Sequence 1: | NP_608812.3 | Gene: | fred / 33613 | FlyBaseID: | FBgn0051774 | Length: | 1447 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_004637.1 | Gene: | NPHS1 / 4868 | HGNCID: | 7908 | Length: | 1241 | Species: | Homo sapiens |
Alignment Length: | 1106 | Identity: | 219/1106 - (19%) |
---|---|---|---|
Similarity: | 371/1106 - (33%) | Gaps: | 340/1106 - (30%) |
- Green bases have known domain annotations that are detailed below.
Fly 6 LLIIGQL-----WLSI------GLISGDDSLDTREGVDLVLKCRFTEHYDSTDFTFYWARWTCCP 59
Fly 60 TLFENVAIG-DVQLNS--NYRLDFRPSRGIYDLQIKNTSYNRDNGRFECRIKAKGTGADVHQEFY 121
Fly 122 NLTVLTAPHPPMVTP--GNLAVATEEKPLELTCSSIGGSPDPMITWYREGSTV-PLQSYALKGGS 183
Fly 184 KNHYT-NATLQIVPRRADDGAKYKCVVWNRAMPEGHMLETSVTLNVNYYPRVEVGPQNPL----K 243
Fly 244 VERDHV-----AKLDCRVDAKPMVSNVRWSRNGQYVS-ATPTHTIYRVNR----------HHAGK 292
Fly 293 YTCSADNGLGK-TGEKDIVLDVLYPPIVFIESKTHEAEEGETVLIRCNVTANPSPINVEW----- 351
Fly 352 ----LKEGAPDFRYTGEL----LTLGSVRAEHAGNYICRSVNIMQPFSSKRVEGVGNSTVALLVR 408
Fly 409 HRPGQAYI--TPNKPVVHVGNGVTLTCSANPPGWPVPQYRWFRD--------------------- 450
Fly 451 -MDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIGKI-ATIILEVHQPPQFLAKLQQ 513
Fly 514 HMTRRVGDVDYAVTC-SAKGKPTPQIRWIKDGTEI-----LPTRKMFD---------IRTTPTDA 563
Fly 564 GGGVV----------AVQSILRFRGKARP--------------NGNQLLP--------------- 589
Fly 590 -----------------------------NDRGLYTCLYENDVNSANSSMHLRIEHEPIVIHQYN 625
Fly 626 KVAYDLRESAEVVCRVQAYP--KPEFQW----------------------------------QYG 654
Fly 655 ----------------------------NNPSPLTMSS--------------------------- 664
Fly 665 --------DGHYEISTRMENNDVYTSILRIAHLQHS-DYGEYICRAVNPLDSIRAPIRLQPKGSP 720
Fly 721 EKPTNLKILEVGHNYAVLNWTPGFNGGFMSTKYLVSYRRVATPREQTLSDCSGNGYIPSYQISSS 785
Fly 786 SSNSNHEWIEFNCFKENPCKLAPLDQHQSYMFKVYALNSKGTSGYSNEILATTKVSKIP---PPL 847
Fly 848 H 848 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
fred | NP_608812.3 | Ig | 29..126 | CDD:299845 | 21/99 (21%) |
IG_like | 141..228 | CDD:214653 | 19/88 (22%) | ||
Ig | 147..228 | CDD:299845 | 19/82 (23%) | ||
I-set | 232..313 | CDD:254352 | 26/101 (26%) | ||
IGc2 | 250..302 | CDD:197706 | 16/62 (26%) | ||
IG_like | 323..385 | CDD:214653 | 11/74 (15%) | ||
IGc2 | 330..385 | CDD:197706 | 11/67 (16%) | ||
Ig_2 | 416..501 | CDD:290606 | 22/109 (20%) | ||
IG_like | 418..501 | CDD:214653 | 21/105 (20%) | ||
I-set | 505..612 | CDD:254352 | 33/189 (17%) | ||
Ig | 526..611 | CDD:143165 | 28/167 (17%) | ||
IG_like | 633..715 | CDD:214653 | 30/181 (17%) | ||
Ig | 635..713 | CDD:143165 | 28/177 (16%) | ||
FN3 | 720..838 | CDD:238020 | 24/117 (21%) | ||
NPHS1 | NP_004637.1 | V-set | 38..119 | CDD:284989 | 20/93 (22%) |
IG_like | 38..113 | CDD:214653 | 20/87 (23%) | ||
C2-set_2 | 141..228 | CDD:285423 | 20/88 (23%) | ||
Ig | 240..321 | CDD:299845 | 21/86 (24%) | ||
IG_like | 254..336 | CDD:214653 | 22/81 (27%) | ||
Ig | 345..424 | CDD:299845 | 13/84 (15%) | ||
Ig | 445..530 | CDD:299845 | 18/93 (19%) | ||
I-set | 446..541 | CDD:254352 | 22/109 (20%) | ||
Ig | 549..632 | CDD:299845 | 17/83 (20%) | ||
IG_like | 558..642 | CDD:214653 | 19/84 (23%) | ||
I-set | 646..736 | CDD:254352 | 12/89 (13%) | ||
Ig | 662..736 | CDD:299845 | 11/73 (15%) | ||
Ig_3 | 739..820 | CDD:290638 | 11/80 (14%) | ||
IG_like | 748..821 | CDD:214653 | 10/72 (14%) | ||
Ig8_hNephrin_like | 834..942 | CDD:143250 | 21/108 (19%) | ||
IG_like | 845..935 | CDD:214653 | 19/90 (21%) | ||
fn3 | 942..1023 | CDD:278470 | 21/107 (20%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1025..1057 | 5/21 (24%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1099..1137 | ||||
Binds to NPHS2 | 1160..1241 | ||||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 1 | 0.900 | - | - | E1_KOG3515 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 1 | 1.100 | - | - | O | PTHR11640 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
User_Submission | 0 | 0.000 | Not matched by this tool. | |||
3 | 2.910 |