DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ed and LOC105945909

DIOPT Version :9

Sequence 1:	NP_001260013.1	Gene:	ed / 33619	FlyBaseID:	FBgn0000547	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_031762429.1	Gene:	LOC105945909 / 105945909	-ID:	-	Length:	275	Species:	Xenopus tropicalis

Alignment Length:	200	Identity:	56/200 - (28%)
Similarity:	81/200 - (40%)	Gaps:	50/200 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   340 VVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLKENSPD-----FRYNGDVLTLTSVRADHAGN 399
            |||.:..:|..|||.||:.|...||||.....|.  |:.|     ....|..:|:|..|...  .
Frog    40 VVISNGRKEFIEGDNVTLSCVCDANPAANNFTWY--NNRDKTLELLEEQGRSITVTVGRGRE--T 100

  Fly   400 YICRAVNIMQSQGMERSERVGNSTVALLVRHRPGQAYITPNKPVVHVGNG------VTL--TCSA 456
            :.|.|.|.:         .:|||....|      |....|....|.:.:|      |||  ||.|
Frog   101 FSCAAGNPL---------GIGNSNALEL------QVLYPPKNVTVSILDGNLDLTNVTLICTCFA 150

  Fly   457 NPPGWPVPQYRWFRDMDGEFSSTQKILAQ-----GPQYSIPKAHLGNEGKYHCHAVNELGIGMMA 516
            .|   .|..|.|:||..|:.::.::..|:     ||:..:          |.|.|.|:||:|..:
Frog   151 RP---AVKNYTWYRDRQGQVTTFEEQSAEITINIGPEKEL----------YFCSATNQLGVGFSS 202

  Fly   517 TIVLE 521
            .:.|:
Frog   203 HVDLQ 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_001260013.1	Ig	50..147	CDD:299845
		I-set	146..249	CDD:254352
		Ig	168..249	CDD:299845
		IGc2	268..323	CDD:197706
		Ig_3	341..406	CDD:290638	22/69 (32%)
		Ig_2	437..514	CDD:290606	25/89 (28%)
		I-set	526..633	CDD:254352
		Ig	546..632	CDD:143165
		IG_like	654..736	CDD:214653
		Ig	656..734	CDD:143165
		FN3	741..848	CDD:238020
LOC105945909	XP_031762429.1	IG	51..121	CDD:214652	24/88 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010