DRSC/TRiP Functional Genomics Resources

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Protein Alignment ed and CG17716

DIOPT Version :9

Sequence 1:NP_001260013.1 Gene:ed / 33619 FlyBaseID:FBgn0000547 Length:1332 Species:Drosophila melanogaster
Sequence 2:NP_001286391.1 Gene:CG17716 / 36521 FlyBaseID:FBgn0000633 Length:822 Species:Drosophila melanogaster


Alignment Length:524 Identity:119/524 - (22%)
Similarity:177/524 - (33%) Gaps:182/524 - (34%)


- Green bases have known domain annotations that are detailed below.


  Fly   110 LQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHN-----LTVLTPPHPPV-------ISPGNIAV 162
            |.|.||.. .|:|:::|  :|:.|    .:...|     |.||..|.||.       :...|:.|
  Fly   298 LTITNVML-EDDGKWQC--EAENT----RRYTENARPVKLVVLDRPKPPYLLIDSRRLDASNLFV 355

  Fly   163 -ATEDKPMELTCSSIGGSPDPTITWYREGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAK- 225
             ..|:..:.|.|.|.||:|.||:||          ..:|..|........:..::...|..|.| 
  Fly   356 PVKENSELNLACVSEGGNPRPTLTW----------EVLLSPGVDRHAQKVSAEVLELEEIKGEKL 410

  Fly   226 ----YKCVVRNRAMNEGKRLEATATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNV 286
                ||       :|.|.:.||                                      ::|.|
  Fly   411 DKDGYK-------INSGAKSEA--------------------------------------RLPAV 430

  Fly   287 -RWNRNGRFISSSLVHTIHRVSVQDAGKYTCIADNGLGKTGEQ-ELILDILYPPMVVIESKT--- 346
             |.:.|.|.:                    |:.::...|..:. .|:||:.|.|...| |:|   
  Fly   431 YRAHHNARIL--------------------CVMEHPTLKIRQNASLLLDVQYTPSFAI-SRTPGF 474

  Fly   347 -REAEEGDTVTIRCNVTANPAPVTIEWLKE--NSPDFRYNGDVLTLTSVRADHAGNYIC--RAVN 406
             ....||..|:::|:|.:|| |.|..|.|:  ::|..:.....|..||:|.:|:|.|.|  |.:|
  Fly   475 GYPLREGIEVSLKCDVDSNP-PSTPRWQKDDGDTPVPQTGDGFLNFTSIRREHSGWYKCTSRHLN 538

  Fly   407 IMQSQ-GMERSERVGNSTV----------ALLVRHRPGQAYITPNKPVVHVGNGVTLTCSANPPG 460
            ...|. |...|.|..:..|          .....|.|.:..:.     |.:|..|||.|.....|
  Fly   539 FQYSSIGYYLSVRFDSVDVTSEPDDQDVSVAAASHNPNKGQLE-----VQLGGAVTLQCPQGSLG 598

  Fly   461 -W----PVPQYRWFRDMDGEFSSTQKILAQGP-----QYSIPKAHLGNEGKYHCHAVNELGIGMM 515
             |    |:             |:..:.|..|.     |:|:......:.|.|.|           
  Fly   599 CWSHLDPI-------------SARLRGLGYGSSQPTGQFSLKDVMYQDAGMYKC----------- 639

  Fly   516 ATIVLEIHQPPQFLAKLQQHMTRRVADTDYTVTCSAKGKPAPSVKWLKDAVEILPEENLY---EV 577
                  :.|.|....||         :...:||.|.||  ||:|..|.......|...|:   |.
  Fly   640 ------VGQSPTNKKKL---------EVLQSVTVSVKG--APTVMALNATPVAYPGSPLHLNVEF 687

  Fly   578 QTNP 581
            ..||
  Fly   688 CANP 691

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
edNP_001260013.1 Ig 50..147 CDD:299845 11/41 (27%)
I-set 146..249 CDD:254352 29/115 (25%)
Ig 168..249 CDD:299845 21/85 (25%)
IGc2 268..323 CDD:197706 6/55 (11%)
Ig_3 341..406 CDD:290638 24/72 (33%)
Ig_2 437..514 CDD:290606 17/86 (20%)
I-set 526..633 CDD:254352 17/59 (29%)
Ig 546..632 CDD:143165 14/39 (36%)
IG_like 654..736 CDD:214653
Ig 656..734 CDD:143165
FN3 741..848 CDD:238020
CG17716NP_001286391.1 IG_like 244..332 CDD:214653 11/40 (28%)
Ig 254..323 CDD:143165 9/31 (29%)
Ig 359..452 CDD:299845 29/167 (17%)
Ig_3 477..536 CDD:290638 20/59 (34%)
IG_like 479..550 CDD:214653 24/71 (34%)
IG_like 578..660 CDD:214653 23/125 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR11640
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
22.010

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