DRSC/TRiP Functional Genomics Resources

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Protein Alignment ed and LOC108645196

DIOPT Version :9

Sequence 1:NP_001260013.1 Gene:ed / 33619 FlyBaseID:FBgn0000547 Length:1332 Species:Drosophila melanogaster
Sequence 2:XP_031762431.1 Gene:LOC108645196 / 108645196 -ID:- Length:568 Species:Xenopus tropicalis


Alignment Length:442 Identity:98/442 - (22%)
Similarity:155/442 - (35%) Gaps:87/442 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 ESIDTRENADLTLKCRFNDKYEANDFSFFWTRWTANPAQFDNVAIGE---VQLSSGY-----RLD 100
            |||.....:.:.:.|.|........|:..|.|.|.:.:   |:...:   ..:|.||     |:.
 Frog    35 ESIRALRGSCVEIPCTFTLPRGNKGFNLIWYRETKHSS---NIIFSQQDPSDVSEGYRGRTSRVG 96

  Fly   101 FQPER---GIYDLQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPG---- 158
            .:|..   .|.|:|.....|...:|..:...:.:.....|.....|.||       :||.|    
 Frog    97 NEPNSCSLRINDVQESGTYYPYIHGNCDVISECQRVRVQVSDSPKNATV-------IISDGKKEM 154

  Fly   159 ------NIAV-----ATEDKPMELTCSSIGGSPDPT---ITWYREGSNTPLPATVLKGGTKDQPT 209
                  |:.:     ..|...:||.|.....:|..|   .:||            |.|...:..|
 Frog   155 KEDKAKNVTIKGKKEVKERAALELECHFSDYNPPTTQYSYSWY------------LNGNPVNGET 207

  Fly   210 NATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEATATLNVNYYPR---VEVGPENPLRVERDRTA 271
            ...|.|....|.....|.|.|:|||   |:.......:.|.|.|:   |.:......|.|.|: .
 Frog   208 GRILQINNITESHSGTYSCNVQNRA---GRSNSTGFAVTVMYSPKNVTVVISDGKKERKEDDK-V 268

  Fly   272 KLECNVDAKPKVPNVRWNRNGR--------FISSSLVHTIHRVSVQDAGKYTCIADNGLGKTGEQ 328
            :|.|..||.|...|..|.::.|        ....::..|:.    .|..:::|||.|..|....:
 Frog   269 RLSCLSDANPAADNFIWYKHVRNEPKKRRPEQRQNITVTVG----WDRDRFSCIARNPRGPGKSK 329

  Fly   329 ELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVT---IEWLKENSPDFRYNGDVLTLT 390
            .|.|.:||....|...:..|.:||..:.:.|:.:....|.|   ..|....:|.....|.:|.:.
 Frog   330 ILELQVLYKAKNVTIKRKDEVKEGAALELECHFSDYNPPTTQYSYSWYLNGNPVNGETGRILQIN 394

  Fly   391 SVRADHAGNYICR-------------AVNIMQSQ-GMERSERVGNSTVALLV 428
            ::...|:|.|.|.             ||.:|.:| |:.....:|....|:.|
 Frog   395 NITESHSGTYSCNVQNGAGPSYSPGFAVTLMSTQTGLPMRFILGGGAGAVFV 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
edNP_001260013.1 Ig 50..147 CDD:299845 20/107 (19%)
I-set 146..249 CDD:254352 26/120 (22%)
Ig 168..249 CDD:299845 20/83 (24%)
IGc2 268..323 CDD:197706 15/62 (24%)
Ig_3 341..406 CDD:290638 16/80 (20%)
Ig_2 437..514 CDD:290606
I-set 526..633 CDD:254352
Ig 546..632 CDD:143165
IG_like 654..736 CDD:214653
Ig 656..734 CDD:143165
FN3 741..848 CDD:238020
LOC108645196XP_031762431.1 Ig 29..>116 CDD:416386 18/83 (22%)
FR1 29..53 CDD:409353 5/17 (29%)
Ig strand A 29..33 CDD:409353
Ig strand A' 36..40 CDD:409353 2/3 (67%)
Ig strand B 42..53 CDD:409353 2/10 (20%)
CDR1 54..59 CDD:409353 0/4 (0%)
FR2 60..67 CDD:409353 2/6 (33%)
Ig strand C 60..67 CDD:409353 2/6 (33%)
CDR2 68..89 CDD:409353 4/23 (17%)
Ig strand C' 75..79 CDD:409353 0/3 (0%)
Ig strand D 91..95 CDD:409353 0/3 (0%)
Ig strand E 100..108 CDD:409353 1/7 (14%)
Ig 176..244 CDD:416386 20/82 (24%)
Ig strand B 176..183 CDD:409353 3/6 (50%)
Ig strand C 189..198 CDD:409353 3/20 (15%)
Ig strand C' 201..208 CDD:409353 0/6 (0%)
Ig strand E 211..217 CDD:409353 2/5 (40%)
Ig strand F 220..231 CDD:409353 3/10 (30%)
Ig strand G 233..244 CDD:409353 1/10 (10%)
Ig_2 266..332 CDD:404734 16/70 (23%)
IG 349..418 CDD:214652 14/68 (21%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D35531at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.010

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