DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ed and zmp:0000000650

DIOPT Version :9

Sequence 1:NP_001260013.1 Gene:ed / 33619 FlyBaseID:FBgn0000547 Length:1332 Species:Drosophila melanogaster
Sequence 2:XP_017210802.1 Gene:zmp:0000000650 / 100538209 ZFINID:ZDB-GENE-130530-653 Length:577 Species:Danio rerio


Alignment Length:398 Identity:95/398 - (23%)
Similarity:155/398 - (38%) Gaps:80/398 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 ESIDTRENADLTLKCRFN-----DKY--EANDFSFFWTRWTANPAQFDNVAIGEVQLSSGYRLD- 100
            |.|:....:.:.::|||.     |||  |.|...|::.            ...||..|..::.| 
Zfish    28 EKIEALSGSCVIIECRFEIVPEMDKYLTEENAVGFWFN------------GKKEVFHSKHHKADH 80

  Fly   101 FQ--PERGIYDLQIKNVSYN---RDNGRFECRIKAKGTGADV----HQEFHNLTVLTPPHPPVIS 156
            |:  ....:::.....|.||   ..|.:|..||::...|..:    :::...:.|:..|..|.| 
Zfish    81 FEGTMSEKLHEKNCTTVFYNVGSDHNNKFYFRIESTVNGIGLKYSYNKKLSTINVVESPVNPRI- 144

  Fly   157 PGNIAVATED-------------KPMELTCS--SIGGSPDPTITWYREGSNTPLPATVLKGGTKD 206
                 |..||             :.:.|.||  ::...|..|:||...|.      .:|...:|.
Zfish   145 -----VLYEDEQELQDQQEVLEGRSVSLRCSAETLCSIPPATLTWSSAGK------ILLSESSKL 198

  Fly   207 QP---TNATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEATATLNVNYYPR---VEVGPENPLRV 265
            |.   :....:..||..  ...:.|.:..:..:..|...::..|:|.|.|:   |.|.|.|.:.|
Zfish   199 QELVVSALNFTAAPRHH--RVTFTCSISYQLQDNNKTARSSIPLHVQYSPKNTSVSVFPSNSVLV 261

  Fly   266 ERDRTAKLECNVDAKPKVPNVRWNRNGR----FISSSLVHTIHRVSVQDAGKYTCIADNGLGKTG 326
            ....|  |.|:.:|.|.|....|:|..:    .:.:....|.:..::..:|.|.|.|.|..| |.
Zfish   262 GHSVT--LTCSSEANPAVLIYSWSRETKGQLEMLQTGETLTFNETALSHSGLYICTAQNKHG-TQ 323

  Fly   327 EQELILDILYPPMVVIESKTREAEEGDTVTIRCNVTANPAPVTIEW-----LKENSPDFRYNGDV 386
            .:.::|||.|.|.  |.|.:.....|.|... |.|..||.| .:||     |..|||:...:...
Zfish   324 TKAVMLDIQYVPQ--ISSSSSCTSTGVTECF-CEVDGNPYP-EVEWHLSGHLVSNSPNTFISEKR 384

  Fly   387 LTLTSVRA 394
            |:.||:|:
Zfish   385 LSNTSLRS 392

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
edNP_001260013.1 Ig 50..147 CDD:299845 22/113 (19%)
I-set 146..249 CDD:254352 23/120 (19%)
Ig 168..249 CDD:299845 16/85 (19%)
IGc2 268..323 CDD:197706 14/58 (24%)
Ig_3 341..406 CDD:290638 19/59 (32%)
Ig_2 437..514 CDD:290606
I-set 526..633 CDD:254352
Ig 546..632 CDD:143165
IG_like 654..736 CDD:214653
Ig 656..734 CDD:143165
FN3 741..848 CDD:238020
zmp:0000000650XP_017210802.1 Ig 22..126 CDD:299845 24/109 (22%)
Ig 152..228 CDD:299845 14/83 (17%)
IG_like 255..329 CDD:214653 19/76 (25%)
IGc2 262..321 CDD:197706 14/60 (23%)
Ig 353..415 CDD:299845 15/41 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D35531at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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