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Protein Alignment ed and Kirrel1

DIOPT Version :10

Sequence 1:	NP_523469.2	Gene:	ed / 33619	FlyBaseID:	FBgn0000547	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_011238330.1	Gene:	Kirrel1 / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus

Alignment Length:	814	Identity:	178/814 - (21%)
Similarity:	289/814 - (35%)	Gaps:	226/814 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    73 WTRWTANPAQFDNVAIGEVQLSSG------YRLDFQPERGIYDLQIKNVSYNRDNGRFECRIKAK 131
            ||:        |.:|:|   :..|      ||:....:.|.|:|:|.:...: |:..:||    :
Mouse    85 WTK--------DGLALG---MGQGLKAWPRYRVVGSADAGQYNLEITDAELS-DDASYEC----Q 133

  Fly   132 GTGADVHQEFHNLTVLTPPHPPVISPGNIAVATEDKPMELTCSSIGGSPDPTITWYREGSNTPLP 196
            .|.|.:......||||.||....|..|.:.:.....|..|||.:....|..||.|:|:|:.....
Mouse   134 ATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGA 198

  Fly   197 AT---VLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEATATLNVNYYPRVEVG 258
            .|   :||.| |.:.|.:.|.|.|...|.|..:.|...|.|:..||  |.:..|:|::.|.|.:.
Mouse   199 VTSTELLKDG-KRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGK--ETSIELDVHHPPTVTLS 260

  Fly   259 PENPLRVERDRTAKLECNVDAKPKVPNVRWNRNGRFISSSLVHTIHRVSVQDAGKYT----CIAD 319
            .|....:|.:|.. ..|...|.|::...||.:.|..|..:  |.....:..|...:|    |...
Mouse   261 IEPQTVLEGERVI-FTCQATANPEILGYRWAKGGFLIEDA--HESRYETNVDYSFFTEPVSCEVY 322

  Fly   320 NGLGKTGEQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLKENS------- 377
            |.:|.|....|: ::.:.|.:|:..|....:.|..||:.|....|| |:|:.|.|::|
Mouse   323 NKVGSTNVSTLV-NVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNP-PLTLTWTKKDSNMGPRLP 385

  Fly   378 ---PDFRYNGDVLT------LTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRPG 433
               |:...:..||:      |.||....||.|.|||:          ..|:|       |..|..
Mouse   386 GSPPEANLSAQVLSNSNQLLLKSVTQADAGTYTCRAI----------VPRIG-------VAEREV 433

  Fly   434 QAYITPNKPVVHV--------GNGVTLTC---SANPP---GWPVPQYRWFRDMDGEFSSTQKILA 484
            ..|:. ..|::..        |:|..:.|   |..||   .|     .|          .:..|.
Mouse   434 PLYVN-GPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAW-----AW----------KENFLE 482

  Fly   485 QG--PQYSIPKAHLGN----------------EGKYHCHAVNELGIGMMATIVLEIHQ----PPQ 527
            .|  .:|::.:.:.|:                :..|:|.|.|..|.|   |.::::.:    |..
Mouse   483 VGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPG---TAIIQLEEREVLPVG 544

  Fly   528 FLA-----------------------------------KL--------QQHMTRRVADTDYTVTC 549
            .:|                                   ||        ::.:|......|.|.:.
Mouse   545 IIAGATIGAGILVVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASI 609

  Fly   550 SAKGKPAPSV-KWLKDAVEILPEENLYEVQTNPDQGL----NGMVTVQSQLKFRGKARPNGNALV 609
            |...:...:: ...||.|::..:.....:.|..:..:    ||...|::.     :.||:..|::
Mouse   610 STATRVMKAIYSSFKDDVDLKQDLRCDTIDTREEYEMKDPTNGYYNVRAH-----EDRPSSRAVL 669

  Fly   610 PGDRGLYTCLYQNEVNSANSSMQLRIEHEP--IVLHQYNKVAFDIRETAEVVCKVQAYPKPEFQW 672
            ..|   |........:...||   |:.|..  ..|:.|::.                 |..:
Mouse   670 YAD---YRAPGPTRFDGRPSS---RLSHSSGYAQLNTYSRA-----------------PASD--- 708

  Fly   673 QFGNNPSPLTMSSDGHYEISTTTDNNDIYTSVLKINSLTH-----SDYGEYTCRVANTLDTIRAP 732
             :|..|:|...|:.|    .|.|.:...|.:..|.||  |     :.|..|      .|...:||
Mouse   709 -YGTEPTPSGPSAPG----GTDTTSQLSYENYEKFNS--HPFPGAAGYPTY------RLGYPQAP 760

  Fly   733 IRLQQKGPPE--KPTNLRATEVGHNYVSLSWDPG 764
            ....::.|.|  .|....||....:|.|...|.|
Mouse   761 PSGLERTPYEAYDPIGKYATATRFSYTSQHSDYG 794

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.