Protein Alignment Naprt and nampt1

DIOPT Version :9

• Sequence 1: NP_001097077.1
• Gene: Naprt / 33626
• FlyBaseID: FBgn0031589
• Length: 667
• Species: Drosophila melanogaster
• Sequence 2: XP_002661386.1
• Gene: nampt1 / 100330160
• ZFINID: ZDB-GENE-110420-1
• Length: 493
• Species: Danio rerio
• Alignment Length: 666
• Identity: 126/666 - (18%)
• Similarity: 213/666 - (31%)
• Gaps: 266/666 - (39%)

  Fly    28 LLTDLYQIT----------MAYAYW--KSDKTDDTAVFDLFFRNNPFHGEFTIFAGLEECL-KFL 79
            |.||.|::|          ..|:|:  :..|||.|       :......:.|:|.||:..| |:|
Zfish    14 LATDSYKVTHYKQYPPNTSKVYSYFECREKKTDST-------KPRKVKYDKTVFYGLQYILHKYL 71

  Fly    80 DSFHYSQSDIEYLKQTLPEGIEHEFF----------EYLGNLTARDVTLYAIDEGTVAFPRVPII 134
            .....:...|:..|:...|..:.:.|          :|.|:|   .:.:.|:.||:| .||..::
Zfish    72 KGQVITPEKIQEAKEVYREHFQDDVFNEKGWNYILEKYNGHL---PIEIKAVPEGSV-IPRGNVL 132

  Fly   135 -KIEGP----LIIVQLLETTLLTLVNYASLMATNA-------ARYRM-----VAGKHVKLLEFGL 182
             .:|..    ..:...:||.|:. :.|...:|||:       |:|.|     :.|...||.:||.
Zfish   133 FTVENTDPECYWLTNWVETCLVQ-IWYPITVATNSREQKKILAKYLMETSGSLEGLEYKLHDFGY 196

  Fly   183 RRAQGPD-GGLSASKYSYTGGFDGTSNVLAG-----KLFNI--PVKG----THAHAYITSFSSIG 235
            |.....: .|:.||  ::...|.||..| ||     |.:..  ||.|    ...|:.||::....
Zfish   197 RGVSSQETAGIGAS--AHLVNFKGTDTV-AGIGVIKKYYGTKDPVPGFSVPAAEHSTITAWGKDH 258

  Fly   236 ELKTRLIKHKQTGILEDLLEHAVRHRALLSHLLDVSTEESSEGELAAMVSYAIAFPDGFMALV-D 299
            |              :|..||.::.                             ||...:::| |
Zfish   259 E--------------KDAFEHIIKQ-----------------------------FPSVPVSIVSD 280

  Fly   300 TYDVKSRETEQANTEPKHINDIKSENSP--PKPKASPSTNGHQNGQGVGHVNGHKTTNGHQNGSA 362
            :||:.:...:....:.:.:.:::|.::|  .:|
Zfish   281 SYDIYNACEKIWGEDLRSLIEMRSADAPLVVRP-------------------------------- 313

  Fly   363 QNNGSRTPKDTDIQDTSTSTTTTKTTATATGTLKTTTTVSNGTAYLPKYVEKSFRSGLLNFSAVA 427
               .|..|.||                    .||....:  |..:.|:.
Zfish   314 ---DSGNPLDT--------------------VLKVLEIL--GKKFPPEE---------------- 337

  Fly   428 LALNDLGYHALG--IRIDSGDLAYLSCLARETFEKVAERFKVPWFNKLTIVASNDIN--EDTILS 488
               |..||..|.  ||:..||                               ..|||  ::.:..
Zfish   338 ---NSKGYKVLPPYIRVIQGD-------------------------------GVDINTLQEIVEG 368

  Fly   489 LNEQGHKID--CFGIGTHLVTCQRQPALGCVYK--LVEING-------QPRIKLSQDVEKVTMPG 542
            :.|....|:  .||.|..|:....:..|.|.:|  .|..||       .|    ..|..|.:..|
Zfish   369 MKEHRWSIENIAFGSGGALLQKLTRDLLNCSFKCSYVVTNGLGVNVFKDP----VADPNKRSKKG 429

  Fly   543 NKNAYRLYSADGHALIDLLQKVSEPPPAVGQKVLCRHPFQESKRAYVIPSHVESLYKVYWKSGKI 607
            ..:.:|..|.|...|                        :|.|..  :..:.|.|....:::|||
Zfish   430 RLSLHRTPSGDFVTL------------------------EEGKGD--LEEYGEDLLHTVFRNGKI 468

  Fly   608 CQQLPTLEQVREKVQI 623
            .:.. |.::||:..::
Zfish   469 VKTY-TFDEVRDNAKL 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Naprt	NP_001097077.1	PLN02885	22..667	CDD:178473	126/666 (19%)
		NAPRTase_A	27..521	CDD:238804	105/555 (19%)
nampt1	XP_002661386.1	PRK09198	11..481	CDD:236407	126/662 (19%)
		PBEF_like	13..429	CDD:238803	111/583 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900