DRSC/TRiP Functional Genomics Resources

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Protein Alignment Sr-CI and MAMDC2

DIOPT Version :9

Sequence 1:NP_001285599.1 Gene:Sr-CI / 33621 FlyBaseID:FBgn0014033 Length:629 Species:Drosophila melanogaster
Sequence 2:NP_694999.3 Gene:MAMDC2 / 256691 HGNCID:23673 Length:686 Species:Homo sapiens


Alignment Length:210 Identity:68/210 - (32%)
Similarity:90/210 - (42%) Gaps:37/210 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   121 QLGSCRRSNH--TRDHSCDFESEDQCGWEAETTFRRPWKRVSTVSDIHSLRTGPRHDHTFKNESG 183
            |||||..|..  .....|.|| :|:|.:..|...|..|.|  ...:..:..|||:.|||    :|
Human   492 QLGSCS
SSEKLPPPPGECTFE-QDECTFTQEKRNRSSWHR--RRGETPTSYTGPKGDHT----TG 549

  Fly   184 -GHYMRMETQMGAYG-SYHLLS-PIYPRSLTLKTACCFRFHYFMFGAGVDNLVVSV-KPVSMPMA 244
             |:||.:|.....|| ...||| |:  |.::.|.  |..|.|.|:|.|...|.|.: |......:
Human   550 VGYYMYIEASHMVYGQKARLLSRPL--RGVSGKH--CLTFFYHMYGGGTGLLSVYLKKEEDSEES 610

  Fly   245 TMWNRFRANCSKFEISGQQGTQWLEHTISIDEMQEDFQVIFTATDARSQFGDIAIDDVKLMTGSE 309
            .:|.|          .|:|...||...|.. ..:...|:||.|....|...||||||||...| .
Human   611 LLWRR----------RGEQSISWLRALIEY-SCERQHQIIFEAIRGVSIRSDIAIDDVKFQAG-P 663

  Fly   310 CG--------TNGFS 316
            ||        ::|:|
Human   664 CGEMEDTTQQSSGYS 678

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Sr-CINP_001285599.1 CCP 22..72 CDD:214478
CCP 77..125 CDD:214478 3/3 (100%)
MAM 131..308 CDD:214533 57/180 (32%)
MAM 136..308 CDD:99706 57/175 (33%)
Somatomedin_B 335..385 CDD:295334
MAMDC2NP_694999.3 MAM 26..167 CDD:279023
MAM 26..167 CDD:99706
MAM 170..327 CDD:279023
MAM 170..327 CDD:99706
MAM 342..497 CDD:279023 4/4 (100%)
MAM 342..496 CDD:99706 3/3 (100%)
MAM 509..666 CDD:279023 59/179 (33%)
MAM 509..664 CDD:99706 58/177 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 521..543 6/23 (26%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 665..686 3/14 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S8224
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.860

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