Protein Alignment fred and MET7

DIOPT Version :9

• Sequence 1: NP_608812.3
• Gene: fred / 33613
• FlyBaseID: FBgn0051774
• Length: 1447
• Species: Drosophila melanogaster
• Sequence 2: NP_014884.1
• Gene: MET7 / 854415
• SGDID: S000005767
• Length: 548
• Species: Saccharomyces cerevisiae
• Alignment Length: 542
• Identity: 96/542 - (17%)
• Similarity: 171/542 - (31%)
• Gaps: 229/542 - (42%)

  Fly   168 EGSTVPLQSYALKGGSKNH------YTNATLQIV---------PRRADDGAKYKCVVWNRAMPEG 217
            :|||....| ::.|..|..      ||:..|:.|         |...:..|||...||:|.
Yeast   131 KGSTAAFTS-SILGQYKEQLPRIGLYTSPHLKSVRERIRINGEPISEEKFAKYFFEVWDRL---- 190

  Fly   218 HMLETSVTLNVNYYPRVEVGPQNPLKVERDHVAKLDCRVDAKPMVSNVRWSRNG--QYVSATPTH 280
                .|.|.:::.:|.:..|                              |:.|  ::::....|
Yeast   191 ----DSTTSSLDKFPHMIPG------------------------------SKPGYFKFLTLLSFH 221

  Fly   281 TIYRVNRHHAGKYTCSADNGLGKTGEKDIVLDVLYPPI---VFIESKTHEAEEGETVLIRCNVTA 342
            |..:.:..     :|..:.|:|  ||.|.. :::..||   |.:....|....|:|:
Yeast   222 TFIQEDCK-----SCVYEVGVG--GELDST-NIIEKPIVCGVTLLGIDHTFMLGDTI-------- 270

  Fly   343 NPSPINVEW-----LKEGAPDF---RYTGELLTLGSVRAEHAGNYICRSVNIMQ--PFSSKRVEG 397
                ..:.|     .|.|||.|   :...:.||:...|||.      |...:.:  ||  |::|.
Yeast   271 ----EEIAWNKGGIFKSGAPAFTVEKQPPQGLTILKERAEE------RKTTLTEVPPF--KQLEN 323

  Fly   398 V----------GNSTVALLVRHRPGQAYITPNKPVVHVGNGV--TLTCSANPPGWPVPQYRWFRD 450
            |          .|:::|:::.           ..::|..|.:  .:.||:|.   .:|:
Yeast   324 VKLGIAGEFQKSNASLAVMLA-----------SEILHTSNILEEKIKCSSNA---SIPE------ 368

  Fly   451 MDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIGKIATIILEVHQPPQFLAKLQQHM 515
                            ::.|...:...||:  |..:.:   ||....|...|..
Yeast   369 ----------------KFIIGLQNTKWEGR--CQVLEK---GKNVWYIDGAHTK----------- 401

  Fly   516 TRRVGDVDYAVTCSAKGKPTPQIRWIKDGTEILPTRKMFDIRTTPTDAGGGVVAVQSILRFRGKA 580
                   |..|..|.         |.:|...:...:|                    ||.|..::
Yeast   402 -------DSMVAAST---------WFRDMVRLSKRKK--------------------ILLFNQQS 430

  Fly   581 RPNGNQLLPNDRGLYTCL---------------------YENDVNSANSSMH----LRIEHEPIV 620
            | :.|.|:.|   ||:.:                     |..|:.|.|:|..    |:::..  :
Yeast   431 R-DANALVNN---LYSSVSPEITFDDVIFTTNVTWKSGSYSADLVSMNTSQEDVEKLKVQES--L 489

  Fly   621 IHQYNKVAYDLRESAEVVCRVQ 642
            :..:||:. |.|....|...::
Yeast   490 VKNWNKID-DNRAKTHVTASIE 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653	19/74 (26%)
		Ig	147..228	CDD:299845	19/74 (26%)
		I-set	232..313	CDD:254352	12/82 (15%)
		IGc2	250..302	CDD:197706	6/53 (11%)
		IG_like	323..385	CDD:214653	15/69 (22%)
		IGc2	330..385	CDD:197706	14/62 (23%)
		Ig_2	416..501	CDD:290606	13/86 (15%)
		IG_like	418..501	CDD:214653	13/84 (15%)
		I-set	505..612	CDD:254352	20/131 (15%)
		Ig	526..611	CDD:143165	19/105 (18%)
		IG_like	633..715	CDD:214653	1/10 (10%)
		Ig	635..713	CDD:143165	1/8 (13%)
		FN3	720..838	CDD:238020
MET7	NP_014884.1	folC	100..542	CDD:273659	96/542 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0285
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900