DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ed and LOC100150177

DIOPT Version :9

Sequence 1:	NP_001260013.1	Gene:	ed / 33619	FlyBaseID:	FBgn0000547	Length:	1332	Species:	Drosophila melanogaster
Sequence 2:	XP_017212278.1	Gene:	LOC100150177 / 100150177	-ID:	-	Length:	491	Species:	Danio rerio

Alignment Length:	366	Identity:	85/366 - (23%)
Similarity:	143/366 - (39%)	Gaps:	82/366 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   203 GTKDQPTNATLSIIPRREDDGAKYKCVVRNRAMN----EGKRLEATATLNVNYYPRVEVGPENPL 263
            |.|.:.....||.:.::::....::.|.......    .|.||..|           ::..|:|.
Zfish    91 GDKQENCTVRLSHVTKKDEHVYYFRFVTNVEGQKWIGIPGVRLSVT-----------DLQLESPE 144

  Fly   264 RVERDRTAKLECNVDAK-PKVPNVRWNRNGRF---ISSSLVHTIHRVSVQDAGKYTCIADNGLGK 324
            ||....:.:|.|....| ...|...|.||...   |...|  .|..||.::||.|:|      |.
Zfish   145 RVTEGDSVRLTCKSSCKLTDTPTFIWYRNSHILTNIGDEL--NIRSVSRREAGHYSC------GV 201

  Fly   325 TGE----QELILDILYPP--MVVIESKTREAEEGDTVTIRCNVTANPAPVTIEWLK-ENSPDFRY 382
            .|:    ..:.|::.|.|  .|:..|.:....|||:||:.|:..:|| |..|.|.| |.|..
Zfish   202 QGQTYISPAVYLNVTYAPDTPVISISGSAVIMEGDSVTLSCSSDSNP-PAQISWFKGETSVG--- 262

  Fly   383 NGDVLTLTSVRADHAGNYICRAVNIMQSQGMERSERVGNSTVALLVRHRP--------GQAYITP 439
            :|.:..::.:.:|.:|.|.|.|.|       :..|:: :..|.|.|::.|        |.|.|..
Zfish   263 SGRIFNISKISSDDSGEYKCSARN-------DHGEKI-SDPVTLDVQYPPKSISVSISGSAVIMS 319

  Fly   440 NKPVVHVGNGVTLTC--SANPPGWPVPQYRWFRDMDGEFSSTQKILAQGPQYSIPKAHLGNEGKY 502
            ...:  ..:.|:|.|  .:|||..   .:.||::      :....:..|..:|..::     |::
Zfish   320 GDSL--FSDSVSLMCISDSNPPAL---SFSWFKE------NQSSAVGSGQSFSAVQS-----GRF 368

  Fly   503 HCHAVNELGIGMMATIVLEIHQPPQFLAKLQQHMTRRVADT 543
            :|.|.|..|......:.:.:          |||..|.:..|
Zfish   369 YCEAHNPHGAQRSDAVTVTV----------QQHAVRNIVIT 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_001260013.1	Ig	50..147	CDD:299845
		I-set	146..249	CDD:254352	9/49 (18%)
		Ig	168..249	CDD:299845	9/49 (18%)
		IGc2	268..323	CDD:197706	16/58 (28%)
		Ig_3	341..406	CDD:290638	21/65 (32%)
		Ig_2	437..514	CDD:290606	16/78 (21%)
		I-set	526..633	CDD:254352	5/18 (28%)
		Ig	546..632	CDD:143165
		IG_like	654..736	CDD:214653
		Ig	656..734	CDD:143165
		FN3	741..848	CDD:238020
LOC100150177	XP_017212278.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010