DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fred and fpgs

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	NP_998602.2	Gene:	fpgs / 406746	ZFINID:	ZDB-GENE-040426-2781	Length:	572	Species:	Danio rerio

Alignment Length:	295	Identity:	63/295 - (21%)
Similarity:	99/295 - (33%)	Gaps:	90/295 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   606 ANSSMHLRIEHEPIVIHQYNKVAYDLRESAEVVCRVQAY-PKP-------EFQWQYGNNPS---- 658
            :|:|:.|::.|..:..|.....|..:..|.  |....|: |.|       |.:|. |.|.:
Zfish   305 SNASLALQLSHTWLQRHILTDPASPVEFSG--VSSAPAFQPSPAMIKGLAETEWP-GRNQTLKHG 366

  Fly   659 PLTMSSDGHY-------------EISTRMENNDVYTSILRIAHLQHSDYGEYICRAVNPLDSIRA 710
            |:|...||.:             |::|:.|.| ...|:||:  |..:..||..|.|:
Zfish   367 PVTYYMDGAHTTRSMQACVRWFNEVATQHERN-AGGSVLRV--LLFNATGERDCAAM-------- 420

  Fly   711 PIRLQPKGSPEKPTNLKILEVGH-NYAVLNWTPGFNGGFMSTKYLVSYRRVATPREQTLSDCSGN 774
                           ||:|...| ::||  :.|.......|..  ...:......|..|:.|..|
Zfish   421 ---------------LKLLAPCHFDFAV--FCPNITEAIASCN--ADQQNFNVSVENMLTRCLDN 466

  Fly   775 GYIPSYQISSSSSNSNHEWIEFNCFKENP-CKL-----APL--DQH-QSYMFKVYALNSKGTSGY 830
                           ...|...|..:|.| .:|     .||  ::| .:.:|.......:..|..
Zfish   467 ---------------QQSWRVLNGHEEKPEAELLIGGGLPLVAERHGDTLVFPCILSALQWISQG 516

  Fly   831 SNEILATTKVSKIP--PPLHVSYDP-----NSHVL 858
            .:.:||......||  |.::....|     |.|||
Zfish   517 RDSVLADANKHTIPVKPSINAKAAPLREAQNIHVL 551

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653
		Ig	147..228	CDD:299845
		I-set	232..313	CDD:254352
		IGc2	250..302	CDD:197706
		IG_like	323..385	CDD:214653
		IGc2	330..385	CDD:197706
		Ig_2	416..501	CDD:290606
		IG_like	418..501	CDD:214653
		I-set	505..612	CDD:254352	2/5 (40%)
		Ig	526..611	CDD:143165	2/4 (50%)
		IG_like	633..715	CDD:214653	25/106 (24%)
		Ig	635..713	CDD:143165	24/102 (24%)
		FN3	720..838	CDD:238020	24/127 (19%)
fpgs	NP_998602.2	PLN02881	47..566	CDD:215476	63/295 (21%)
fpgs	NP_998602.2	Mur_ligase_C	356..437	CDD:280948	25/109 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0285
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900