DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ed and zmp:0000000971

DIOPT Version :9

Sequence 1:NP_001260013.1 Gene:ed / 33619 FlyBaseID:FBgn0000547 Length:1332 Species:Drosophila melanogaster
Sequence 2:XP_017211417.2 Gene:zmp:0000000971 / 100332786 ZFINID:ZDB-GENE-130530-974 Length:428 Species:Danio rerio


Alignment Length:428 Identity:94/428 - (21%)
Similarity:151/428 - (35%) Gaps:107/428 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 GTAIVNSRSARRAATTICNFFLIALVALSST----TLADESIDTRENADLTLKCRFNDKYEAND- 68
            |.|:|.|   .|....:...||:.:...|||    ..:...|...:|:.:|:.|.:.  |.|.. 
Zfish     7 GVAMVMS---IRMTPPLPLIFLLIVHGGSSTEWNVKYSPSHICALKNSSVTMSCTYT--YPAGHQ 66

  Fly    69 -FSFFWTRWT--ANPAQFDNVAI-----------GEVQLSSGYRLDF---QPERGIYDLQIKNVS 116
             .:.|||:.|  .:..:|.::::           |:.|.:...||..   :.||..|...|.:  
Zfish    67 IKNVFWTKTTDKRDDEEFPDLSVDPEYSQRLQYLGDNQQNCTVRLSHVTKEDERMYYFRFITD-- 129

  Fly   117 YNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPGNIAVATEDKPMELTC-SSIGGSP 180
               .||::..:|..:.:..|:..|               ||..:   ||...:.||| ||...:.
Zfish   130 ---KNGKWIGKIGVRLSVTDLQLE---------------SPERV---TEGDSVRLTCRSSCKLTD 173

  Fly   181 DPTITWYREGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMNEGKRLEATA 245
            .||..|||.....            .:.|...|.:.|.|.:|..:|:|.|....:.     ....
Zfish   174 TPTFIWYRNSQRL------------TEKTIEKLILDPVRREDAGRYRCAVHGHTLT-----SPDI 221

  Fly   246 TLNVNYYPR-VEVGPENPLRVERDRTAKLECNVDAKPKVPNVRWNRNGRFISSSLVHTIHRVSVQ 309
            .|||.|.|| |.|.......:....:..|.|..|:.|...|..|....:   ||.|.:....|..
Zfish   222 NLNVTYPPRNVSVSINGSAEIVSGDSVGLMCISDSNPPALNFSWFEENQ---SSAVGSGQSFSAV 283

  Fly   310 DAGKYTCIADNGLGKTGEQELILDILYPPMV----------------------VIESKTREAEE- 351
            .:|::.|.|.|..|......:.:.:..||::                      :...|.|:|:: 
Zfish   284 QSGRFYCEAHNPHGAQRSDAVTVTVKGPPVLFYISIGVVCGAAVFITKGIIWGIRRMKERKAKQQ 348

  Fly   352 ------GDTVTIRCNVTANPAPVTIEWLKENSPDFRYN 383
                  .|.....|:|..| .||     .||:..|:.|
Zfish   349 QNPSRHQDDKRKACDVDLN-QPV-----YENATAFQIN 380

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
edNP_001260013.1 Ig 50..147 CDD:299845 23/114 (20%)
I-set 146..249 CDD:254352 23/103 (22%)
Ig 168..249 CDD:299845 19/81 (23%)
IGc2 268..323 CDD:197706 14/54 (26%)
Ig_3 341..406 CDD:290638 13/50 (26%)
Ig_2 437..514 CDD:290606
I-set 526..633 CDD:254352
Ig 546..632 CDD:143165
IG_like 654..736 CDD:214653
Ig 656..734 CDD:143165
FN3 741..848 CDD:238020
zmp:0000000971XP_017211417.2 V-set 52..145 CDD:311561 20/99 (20%)
IG_like 151..225 CDD:214653 23/93 (25%)
Ig_2 236..308 CDD:316418 15/74 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D35531at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.010

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