DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and CG30350

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	NP_724715.1	Gene:	CG30350 / 246556	FlyBaseID:	FBgn0050350	Length:	369	Species:	Drosophila melanogaster

Alignment Length:	204	Identity:	37/204 - (18%)
Similarity:	74/204 - (36%)	Gaps:	69/204 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   803 PCKLAPLDQ----HQSYMFKVYALNSKGTSGYSNEIL----ATTKVS--KIPPPLHVSYD----- 852
            |..|..|::    ::.:..::..:||:..||.|::.:    ::|.|:  ::||.....|:
  Fly   135 PMALLTLEKLERDNRDFGRRILEVNSEVDSGLSDKRMREGRSSTPVAPLELPPQAMAKYEAFNIP 199

  Fly   853 -PNS--------------------------HVLGINVAATCLSLIAVVESLVTRDATVPM----- 885
             |.|                          .|:.:...|..|.::.:::|.:....:..|
  Fly   200 LPKSDAELRRLFRPRIYFDLYLKDARPLGRFVVQLYTEAAPLVVLQLIKSCMCNQHSKFMVKRLF 264

  Fly   886 ---WEIVETLTLLPSGS----ETTFKEAIINH-------------VSRPAHYTTATTSGRSLGVG 930
               |  :||..:|.|.|    ...:...:|:|             |:...|:.:...|.:.|.|.
  Fly   265 PNLW--LETDLMLSSDSLLHQPLEYDAKVIDHGASSYVLSFSKAYVTGFTHHLSFAISFKPLTVV 327

  Fly   931 GGSHLGEDR 939
            .||.:|..|
  Fly   328 NGSRVGFGR 336

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653
		Ig	147..228	CDD:299845
		I-set	232..313	CDD:254352
		IGc2	250..302	CDD:197706
		IG_like	323..385	CDD:214653
		IGc2	330..385	CDD:197706
		Ig_2	416..501	CDD:290606
		IG_like	418..501	CDD:214653
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020	8/42 (19%)
CG30350	NP_724715.1	KIAA1430	60..155	CDD:290590	3/19 (16%)
CG30350	NP_724715.1	cyclophilin	212..369	CDD:294131	22/127 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3515
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900