Protein Alignment Sr-CI and Sr-CII

DIOPT Version :9

• Sequence 1: NP_001285599.1
• Gene: Sr-CI / 33621
• FlyBaseID: FBgn0014033
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001188908.1
• Gene: Sr-CII / 44219
• FlyBaseID: FBgn0020377
• Length: 599
• Species: Drosophila melanogaster
• Alignment Length: 639
• Identity: 337/639 - (52%)
• Similarity: 435/639 - (68%)
• Gaps: 50/639 - (7%)

  Fly     1 MEFFWTLAVIVIYCIGHIHGRCERSIDLDNGSINYRQRNVVRFRCNRGYTLQGTVMQTCDRDGRL 65
            |:||..|.:|:.|.:...:|.||.|:||:||....|..|:|.|:||||:.|||..:.||||||||
  Fly     1 MQFFLALTLILAYSLDTANGSCEGSLDLENGRFFTRSNNLVIFQCNRGFVLQGNSIHTCDRDGRL 65

  Fly    66 RGEKPFCASRGCARPEDPENGHVENLSLRADVVCHDGYVLVGGRTAYCDGERWSTQLGSCRRSNH 130
            |.:|||||.:||.:||||.||:|.:..::|::||.||:||.|.|||:||||:||||||:||||||
  Fly    66 REKKPFCARKGCDKPEDPTNGYVLDNPVKAEIVCLDGFVLYGSRTAFCDGEKWSTQLGACRRSNH 130

  Fly   131 TRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESGGHYMRMETQMGA 195
            |.||||||||||||||.||.|...||||:|.|:|.|..|||||:||||.|.|||||||||||:.|
  Fly   131 TMDHSCDFESEDQCGWSAEETIWLPWKRISAVTDFHHPRTGPRYDHTFGNTSGGHYMRMETQIEA 195

  Fly   196 YGSYHLLSPIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEIS 260
            |||||.:||:|||||.|..||||||||||||||||.||:||||.|:.:..|||.||:|.|||||:
  Fly   196 YGSYHFVSPVYPRSLCLNVACCFRFHYFMFGAGVDRLVLSVKPASLQIDDMWNSFRSNSSKFEIT 260

  Fly   261 GQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGTNGFSTTT---EPT 322
            |.|||.|||:||:||:|.|||||:|||||||||||||||||||||||||||.:|:||||   ..:
  Fly   261 GSQGTHWLENTITIDKMHEDFQVVFTATDARSQFGDIAIDDVKLMTGSECGVDGYSTTTTTESAS 325

  Fly   323 APTGSNEQPLVYDMMSCSGRCGTSISASN--ITNNGIVMGCGCNDECLSDETCCLNYLEECTKEL 385
            :...|:|:|||:|||||:.||| |||..:  .::.||||.|||:|.|:.:..||.||.|:|.|||
  Fly   326 SAMSSSEEPLVFDMMSCTFRCG-SISPGSPLFSDEGIVMSCGCDDSCILNNNCCPNYFEKCVKEL 389

  Fly   386 LTTTEDDISSLPPTVTSTSTSTTRKSTTTTTTSTTTTSTTTTKRPTTTTTTTKATTTKRT-TTTK 449
                  ||.| ...:.|.:|:||..|..|||....:.|...::..||..|:|.:||..|| .:||
  Fly   390 ------DIGS-NVFLNSANTTTTSISRNTTTEKVFSISLEASRSFTTPRTSTNSTTFPRTQISTK 447

  Fly   450 KPTTTSTTPKPTTTTSTTPKSTTSTTSTTSTTPTTTTTINVFTTKKTTIMIPTSSTEKTTGINTT 514
            |...|..|   .|.|||.|     |.:...:.|      ::|:::..|:              ||
  Fly   448 KLLNTHET---LTETSTIP-----TRNKKLSQP------SIFSSQHITV--------------TT 484

  Fly   515 MKTRKRITWNVDPQDIEGHMDTSGSTPNPALVVLYLLLAIVLVVVLANVVNRWIIPITGSKTSSE 579
            ...|.|..::   :||.|.:|.:.:.|:|||:|:|||:.::||:|:||:.....|....|...:|
  Fly   485 TTDRSRKDYH---EDIAGQLDMNTNIPHPALIVMYLLIGVILVIVVANLKQLCKILSKNSSRDNE 546

  Fly   580 KAVRFKKAFDSLKKQRKR----NSMDDQPLCDSDNDDVEYFEEMGVDIRHRTDL 629
            |.|.|||||:.|:|.|:.    |.| ||.||.:.::|::|||:|.::||..|||
  Fly   547 KVVSFKKAFEGLRKPRRLSQNCNGM-DQHLCSAFDEDLDYFEDMDMNIRMVTDL 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CI	NP_001285599.1	CCP	22..72	CDD:214478	29/49 (59%)
		CCP	77..125	CDD:214478	29/47 (62%)
		MAM	131..308	CDD:214533	134/176 (76%)
		MAM	136..308	CDD:99706	130/171 (76%)
		Somatomedin_B	335..385	CDD:295334	27/51 (53%)
Sr-CII	NP_001188908.1	CCP	22..72	CDD:153056	29/49 (59%)
		CCP	77..125	CDD:214478	29/47 (62%)
		MAM	136..312	CDD:279023	134/175 (77%)
		MAM	136..308	CDD:99706	130/171 (76%)
		Somatomedin_B	341..387	CDD:279385	23/46 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45470078
Domainoid	1	1.000	66	1.000	Domainoid score	I9895
eggNOG	1	0.900	-	-		E1_2CMY0
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5116
Isobase	1	0.950	-	0	Normalized mean entropy	S8224
OMA	1	1.010	-	-		QHG26955
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006092
OrthoInspector	1	1.000	-	-		mtm9576
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23282
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7243
	11	10.850