DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ed and LOC101884710

DIOPT Version :9

Sequence 1:NP_001260013.1 Gene:ed / 33619 FlyBaseID:FBgn0000547 Length:1332 Species:Drosophila melanogaster
Sequence 2:XP_009298712.1 Gene:LOC101884710 / 101884710 -ID:- Length:479 Species:Danio rerio


Alignment Length:500 Identity:93/500 - (18%)
Similarity:171/500 - (34%) Gaps:151/500 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 CNFFLIALVALSSTTLADESIDTRENADLTLKCRFN-------------------DKYEANDFSF 71
            |..|.|:|         .|.|.....:.:.:||||:                   |:::.:....
Zfish    19 CRDFSISL---------PEKIQALSGSCVIIKCRFDIKESYDKDLTERAAGVWYKDRHDKSSSIV 74

  Fly    72 FWTRWTANPAQFDNVAI-GEVQLSSGYRLDFQPERGIYDLQIKNVSYNRDNGRFECRIKAKG--- 132
            |     .:.|...|..| |.:   :|..:|.......||:.      :..:|::..||:::|   
Zfish    75 F-----NSSASTQNFFIKGNI---TGQLIDKDCTTVFYDVT------SNHSGQYFFRIESEGELR 125

  Fly   133 -------TGADVHQEFHNLTVLTPPHPPVISPG----NIAVATEDKPMELTCS--SIGGSPDPTI 184
                   ...||.:...|      |...:...|    :.....|.:.:.|.||  ::..||..|:
Zfish   126 WTYKENSVSVDVIETLEN------PRVVLYVDGQELQDQQKVFEGRSVSLRCSAKTLCSSPPATL 184

  Fly   185 TWYREGSNTPLPATVLKGGTKDQPTN------ATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEA 243
            ||   .|...:|        ..:..|      :.|:....:......:.|.:..:..:..|...:
Zfish   185 TW---SSTARIP--------HSESINLKELIISDLNFTAAQRHHRVTFTCSISYQLQDNNKTANS 238

  Fly   244 TATLNVNYYPRVEVGPENPLRVERDRTAKLECNVDAKPKVPNVRWNRNGRFISSS---------L 299
            :.||:|.|.|::    .|......|.|... |.||..|. |.|.|:.:|..:|:|         |
Zfish   239 SITLHVQYAPQI----SNSSCSSTDVTVCF-CEVDGNPS-PEVEWHLSGCPVSNSSNTLISEERL 297

  Fly   300 VHTIHR--VSVQDAGKYT----CIADNGLGKTGEQ--------------------ELILDILYP- 337
            .:|..|  :|:..:..:|    |::.|..|.:..|                    .|::.:|:. 
Zfish   298 SNTSLRSFISLHQSLTHTNTLLCVSKNTRGASTLQFHLVFVPQKEIYILIGAAAGALVIVLLWAV 362

  Fly   338 --PMVVIESKTRE------AEEGDTVTIRCNVTANPAPVTIEWLKENSPDFRYNGDVLTLTSVRA 394
              ....:..|..|      .|||             |..::|...|.:.|...|..:::......
Zfish   363 TYAYTCVRRKNNEKIQPTNQEEG-------------ANESVENTDEENQDDSANNVIISSAGATT 414

  Fly   395 DHAGNYICRAVNIMQSQGMERSERVGNSTVAL----LVRHRPGQA 435
            .:..:.|..:::...|:  .||::|.:.:..|    :|:|..|.|
Zfish   415 ANQKSIIYSSIDFSNSE--SRSQQVVSVSCLLADYAVVQHGSGGA 457

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
edNP_001260013.1 Ig 50..147 CDD:299845 21/126 (17%)
I-set 146..249 CDD:254352 19/114 (17%)
Ig 168..249 CDD:299845 16/88 (18%)
IGc2 268..323 CDD:197706 19/69 (28%)
Ig_3 341..406 CDD:290638 11/70 (16%)
Ig_2 437..514 CDD:290606
I-set 526..633 CDD:254352
Ig 546..632 CDD:143165
IG_like 654..736 CDD:214653
Ig 656..734 CDD:143165
FN3 741..848 CDD:238020
LOC101884710XP_009298712.1 Ig 22..137 CDD:299845 23/137 (17%)
IG_like 158..244 CDD:214653 17/96 (18%)
Ig 163..230 CDD:299845 14/77 (18%)
Ig 244..338 CDD:299845 25/99 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D35531at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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