DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Sr-CI and Mdga2

DIOPT Version :9

Sequence 1:	NP_001285599.1	Gene:	Sr-CI / 33621	FlyBaseID:	FBgn0014033	Length:	629	Species:	Drosophila melanogaster
Sequence 2:	XP_008762910.2	Gene:	Mdga2 / 314180	RGDID:	735131	Length:	956	Species:	Rattus norvegicus

Alignment Length:	209	Identity:	61/209 - (29%)
Similarity:	88/209 - (42%)	Gaps:	27/209 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   130 HTRDHSCDFESEDQCGWEAETTFRRPWKRVSTV--SDIHSLRTGPRHDHTFKNESGGHYMRMETQ 192
            |.|:..|.||..:.|.:..:.|....|.:.||.  :..::..|||..|.:...|  |.||.:||.
  Rat   742 HLREFHCGFEDGNICLFTQDDTDNFDWTKQSTATRNTKYTPNTGPNADRSGSKE--GFYMYIETS 804

  Fly   193 MGAY--GSYHLLSPIY------PRSLTLKTACCFRFHYFMFG--AGVDNLVVSVKPVSMPMATMW 247
            ....  ....||||::      |...| .:|.||.|.|.|:|  .||.|:.:.:|..:.....:|
  Rat   805 RPRLEGEKARLLSPVFSIAPKNPYGPT-NSAYCFSFFYHMYGQHIGVLNVYLRLKGQTTIENPLW 868

  Fly   248 NRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSECGT 312
            :.          ||.:|.:|.|..::|..: ..||:||.........||||||||.:..| ||..
  Rat   869 SS----------SGNKGQRWNEAHVNIYPI-TSFQLIFEGIRGPGIEGDIAIDDVSIAEG-ECAK 921

  Fly   313 NGFSTTTEPTAPTG 326
            ....|........|
  Rat   922 QDLPTKNSVDGAVG 935

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sr-CI	NP_001285599.1	CCP	22..72	CDD:214478
		CCP	77..125	CDD:214478
		MAM	131..308	CDD:214533	55/188 (29%)
		MAM	136..308	CDD:99706	54/183 (30%)
		Somatomedin_B	335..385	CDD:295334
Mdga2	XP_008762910.2	IG	48..128	CDD:214652
		Ig_3	134..219	CDD:404760
		Ig strand B	155..159	CDD:409353
		Ig strand C	168..172	CDD:409353
		Ig strand E	199..203	CDD:409353
		Ig strand F	213..218	CDD:409353
		Ig strand A	244..248	CDD:409353
		IGc2	256..317	CDD:197706
		Ig strand B	258..268	CDD:409353
		Ig strand C	274..278	CDD:409353
		Ig strand C'	280..282	CDD:409353
		Ig strand D	287..292	CDD:409353
		Ig strand E	293..299	CDD:409353
		Ig strand F	306..314	CDD:409353
		Ig	349..424	CDD:416386
		Ig strand B	355..359	CDD:409353
		Ig strand C	370..374	CDD:409353
		Ig strand E	400..404	CDD:409353
		Ig strand F	414..419	CDD:409353
		Ig strand G	428..431	CDD:409353
		Ig_3	441..518	CDD:404760
		Ig strand B	461..468	CDD:409353
		Ig strand C	474..479	CDD:409353
		Ig strand C'	482..484	CDD:409353
		Ig strand D	490..494	CDD:409353
		Ig strand E	498..502	CDD:409353
		Ig strand F	511..519	CDD:409353
		MAM	748..920	CDD:395504	56/186 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	77	1.000	Domainoid score	I8632
eggNOG	1	0.900	-	-		E1_2CMY0
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810