DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ed and LOC103909420

DIOPT Version :9

Sequence 1:	NP_001260013.1	Gene:	ed / 33619	FlyBaseID:	FBgn0000547	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_017211396.1	Gene:	LOC103909420 / 103909420	-ID:	-	Length:	226	Species:	Danio rerio

Alignment Length:	239	Identity:	53/239 - (22%)
Similarity:	91/239 - (38%)	Gaps:	72/239 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   191 SNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAKYK----CVVRNRAMNEGKRLEATATLNVNY 251
            ::.||...::..|:..|            :|.|..|.    |.::      |..::.:.|:.
Zfish     7 ASLPLILVIMTAGSDGQ------------QDWGVNYSSSSVCALK------GSTVKISCTVK--- 50

  Fly   252 YPR-------------VEVGPENPLRVERDRTAKLECNVDAKPKVPNVRWNRNGRFISSSLVHTI 303
            ||.             |..|....|..:.|:|.:::|          ||.:::    :||:  |:
Zfish    51 YPHDHQLRSVYWTKHAVTDGETPDLCSDPDKTGRVQC----------VRADKD----TSSI--TL 99

  Fly   304 HRVSVQDAGKYTC--IADNGLGK-TGEQELILDILYPPMVVIESKTRE-AEEGDTVTIRCNVTAN 364
            ..|:..|...|.|  ..|...|| ||...:.||:     ..::.:|:: ..|||:||:.|..:.:
Zfish   100 TAVTEADKHIYYCRFTTDAEGGKWTGIPGVQLDV-----TDLQVETQQTVVEGDSVTLSCKSSCS 159

  Fly   365 -PAPVTIEWLKENSPDFRYNGDVLT-----LTSVRADHAGNYIC 402
             |...|..|.:...   ..|..:.|     |.||....||:|.|
Zfish   160 LPEETTFIWYRNTK---TINKGIRTKNQLHLWSVSYYDAGDYQC 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_001260013.1	Ig	50..147	CDD:299845
		I-set	146..249	CDD:254352	10/61 (16%)
		Ig	168..249	CDD:299845	10/61 (16%)
		IGc2	268..323	CDD:197706	13/56 (23%)
		Ig_3	341..406	CDD:290638	19/69 (28%)
		Ig_2	437..514	CDD:290606
		I-set	526..633	CDD:254352
		Ig	546..632	CDD:143165
		IG_like	654..736	CDD:214653
		Ig	656..734	CDD:143165
		FN3	741..848	CDD:238020
LOC103909420	XP_017211396.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010