DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CI and Mdga2

DIOPT Version :9

Sequence 1:	NP_001285599.1	Gene:	Sr-CI / 33621	FlyBaseID:	FBgn0014033	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	NP_001180195.2	Gene:	Mdga2 / 320772	MGIID:	2444706	Length:	956	Species:	Mus musculus

Alignment Length:	209	Identity:	61/209 - (29%)
Similarity:	88/209 - (42%)	Gaps:	27/209 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 HTRDHSCDFESEDQCGWEAETTFRRPWKRVSTV--SDIHSLRTGPRHDHTFKNESGGHYMRMETQ 192
            |.|:..|.||..:.|.:..:.|....|.:.||.  :..::..|||..|.:...|  |.||.:||.
Mouse   742 HLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPSADRSGSKE--GFYMYIETS 804

  Fly   193 MGAY--GSYHLLSPIY------PRSLTLKTACCFRFHYFMFG--AGVDNLVVSVKPVSMPMATMW 247
            ....  ....||||::      |...| .:|.||.|.|.|:|  .||.|:.:.:|..:.....:|
Mouse   805 RPRLEGEKARLLSPVFSIAPKNPYGPT-NSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLW 868

  Fly   248 NRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGT 312
            :.          ||.:|.:|.|..::|..: ..||:||.........||||||||.:..| ||..
Mouse   869 SS----------SGNKGQRWNEAHVNIYPI-TSFQLIFEGIRGPGIEGDIAIDDVSIAEG-ECAK 921

  Fly   313 NGFSTTTEPTAPTG 326
            ....|........|
Mouse   922 QDLPTKNSVDGAVG 935

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CI	NP_001285599.1	CCP	22..72	CDD:214478
		CCP	77..125	CDD:214478
		MAM	131..308	CDD:214533	55/188 (29%)
		MAM	136..308	CDD:99706	54/183 (30%)
		Somatomedin_B	335..385	CDD:295334
Mdga2	NP_001180195.2	IG_like	48..128	CDD:214653
		IGc2	54..117	CDD:197706
		IG_like	154..219	CDD:214653
		Ig	155..219	CDD:143165
		IG_like	251..328	CDD:214653
		IGc2	256..317	CDD:197706
		Ig	355..427	CDD:143165
		IG_like	451..536	CDD:214653
		IGc2	457..522	CDD:197706
		Ig_2	543..618	CDD:290606
		MAM	748..921	CDD:279023	57/187 (30%)
		MAM	748..919	CDD:99706	55/185 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I9081
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910