DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CI and mep1a.1

DIOPT Version :9

Sequence 1:	NP_001285599.1	Gene:	Sr-CI / 33621	FlyBaseID:	FBgn0014033	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001025452.1	Gene:	mep1a.1 / 553530	ZFINID:	ZDB-GENE-041001-209	Length:	598	Species:	Danio rerio

Alignment Length:	224	Identity:	52/224 - (23%)
Similarity:	79/224 - (35%)	Gaps:	48/224 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 YVLVGGRTAYCDGERWS----TQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVS 163
            |.::|   .|.|.....    .::.:|..|....| .|.||..:.||....:|....|..:.:
Zfish   228 YKIIG---QYLDFSEMDIVRLNRMYNCSSSLTLLD-QCAFEKINICGMVQSSTDDGDWVHLKS-- 286

  Fly   164 DIHSLRTGPRHDHTFKNESG--GHYMRMETQMGAYGSYHLLSP--IYPRSLTLKTACCFRFHYFM 224
                     ..|||...:..  |:.|..:|..|......|:..  :||:    :...|.:|.|.|
Zfish   287 ---------SEDHTLSGQCRDLGYTMHFDTSSGQAERSALIESRILYPK----RKLQCLQFFYKM 338

  Fly   225 FGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEH----TISIDEMQ--EDFQV 283
            .|:..|.||:            |.|......:.....:..|.|.:.    .|:...||  ..|:.
Zfish   339 TGSAKDRLVI------------WARMDDGTGEVRKLKKLQTIWADEDKTWKIAHVPMQVGAKFRY 391

  Fly   284 IFTAT--DARSQFGDIAIDDVKLMTGSEC 310
            .|.|.  |:.|..|.|.|||:.| |.:.|
Zfish   392 AFQAVKGDSSSSGGGIFIDDISL-TETHC 419

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CI	NP_001285599.1	CCP	22..72	CDD:214478
		CCP	77..125	CDD:214478	4/25 (16%)
		MAM	131..308	CDD:214533	45/188 (24%)
		MAM	136..308	CDD:99706	44/183 (24%)
		Somatomedin_B	335..385	CDD:295334
mep1a.1	NP_001025452.1	ZnMc	26..251	CDD:294052	4/25 (16%)
		Astacin	65..253	CDD:279708	5/27 (19%)
		MAM	261..420	CDD:279023	45/187 (24%)
		MAM	261..419	CDD:99706	44/185 (24%)
		MATH	419..582	CDD:295307	1/1 (100%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5116
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.960