Protein Alignment ed and kirrel1b

DIOPT Version :9

• Sequence 1: NP_001260013.1
• Gene: ed / 33619
• FlyBaseID: FBgn0000547
• Length: 1332
• Species: Drosophila melanogaster
• Sequence 2: XP_017212964.1
• Gene: kirrel1b / 100170816
• ZFINID: ZDB-GENE-070912-173
• Length: 801
• Species: Danio rerio
• Alignment Length: 856
• Identity: 198/856 - (23%)
• Similarity: 307/856 - (35%)
• Gaps: 260/856 - (30%)

  Fly    42 ADESIDTRENADLTLKCRFNDKYEANDFSFFWT---RWTANPAQFDNVAIG---EVQLSSGYRLD 100
            ||:|:...|.  :.|.|          ..|.:|   :||.     |.:|:|   :::....||:.
Zfish    32 ADQSVVIGER--VVLSC----------VVFNYTGIVQWTK-----DGLALGIGEDLRAWPRYRVL 79

  Fly   101 FQPERGIYDLQIKNVSYNRDNGRFECRIKAKGTGADVHQEFHNLTVLTPPHPPVISPGNIAVATE 165
            ...:.|.|:|:|.:.... |:..:||    :.|.|.:......||||.||..|||......:.|.
Zfish    80 RIMDVGQYNLEITSADLT-DDSLYEC----QATEAALRSRRAKLTVLIPPDGPVIEGSPEILLTA 139

  Fly   166 DKPMELTCSSIGGSPDPTITWYR-----EGSNTPLPATVLKGGTKDQPTNATLSIIPRREDDGAK 225
            .....|||.|.|..|..||.||:     ||::|   :|.:....|...|.:.|.|.|...|.|..
Zfish   140 GTSFNLTCVSRGAKPMSTIEWYKDGIIVEGAHT---STEVLSDRKRVTTKSFLEIQPMDTDTGRN 201

  Fly   226 YKCVVRNRAMNEGKRLEATATLNVNYYPRV--EVGPENPLRVERDRTAKLECNVDAKPKVPNVRW 288
            :.||..|.|...|||  :|.|||:::.|.|  .:.|.:.|..||   .|..|...|.|.:...||
Zfish   202 FTCVASNLAAPLGKR--STVTLNIHHPPTVILSIEPRSVLEGER---VKFTCQATANPPIMGYRW 261

  Fly   289 NRNGRFISSSLVHTIHRVSV----QDAGKYT----CIADNGLGKTGEQELILDILYPPMVVIESK 345
            .:.|..:..:      |.||    .|...:|    |:..|.:|.| ...:::|:.:.|::|:|.:
Zfish   262 AKGGVILDGA------RESVFETTADHSFFTEPVSCLVFNAVGST-NVSILVDVHFGPILVVEPR 319

  Fly   346 TREAEEGDTVTIRCNVTANPAPVTIEWLKENSPDFRYNGDVLTLTSVRADHAGNYICRAVNIMQS 410
            ....:....||:.|..:.|| |:|:.|.|:.|.....|.:.|.|.||....||.|:|:|  |:..
Zfish   320 PVTVDVDSDVTLNCKWSGNP-PLTLTWTKKGSSMVLSNSNQLFLKSVSQADAGQYVCKA--IVPR 381

  Fly   411 QGMERSERVGNSTVALLVRHRPGQAYITPNKPVVHV--GNGVTLTC---SANPPG---WPVPQYR 467
            .|      ||.:.|.|.|...|    |..::|:.:.  |....:.|   |..||.   |...:..
Zfish   382 IG------VGETEVTLTVNGPP----IISSEPIQYAVRGEKGEIKCYIASTPPPDKIVWAWKENV 436

  Fly   468 WFRD-------------------------------MDGEFSSTQKILAQGPQYSIPKAHLGNEGK 501
            |.::                               |:.:|.||
Zfish   437 WEKERGTLLERYTVEQSRPATQGGAVLSTLTINNVMEADFQST---------------------- 479

  Fly   502 YHCHAVNELGIGMMATIVLEIHQPPQFLAKLQQHMTRRVADTDYT-VTCSAKGKPAPSV------ 559
            |:|.|.|..|.|.| .|.||               ...:|..|.. |...|.|....|:
Zfish   480 YNCTAWNAFGPGTM-IITLE---------------ETDIASEDIVPVGVIAGGSVGSSILLLLLL 528

  Fly   560 -----------KWLKDAVEILPEENLYEVQTNPDQGLNGMVTVQSQLKFRGKARPNGNALVPGDR 613
                       |..:..|.:.|:   .:|:|         |..::.|:....:......:|   :
Zfish   529 FALIFYLYRQRKSSRRGVTLKPD---IKVET---------VNKETNLEEEAASASTATRMV---K 578

  Fly   614 GLYTCLYQNEVNSANSSMQLRIEHEPIVLHQYNKVAFDIR---ETAEVVCKVQAYPKPEFQWQFG 675
            .:|:.|         .|:.|....:|.      |...|::   :|..:..||:.|...:
Zfish   579 AMYSFL---------PSVSLSPSTQPF------KDDMDLKQDLQTETLEPKVEEYEAKD------ 622

  Fly   676 NNPSPLTMSSDGHYEISTTTDNNDIYTSVLKINSLTHSDY-----------------------GE 717
                    .::|:|.:..|| ::::.:|.   .||.:.::                       |.
Zfish   623 --------PTNGYYNVRATT-HDEVRSST---RSLLYQEFRAPNPASVSASTGGPANIHPAPTGR 675

  Fly   718 Y----TCRVA-NTLDTIRAPIRLQQKGPPEKPTNLRATEVGHNYVSLSWD-PGFDGGLSKTK--F 774
            |    |.|:| ||........|..|..||..|            ||.:.| |...|.|..|.  .
Zfish   676 YEARPTSRMAHNTYAHFNTIARASQIQPPANP------------VSKTTDYPAERGLLESTNPLA 728

  Fly   775 FVSYRRVAMPR 785
            |.||.....|:
Zfish   729 FDSYAYSTTPQ 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_001260013.1	Ig	50..147	CDD:299845	23/102 (23%)
		I-set	146..249	CDD:254352	39/107 (36%)
		Ig	168..249	CDD:299845	31/85 (36%)
		IGc2	268..323	CDD:197706	14/62 (23%)
		Ig_3	341..406	CDD:290638	22/64 (34%)
		Ig_2	437..514	CDD:290606	18/115 (16%)
		I-set	526..633	CDD:254352	17/124 (14%)
		Ig	546..632	CDD:143165	15/103 (15%)
		IG_like	654..736	CDD:214653	19/109 (17%)
		Ig	656..734	CDD:143165	17/105 (16%)
		FN3	741..848	CDD:238020	13/48 (27%)
kirrel1b	XP_017212964.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170582422
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840