Protein Alignment ed and nectin1a

DIOPT Version :10

• Sequence 1: NP_523469.2
• Gene: ed / 33619
• FlyBaseID: FBgn0000547
• Length: 1332
• Species: Drosophila melanogaster
• Sequence 2: XP_005161186.2
• Gene: nectin1a / 100136836
• ZFINID: ZDB-GENE-090224-1
• Length: 496
• Species: Danio rerio
• Alignment Length: 340
• Identity: 73/340 - (21%)
• Similarity: 128/340 - (37%)
• Gaps: 95/340 - (27%)

  Fly   446 VGNGVTLTC---SANPPGWPVPQYRWFRDMDGEFSSTQKILAQGPQYSIP--------------- 492
            ||:.|.|.|   ::||| ..:.|..|.:.::|   :.|.:....|...:.
Zfish    33 VGSQVELPCQFVNSNPP-VKISQVTWQKLVNG---TKQNVAIANPALGVSVLNPFRERVRFKNPA 93

  Fly   493 ----------------KAHLGNEGKYHC--------HAVNELGIGMMATIVLEIH-QPPQFLAKL 532
                            :..|.:|..|.|        :..|.:.:.:.|..::::. ..|..:|..
Zfish    94 VRQRTPSLEDTTIVFNRLKLTDESTYICEYTTFPAGNRENMVNLTVFARPMIQMSLSTPSIVAGS 158

  Fly   533 QQHMTRRVADTDYTV-TC-SAKGKPAPSVKWLKDAVEILPEENLYEVQTNPDQGLNGMVTVQSQL 595
            :        |...|| || ||.||||..:.|..|   :..|.|..|: :|||    |.|||:|..
Zfish   159 K--------DLKMTVATCVSANGKPASVITWETD---LDGESNTQEI-SNPD----GTVTVRSDY 207

  Fly   596 KFRGKARPNGNALVPG---DRGLYTCLYQNEVNSANSSMQLRIEHEP-IVLHQYNKVAFDIRETA 656
                       .:||.   .:.|.||:..........|:.|.|::|| :::..::...:..||..
Zfish   208 -----------LVVPSREIHQQLLTCISTYNDEQYTDSVTLNIQYEPEVIIEGFDGNWYLNRENV 261

  Fly   657 EVVCKVQAYPKPE-FQWQFGNNPSPLTMSSDGHYEISTTTDNNDIYTSVLKINSLTHSDYGEYTC 720
            ::.|...|.|... :||::.|...|           |:....:|:.  :.| ..:|:...|.|.|
Zfish   262 QLTCLADANPTISLYQWRYLNGTLP-----------SSAELRDDVL--IFK-GPVTYDIAGTYVC 312

  Fly   721 RVANTLDTIRAPIRL 735
            ...|::.:..|.:.:
Zfish   313 DATNSIGSGSASVEV 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ed	NP_523469.2	V-set	50..147	CDD:462230
		Ig	153..249	CDD:472250
		Ig strand B	169..173	CDD:409353
		Ig strand C	183..187	CDD:409353
		Ig strand E	211..215	CDD:409353
		Ig strand F	225..230	CDD:409353
		Ig strand G	242..245	CDD:409353
		Ig_3	253..320	CDD:464046
		Ig_3	337..406	CDD:464046
		Ig_2	437..>504	CDD:464026	16/91 (18%)
		Ig	525..635	CDD:472250	33/114 (29%)
		Ig strand B	545..549	CDD:409568	2/4 (50%)
		Ig strand C	558..562	CDD:409568	0/3 (0%)
		Ig strand E	587..591	CDD:409568	2/3 (67%)
		Ig strand F	615..620	CDD:409568	3/4 (75%)
		Ig strand G	628..631	CDD:409568	0/2 (0%)
		Ig_3	639..724	CDD:464046	17/86 (20%)
		FN3	741..848	CDD:238020
nectin1a	XP_005161186.2	None