|:|.|:
Mouse   261 EQEPHPGERAAFVAYALAFPRAFQGLLDSYSVR-------------------------------- 293

  Fly   337 NGHQNGQGVGHVNGHKTTNGHQNGSAQNNGSRTPKDTDIQDTSTSTTTTKTTATATGTLKTTTTV 401
                                                                             
Mouse   294 ----------------------------------------------------------------- 293

  Fly   402 SNGTAYLPKYVEKSFRSGLLNFSAVALALNDLGYHALGIRIDSGDLAYLSCLARETFEKVAERFK 466
                           ||||.||.||||||.:|||.|:|:|:|||||...:...|..|.....:|:
Mouse   294 ---------------RSGLPNFLAVALALGELGYRAVGVRLDSGDLLQQAKEIRGIFRTAGAQFQ 343

  Fly   467 VPWFNKLTIVASNDINEDTILSLNEQGHKIDCFGIGTHLVTCQRQPALGCVYKLVEINGQPRIKL 531
            :||...:.|..||:|:|..::.|.::|.:::..||||.:|||.:||::|||||||.:.|||||||
Mouse   344 MPWLESVPIAVSNNIDESELMRLAQKGSEVNVIGIGTSVVTCPKQPSMGCVYKLVSVGGQPRIKL 408

  Fly   532 SQDVEKVTMPGNKNAYRLYSADGHALIDLLQKVSEPPPAVGQKVLCRHPFQESKRAYVIPSHVES 596
            ::|.||.|:||:|.|:|....||..|:||||...||||..||: |...|....:...|.|:.||.
Mouse   409 TEDPEKQTLPGSKAAFRFLGPDGSLLLDLLQLAEEPPPKAGQE-LRVWPRGTQEPCTVKPAQVEP 472

  Fly   597 LYKVYWKSGKICQQLPTLEQVREKVQISLKTLRNDHKRTLNPTPYKVAVSDNLYNFIHDL 656
            |.::|.:.|::|:.||:|::.|...|.||..||..||:..:|..|.||:|:.|...:..|
Mouse   473 LLRLYLQQGQLCEPLPSLDESRRFAQQSLSLLRPAHKQLQSPAVYPVALSEKLRALVDSL 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naprt	NP_001097077.1	PLN02885	22..667	CDD:178473	249/640 (39%)
		NAPRTase_A	27..521	CDD:238804	188/498 (38%)
Naprt	NP_766195.2	PLN02885	13..525	CDD:178473	199/516 (39%)
		NAPRTase_A	15..398	CDD:238804	141/387 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167838347
Domainoid	1	1.000	160	1.000	Domainoid score	I4061
eggNOG	1	0.900	-	-		E1_COG1488
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H82285
Inparanoid	1	1.050	473	1.000	Inparanoid score	I1484
Isobase	1	0.950	-	0	Normalized mean entropy	S4485
OMA	1	1.010	-	-		QHG62487
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005048
OrthoInspector	1	1.000	-	-		oto92902
orthoMCL	1	0.900	-	-		OOG6_102036
Panther	1	1.100	-	-	LDO	PTHR11098
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2731
SonicParanoid	1	1.000	-	-		X3573
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	17	16.740