DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment fred and Fpgs

DIOPT Version :9

Sequence 1:NP_608812.3 Gene:fred / 33613 FlyBaseID:FBgn0051774 Length:1447 Species:Drosophila melanogaster
Sequence 2:NP_572814.1 Gene:Fpgs / 32212 FlyBaseID:FBgn0030407 Length:572 Species:Drosophila melanogaster


Alignment Length:262 Identity:48/262 - (18%)
Similarity:79/262 - (30%) Gaps:94/262 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly   752 KYLVSYR-------RVATPREQTLSDCSGNGYIPSYQISSSSSNSNHEW--------IEFNCFKE 801
            ::|.::|       ||..|.:|::     ||...|..|..||.|:|.:.        .:.|..:.
  Fly    49 QHLAAFRSGVSLAERVLNPPQQSI-----NGNHVSGNIQCSSDNNNKDTNAAFELAIKQLNSLQS 108

  Fly   802 NPCKL-----------------------APLDQHQSYMFKVYALNSKGTSGYSNEILATTKVSKI 843
            |...:                       .||:..:...|    ::..||.|..:....|..:.: 
  Fly   109 NDAAIRNSMSNSRVDTKADTIKYLERSGLPLETVEQLSF----IHVAGTKGKGSTCALTESLLR- 168

  Fly   844 PPPLHVSYDPNSHVLGINVAATCLSLIAVVESLVTRDA-TVPMWEIVETLTLLPSGSETTFKEAI 907
            .......:..:.|:|..|      ..|.:...|:::|. |...|::...|..|.....       
  Fly   169 HQGFRTGFFSSPHILFTN------ERIRIDGQLLSKDKFTEQFWKVYNRLWDLREHDH------- 220

  Fly   908 INHVSRPAHYTTATTSGRS-----------LGVG-GGSH----------------LGEDRTMALA 944
                ..||::...|..|..           |.|| ||.|                ||.:.|..|.
  Fly   221 ----DMPAYFKFLTILGFHVFVAENVDVVVLEVGIGGEHDCTNIVRNVRTVGITSLGLEHTELLG 281

  Fly   945 ET 946
            .|
  Fly   282 RT 283

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fredNP_608812.3 Ig 29..126 CDD:299845
IG_like 141..228 CDD:214653
Ig 147..228 CDD:299845
I-set 232..313 CDD:254352
IGc2 250..302 CDD:197706
IG_like 323..385 CDD:214653
IGc2 330..385 CDD:197706
Ig_2 416..501 CDD:290606
IG_like 418..501 CDD:214653
I-set 505..612 CDD:254352
Ig 526..611 CDD:143165
IG_like 633..715 CDD:214653
Ig 635..713 CDD:143165
FN3 720..838 CDD:238020 22/123 (18%)
FpgsNP_572814.1 PLN02881 90..554 CDD:215476 34/216 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0285
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.900

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