DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ed and LOC103909419

DIOPT Version :9

Sequence 1:NP_001260013.1 Gene:ed / 33619 FlyBaseID:FBgn0000547 Length:1332 Species:Drosophila melanogaster
Sequence 2:XP_009293431.2 Gene:LOC103909419 / 103909419 -ID:- Length:517 Species:Danio rerio


Alignment Length:439 Identity:105/439 - (23%)
Similarity:172/439 - (39%) Gaps:120/439 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    34 VALSSTTLADESIDTRENAD-LTLKCRFNDKYEANDFSFFWTRWTANPAQFDNVAIGEVQLSSGY 97
            |.|..|.|..|:..|....| :||.|:.:... ..:.:|.|:|.|..             ::.|.
Zfish   129 VQLDVTDLQVETQQTVVEGDSVTLSCKSSCSL-PEETTFIWSRNTKT-------------INEGI 179

  Fly    98 RLDFQPERGIYDLQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPG---- 158
            |...|       ||:.:|. ..|.|.::|.:     |.:.|               :|||.    
Zfish   180 RTKNQ-------LQLWSVR-GSDAGYYQCAV-----GGNEH---------------LISPAVYVK 216

  Fly   159 ----------------NIAVATEDKPMELTCS---SIGG-------SPDPTITWYREGSNTP--L 195
                            :...|.:...::::|:   |:.|       |..|.:|    |...|  .
Zfish   217 VGRVYGLWKSGVNYSPSYVCALKGSTVKISCTSTYSVYGYQLIQSVSTKPAVT----GEEPPDLC 277

  Fly   196 PATVLKGG----TKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNE-----GKRLEATATLNVNY 251
            ..|.::||    ::|:.| ..:::....|.|...|.|..|:...|.     |.||:.| .|.|..
Zfish   278 TDTDIRGGIQCVSEDKNT-LIITLTAVTEADKHIYYCRFRDTQNNRWTVIPGARLDVT-DLQVET 340

  Fly   252 YPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNVRWNRN-----GRFISSSLVHTIHRVSVQDA 311
            ...|:.|....|      :.|..|::   |:.....|.||     |..:::.|  .:..||..||
Zfish   341 KQCVKEGDSVTL------SCKSSCSL---PEETTFIWYRNTERLTGETLNNQL--QLQSVSHSDA 394

  Fly   312 GKYTCIADNGLGKTGEQ----ELILDILYPPMVVIESKTREA--EEGDTVTIRCNVTANPAPVTI 370
            |:|.|.|   .||.||:    .:.|.:.|||..|..|.:..|  ..||:||:.|:..:||..:..
Zfish   395 GEYRCAA---RGKAGERLNSPPVYLSVEYPPKSVSVSVSGSAVIVSGDSVTLSCSSNSNPPALNF 456

  Fly   371 EWLKENSPDFRYNGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERV 419
            ..||:.:.  ..:|.:.:::::.:||:|.|.|||.|   ..|.:.|:.|
Zfish   457 SRLKDETS--VGSGRIFSISNISSDHSGEYKCRARN---KHGEKHSDPV 500

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
edNP_001260013.1 Ig 50..147 CDD:299845 19/97 (20%)
I-set 146..249 CDD:254352 28/143 (20%)
Ig 168..249 CDD:299845 24/101 (24%)
IGc2 268..323 CDD:197706 16/59 (27%)
Ig_3 341..406 CDD:290638 20/66 (30%)
Ig_2 437..514 CDD:290606
I-set 526..633 CDD:254352
Ig 546..632 CDD:143165
IG_like 654..736 CDD:214653
Ig 656..734 CDD:143165
FN3 741..848 CDD:238020
LOC103909419XP_009293431.2 Ig 30..134 CDD:325142 2/4 (50%)
ig 137..202 CDD:278476 19/86 (22%)
IG_like 344..407 CDD:214653 21/76 (28%)
Ig_2 438..504 CDD:316418 21/68 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D35531at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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