DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ed and LOC103909460

DIOPT Version :9

Sequence 1:	NP_001260013.1	Gene:	ed / 33619	FlyBaseID:	FBgn0000547	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_009293728.2	Gene:	LOC103909460 / 103909460	-ID:	-	Length:	286	Species:	Danio rerio

Alignment Length:	289	Identity:	69/289 - (23%)
Similarity:	117/289 - (40%)	Gaps:	65/289 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 ATEDKPMELTCSSIGGSPD---PTITWYR-----EGSNTPLPATVLKG-----------GTKDQP 208
            |.::..|.::|:.|..:|.   ..:.|.:     :|.|    .|.|..           |.|.|.
Zfish    19 ALQNSTMTISCTFIYPTPGFQIMKVFWNKDQEKYDGEN----FTDLSNYSEYSQRLQYLGDKQQN 79

  Fly   209 TNATLSIIPRREDDGAKYKC---VVRNRAMN-EGKRLEATATLNVNYYPRVEVGPENPLRVERDR 269
            ....||.:..:::....::.   |...:.:. .|.||..|           ::..|:|.||....
Zfish    80 CTVRLSHVTEKDEHDYYFRFTTNVTFGKVIGIPGVRLSVT-----------DLQLESPERVTEGD 133

  Fly   270 TAKLECNVDAK-PKVPNVRWNRNGRFISSSLVH-----TIHRVSVQDAGKYTCIADNGLGKTGE- 327
            :.:|.|..... ...|...|.||    |.:|.:     .|..||.::||:|:|      |..|:
Zfish   134 SVRLTCRSSCNLTDTPTFIWYRN----SHTLTNIGDELNIRSVSRREAGRYSC------GVQGQT 188

  Fly   328 ---QELILDILY-PPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLKENSPDFRYNGDVLT 388
               ..:.|:|.| |...||.:::....|||:|.:.|:..||| |..|.|.|..:.  ..:|.:..
Zfish   189 YISPAVYLNITYAPDTPVISNRSAVIMEGDSVILNCSSNANP-PAEINWYKGKTS--LNSGRIFN 250

  Fly   389 LTSVRADHAGNYICRAVNIMQSQGMERSE 417
            ::.:.:|.:|.|.|||.|   ..|::.|:
Zfish   251 ISKISSDDSGEYKCRARN---EHGVKYSD 276

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_001260013.1	Ig	50..147	CDD:299845
		I-set	146..249	CDD:254352	20/108 (19%)
		Ig	168..249	CDD:299845	19/103 (18%)
		IGc2	268..323	CDD:197706	15/60 (25%)
		Ig_3	341..406	CDD:290638	21/64 (33%)
		Ig_2	437..514	CDD:290606
		I-set	526..633	CDD:254352
		Ig	546..632	CDD:143165
		IG_like	654..736	CDD:214653
		Ig	656..734	CDD:143165
		FN3	741..848	CDD:238020
LOC103909460	XP_009293728.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010