DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Or24a and GPROR38

DIOPT Version :9

Sequence 1:	NP_523470.3	Gene:	Or24a / 33623	FlyBaseID:	FBgn0026394	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	XP_312288.1	Gene:	GPROR38 / 1273322	VectorBaseID:	AGAP002640	Length:	407	Species:	Anopheles gambiae

Alignment Length:	401	Identity:	88/401 - (21%)
Similarity:	168/401 - (41%)	Gaps:	22/401 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 PMERHYFMVPKFALSLIGFYPEQK--RTVLVKLWSFFNFFILTYGCYAEAYYGIH-YIPINIATA 72
            |.:...|...:..|.:.|.:|..:  |...||:....|...|......|..|.:: |...::...
Mosquito    16 PEDCGMFKFQRKILLIFGCWPPDRLTRRWYVKVLIAVNLITLAICIVGEFRYCLYAYRNGSLIET 80

  Fly    73 LDALCPVASSILSLVKMVAIWWYQDE--LRSLIERVRFLTEQQKSKRKLGYKKRFYTLATQLTFL 135
            ::::||..:....|::|  .|:.::|  ::|.:..|..|.:.: ..|:.||..|.......:|.:
Mosquito    81 IESICPTVARFSGLLRM--CWFLRNEHKIKSALNSVVHLIKNE-HPRETGYTNRITARDQTITKV 142

  Fly   136 LLCCGFCTSTSYSVRHLIDNILRRTHGKDW-------IYETPFKMMFPDLLLRLPLYPITYILVH 193
            |....|.|:..|.:      |.......:|       :...|||::.|.......|:.:|.|.::
Mosquito   143 LFHSSFITAILYGI------IPYFMMAYNWFQGQYPLVKLLPFKVVLPFDSQDPTLFVLTTIFLN 201

  Fly   194 WHGYITVVCFVGADGFFLGFCLYFTVLLLCLQDDVCDLLE-VENIEKSPSEAEEARIVREMEKLV 257
            :....|:......|..|.|.|||.......::.::..|.| |:......|.||..||..|:.::.
Mosquito   202 YASVPTITAMTSTDALFSGVCLYMDGQFQAIRLELEALAETVDKYTLKSSAAETLRINLELRRIN 266

  Fly   258 DRHNEVAELTERLSGVMVEITLAHFVTSSLIIGTSVVDILLFSGLGIIVYVVYTCAVGVEIFLYC 322
            .||..:.::...:........|...:.::.:|....:.:.|..|:..:.|:.||..|.:.:|:|.
Mosquito   267 KRHQTIIDVVSEVRHAFTPTILIVHICAAFMICVISMAMFLAEGINKLTYMPYTFTVLMLLFMYS 331

  Fly   323 LGGSHIMEACSNLARSTFSSHWYGHSVRVQKMTLLMVARAQRVLTIKIPFFSPSLETLTSILRFT 387
            .||:.:.|:...:....:...||......:.:..:|:.||:....:.:|||..|:.|.:.|:|..
Mosquito   332 YGGTVVRESSEAIQTVAYGFPWYQFDRNTRHLVQMMMVRAKYGCNVDVPFFQTSMATFSVIVRSA 396

  Fly   388 GSLIALAKSVI 398
            .|.|.|.||.:
Mosquito   397 MSYITLMKSFL 407

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Or24a	NP_523470.3	7tm_6	68..388	CDD:251636	70/329 (21%)
GPROR38	XP_312288.1	7tm_6	76..397	CDD:251636	70/329 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_2C172
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H119597
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG26277
OrthoDB	1	1.010	-	-		D344326at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9641
Panther	1	1.100	-	-	O	PTHR21137
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	8	7.890