DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sr-CI and Mamdc4

DIOPT Version :9

Sequence 1:NP_001285599.1 Gene:Sr-CI / 33621 FlyBaseID:FBgn0014033 Length:629 Species:Drosophila melanogaster
Sequence 2:NP_001074668.2 Gene:Mamdc4 / 381352 MGIID:2685841 Length:1232 Species:Mus musculus


Alignment Length:291 Identity:74/291 - (25%)
Similarity:107/291 - (36%) Gaps:79/291 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 VLVGGRTAYCDGERWSTQLGSCRRSNHTRDHSCDFESEDQCGWEAETTFRRPWKRVSTVS-DIHS 167
            |..|...:|...:..|.|.|.|.:..     |||||: ..|||.     ..||..:...| |..|
Mouse   956 VAAGVEYSYMALDDISLQDGPCPQ
PG-----SCDFET-GLCGWS-----HLPWPSLGGYSWDWSS 1009

  Fly   168 LRTGPRH-----DHTFKNESGGHYMRMETQM---GAYGSYHLLSPIYPRSLTLKTACCFRFHYFM 224
            ..|..|:     |||...|: ||:...||.:   |...::....|     |...|..|.||.|:|
Mouse  1010 GATPSRYPQPSVDHTLGTEA-GHFAFFETSVLGPGGQAAWLRSEP-----LPATTVSCLRFWYYM 1068

  Fly   225 -----FGAGVDNLVVSVKPVSMPMATMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVI 284
                 |..|...:::|   .:.....:|.:          .|....|||:..|.:.. .|:||::
Mouse  1069 GFPEHFYKGELRVLLS---SARGQLAVWYQ----------GGHLRDQWLQVQIELSN-SEEFQIV 1119

  Fly   285 FTAT-DARSQFGDIAIDDVKLMTGSECGTNGFSTTTEPTAPTGSNEQP----------LVYDM-- 336
            |.|| ..:...|.||||||:.:.|.:|        .:|:...|....|          |::.|  
Mouse  1120 FEATLGGQPALGPIAIDDVQYLAGQQC--------KQ
PSPSQGEVAAPVSVPVAVGGALLFFMFL 1176

  Fly   337 -------------MSCSGRCGTSISASNITN 354
                         ..|.|:..|..:||...|
Mouse  1177 VLMGLGGWHWLQKQHCPGQRSTDAAASGFAN 1207

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sr-CINP_001285599.1 CCP 22..72 CDD:214478
CCP 77..125 CDD:214478 6/20 (30%)
MAM 131..308 CDD:214533 54/191 (28%)
MAM 136..308 CDD:99706 53/186 (28%)
Somatomedin_B 335..385 CDD:295334 7/35 (20%)
Mamdc4NP_001074668.2 MAM 71..227 CDD:279023
MAM 71..224 CDD:99706
LDLa 234..266 CDD:238060
MAM 254..427 CDD:214533
MAM 277..427 CDD:99706
LDLa 462..495 CDD:238060
MAM 498..653 CDD:279023
MAM 499..650 CDD:99706
MAM 660..817 CDD:214533
MAM 665..817 CDD:99706
MAM 823..979 CDD:279023 7/22 (32%)
MAM 823..977 CDD:99706 6/20 (30%)
MAM 983..1148 CDD:279023 55/198 (28%)
MAM 983..1144 CDD:99706 53/186 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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