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Protein Alignment ed and kirrel1a

DIOPT Version :10

Sequence 1:	NP_523469.2	Gene:	ed / 33619	FlyBaseID:	FBgn0000547	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	NP_001349348.1	Gene:	kirrel1a / 405804	ZFINID:	ZDB-GENE-040426-2126	Length:	819	Species:	Danio rerio

Alignment Length:	676	Identity:	159/676 - (23%)
Similarity:	244/676 - (36%)	Gaps:	176/676 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 WTRWTANPAQFDNVAIG---EVQLSSGYRLDFQPERGIYDLQIKNVSYNRDNGRFECRIKAKGTG 134
            ||:        |.:|:|   :::....||:....:.|.|:|:|.....: |:..:||    :.|.
Zfish    52 WTK--------DGLALGIGEDLRAWPRYRVLRLVDVGQYNLEISAAELS-DDSLYEC----QATE 103

  Fly   135 ADVHQEFHNLTVLTPPHPPVISPGNIAVATEDKPMELTCSSIGGSPDPTITWYREGSNTPLP--- 196
            |.:......||||.||..|||......:.|...|..::|.|.|..|...|.|.::|    ||
Zfish   104 AALRSRRAKLTVLIPPDEPVIEGSPEILLTAGVPYNMSCVSRGAKPASVIEWQKDG----LPIEG 164

  Fly   197 ---ATVLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEATATLNVNYYPRV--E 256
               .|.:....|...|.:.|.|.|...|.|..:.||..|.|:..|||  ||.||||::.|.|  .
Zfish   165 AVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKR--ATITLNVHHPPVVTLS 227

  Fly   257 VGPENPLRVERDRTAKLECNVDAKPKVPNVRWNRNGRFISSSLVHTIHRVSVQDAGKYT----CI 317
            :.|.:.|..||   ....|...|.|.:...:|.:.|..|..:.....  |:..|...:|    |.
Zfish   228 IEPRSVLEGER---VTFTCQATANPPIMGYKWAKGGVVIQGARESVF--VTKADHSFFTEPVSCQ 287

  Fly   318 ADNGLGKTGEQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLKENSPDFRY 382
            ..|.:|.| ...:::|:.:.|::|:|.|....:....||:.|....|| |:|:.|.|:.|.....
Zfish   288 VFNAVGST-NVSILVDVHFGPILVVEPKPVTVDVDSDVTLNCKWAGNP-PLTLTWTKKGSSMVLS 350

  Fly   383 NGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPVVHVG 447
            |.:.|.|.||....||.|:|:|  |:...|      ||.:.|.|.|...|    |..::|..:..
Zfish   351 NNNQLYLKSVSQADAGQYVCKA--IVPRIG------VGETEVTLTVNGPP----IISSEPFQYAV 403

  Fly   448 NG----VTLTCSANPPG----WPVPQYRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGN------ 498
            .|    |....::.||.    |...:..|.:: .|..|....:     :.|.|.|..|.
Zfish   404 RGERGEVKCYIASTPPPDKIVWAWKENVWEKE-KGTLSERYTV-----EQSKPSAQGGAVLSTLT 462

  Fly   499 ---------EGKYHCHAVNELGIGMMATIVLEIHQPP-----------------------QFLAK 531
                     :..|:|.|.|..|.|.|...:.|:...|                       .||.:
Zfish   463 INNIMESDFQSTYNCTAWNSFGSGTMIISLEEMEIVPVGIIAGGTVGCSILLLLCLLALVLFLYR 527

  Fly   532 LQQHMTRRVA--------------------DTDYTVTCSAKGKP----------APSVKWLKDAV 566
            .::...|.|.                    |:....|.:...|.          :||.:..||.:
Zfish   528 QRKGSRRGVTLGKPDIKVETINKESHSLEEDSGSVSTATRMVKAMYSFLPSVTLSPSSQPFKDDI 592

  Fly   567 EILPEENLYEVQTNPDQGL----NGMVTVQSQL--------------KFRGKARPNG-------- 605
            ::..|.....:.|..|..|    ||...|::..              .:|..::|.|
Zfish   593 DLKQELRSDTLDTRQDYELKDPTNGYYNVRASTHDEGRPASRSMHYSDYRTSSQPGGAAAVVSSS 657

  Fly   606 --------------NALVPGDR-GLY 616
                          ::|.||.| |.|
Zfish   658 SGPPPGATAGPGTPSSLAPGSRAGCY 683

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.