DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CI and mamdc2b

DIOPT Version :9

Sequence 1:	NP_001285599.1	Gene:	Sr-CI / 33621	FlyBaseID:	FBgn0014033	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_017213507.1	Gene:	mamdc2b / 798369	ZFINID:	ZDB-GENE-091117-16	Length:	698	Species:	Danio rerio

Alignment Length:	187	Identity:	53/187 - (28%)
Similarity:	78/187 - (41%)	Gaps:	57/187 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   136 CDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLR-------TGPRHDHTFKNESG-GHYMRMETQ 192
            ||||| ..||:..:        :|....|.:..|       |||..|||    :| ||||.:|..
Zfish   516 CDFES-GLCGFSQD--------KVGDSGDWYLARGPTPTSYTGPGGDHT----TGLGHYMHIEAS 567

  Fly   193 MGAYG-SYHLLSPIYPRSLTL---KTACCFRFHYFMFGAGVDNLVVSVKPVSMPMAT-------- 245
            :...| ...|||.      ||   :...|.:|:|.|:|:|:..|       |:.:.|
Zfish   568 VMLAGHKARLLSS------TLRGTRETQCLQFYYHMYGSGIGQL-------SVYLQTGQENDDRL 619

  Fly   246 MWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDV 302
            :|..          .|:||..||..:::. ...:..|::|.||...|...|||:||:
Zfish   620 LWTS----------HGEQGISWLRASLNY-HYDQQHQIVFEATRGASVRSDIAVDDI 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CI	NP_001285599.1	CCP	22..72	CDD:214478
		CCP	77..125	CDD:214478
		MAM	131..308	CDD:214533	53/187 (28%)
		MAM	136..308	CDD:99706	53/187 (28%)
		Somatomedin_B	335..385	CDD:295334
mamdc2b	XP_017213507.1	MAM	41..175	CDD:279023
		MAM	41..175	CDD:99706
		MAM	178..334	CDD:279023
		MAM	178..334	CDD:99706
		MAM	349..502	CDD:279023
		MAM	349..502	CDD:99706
		MAM	516..674	CDD:279023	53/187 (28%)
		MAM	516..672	CDD:99706	53/187 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	66	1.000	Domainoid score	I9895
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7243
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910