Protein Alignment ed and LOC108648322

DIOPT Version :10

• Sequence 1: NP_523469.2
• Gene: ed / 33619
• FlyBaseID: FBgn0000547
• Length: 1332
• Species: Drosophila melanogaster
• Sequence 2: XP_017952078.1
• Gene: LOC108648322 / 108648322
• XenbaseID: XB-GENE-29091151
• Length: 623
• Species: Xenopus tropicalis
• Alignment Length: 554
• Identity: 117/554 - (21%)
• Similarity: 180/554 - (32%)
• Gaps: 156/554 - (28%)

  Fly   234 AMNEGKRLEATATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPK-VPNVRWNRNG-RFIS 296
            |.|.|....||.:.:.|:           .......:..|.|||.:..: .|...|.::| |..:
 Frog    14 AENAGAAGRATVSFSPNW-----------ASAFTSESVTLTCNVSSSAQGEPPYFWYKDGVRMET 67

  Fly   297 SSLVHTIHRVSVQDAGKYTC--------------IADNGLGKTGEQELILDILYPPMVVIESKTR 347
            ....:||......|:|.|.|              |:|:          .|.:..||.|.
 Frog    68 KQQKYTIFNAKKSDSGVYQCKSHSSDRSDSVTLTISDD----------YLSLKVPPFVF------ 116

  Fly   348 EAEEGDTVTIRCNVTANPAPVTIEWLKEN-----SPDFRYN-GDVLTLTSVRADHAGNYIC-RAV 405
               |||.:.:.|.........|.:..|.|     ||...:| |.|...||      |:||| |||
 Frog   117 ---EGDNLQVSCAGYPGYKADTAKLNKGNQLIGSSPSGNFNFGRVTMATS------GSYICYRAV 172

  Fly   406 N---IMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPVVHVGNGVTLTCSAN-PPGWPVPQ- 465
            .   |..:|         .|:|.:.|:.......|..:...|..|:.:|:||... .|.....:
 Frog   173 KHHLIYYNQ---------KSSVYISVKELFSSPQIKVSTDQVTEGDRMTITCDTELSPHRETTEL 228

  Fly   466 ----YRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGNEGKYHCHAVNELGI----GMMATIVLEI 522
                ||...::.| ||.:.       ||.:..|.|.:.|.|.|....:.||    ....:|.:..
 Frog   229 QFAFYRNGHNVQG-FSLSN-------QYGVSSAQLEDSGYYTCEIRAQSGIVNKKSDRKSIQIRT 285

  Fly   523 HQPPQFLAKLQQHMTRRVADTDYTVTCSA-KGKPAPSVKWLKDAVEI-------LPEENLYEVQT 579
            .:......:|:....:.:|.....:.||. ||.......|.|....|       .||:.......
 Frog   286 KKLAGVRVRLEPAGGQVIAGEKLEILCSVEKGMGLLRYSWCKQPTLICNTKEAAAPEQRFVAESV 350

  Fly   580 NPDQGLNGMVTVQSQLKFRGKARPNGNALVPGDRGLYTCLYQ-----NEVNSANSSMQLRIEHEP 639
            :.|.|                             |.|.|:..     ..:.|||.|:.::   ||
 Frog   351 SEDYG-----------------------------GEYQCIITRTATGESIRSANISISVQ---EP 383

  Fly   640 I----VLHQYNKVAFDIRETAEVVCKVQAYPKPEFQWQFGNNPSPLTMSSDGH----YEISTTTD 696
            :    :..:.:::|..:.:...:.|.|.....|.|.|...|       .:.||    |::..:
 Frog   384 VADARITPEEDELAVKVEDNLCLTCSVAKGTNPLFLWIHNN-------KTIGHESVLYQVRES-- 439

  Fly   697 NNDIYTSVLKINSLTHSDYGEYTCRVANTLDTIR 730
                 ..||.|.|......|.|.|.|.|.|.:.|
 Frog   440 -----GKVLCIESAQLQHAGTYWCEVRNQLSSNR 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_523469.2	V-set	50..147	CDD:462230
		Ig	153..249	CDD:472250	5/14 (36%)
		Ig strand B	169..173	CDD:409353
		Ig strand C	183..187	CDD:409353
		Ig strand E	211..215	CDD:409353
		Ig strand F	225..230	CDD:409353
		Ig strand G	242..245	CDD:409353	1/2 (50%)
		Ig_3	253..320	CDD:464046	15/82 (18%)
		Ig_3	337..406	CDD:464046	23/75 (31%)
		Ig_2	437..>504	CDD:464026	18/72 (25%)
		Ig	525..635	CDD:472250	20/122 (16%)
		Ig strand B	545..549	CDD:409568	0/3 (0%)
		Ig strand C	558..562	CDD:409568	0/3 (0%)
		Ig strand E	587..591	CDD:409568	0/3 (0%)
		Ig strand F	615..620	CDD:409568	2/4 (50%)
		Ig strand G	628..631	CDD:409568	1/2 (50%)
		Ig_3	639..724	CDD:464046	19/92 (21%)
		FN3	741..848	CDD:238020
LOC108648322	XP_017952078.1	Ig	23..102	CDD:472250	17/89 (19%)
		Ig strand B	40..44	CDD:409410	1/3 (33%)
		Ig strand C	55..59	CDD:409410	0/3 (0%)
		Ig strand E	70..74	CDD:409410	0/3 (0%)
		Ig strand F	84..89	CDD:409410	2/4 (50%)
		Ig strand G	95..98	CDD:409410	0/2 (0%)
		Ig	200..283	CDD:472250	21/90 (23%)
		Ig strand B	211..215	CDD:409411	1/3 (33%)
		Ig strand C	229..233	CDD:409411	0/3 (0%)
		Ig strand E	246..250	CDD:409411	2/10 (20%)
		Ig strand F	260..267	CDD:409411	2/6 (33%)
		Ig strand G	276..279	CDD:409411	0/2 (0%)
		Ig_3	388..462	CDD:464046	18/87 (21%)