DRSC/TRiP Functional Genomics Resources

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Protein Alignment fred and LOC1279073

DIOPT Version :10

Sequence 1:NP_608812.3 Gene:fred / 33613 FlyBaseID:FBgn0051774 Length:1447 Species:Drosophila melanogaster
Sequence 2:XP_061518126.1 Gene:LOC1279073 / 1279073 VectorBaseID:AGAMI1_008509 Length:982 Species:Anopheles gambiae


Alignment Length:1281 Identity:241/1281 - (18%)
Similarity:383/1281 - (29%) Gaps:504/1281 - (39%)


- Green bases have known domain annotations that are detailed below.


  Fly   142 ATEEKPLELTCSSIGGSPDP--MITWYREGSTVPLQSYALKG---------------GSKNHYTN 189
            |.|.:.:.|.|.....|.|.  |:.|:::.:.:||.|:.::|               |.:.|:..
Mosquito    51 AVEGRKISLPCPLSAPSRDKVYMVLWFKDDAGIPLYSFDVRGKPLQQARHWSAPEIFGPRAHFNT 115

  Fly   190 ----ATLQIVPRRADDGAKYKCVVWNRAMPEGHMLETSVTLNVNYYPRVEVGPQNPL-------- 242
                |||.|...|..|...|:|.|..|         ||.|.:..|...:.:.|::|:        
Mosquito   116 DTDPATLDIQDVRRHDEGVYRCRVDFR---------TSQTQSFRYNLSIIILPEHPVVLSQWGQQ 171

  Fly   243 --------KVERDHVAKLDCR-VDAKPMVSNVRWSRNG-----QYVSATPTHTIYRVNRHHAGK- 292
                    |.|.|.:. |.|| |..:|..| |:|..||     ||             .|::|. 
Mosquito   172 LNSSKLGPKEEGDDIV-LTCRVVGGRPQPS-VKWLINGILVDEQY-------------EHNSGDV 221

  Fly   293 ------------------YTCSADNG-LGKTGEKDIVLD---------VLYPPIVFIESKTHEAE 329
                              :||.|.|. |.:..|...|||         ::.|....:..:.:|  
Mosquito   222 IENRLLWPAIQRSDLNSIFTCQATNTLLVEPKESSFVLDLHLKPLSVKIMNPQTPLVADRRYE-- 284

  Fly   330 EGETVLIRC-NVTANPSPINVEWLKEGAPDFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSSK 393
                  |.| :|.:.|:.| :.|.| |....|...|.:...:.|:|                   
Mosquito   285 ------ISCESVGSRPNAI-ITWYK-GKRQLRRAKEEILNNTTRSE------------------- 322

  Fly   394 RVEGVGNSTVALLVRHRPGQAYITPNKPVVHVGNGVTLTCSANPPGWPVPQYRWFRDMDGDIGNT 458
                               .:::...:     .:|..:||.|..|                    
Mosquito   323 -------------------LSFVPTTE-----DDGKQITCRAENP-------------------- 343

  Fly   459 QKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIGKIATIILEVHQPPQFLAKLQQHMTRRVGDV- 522
                                        |..|:....:..:||..||  :..|:...|....|: 
Mosquito   344 ----------------------------NVTGLFLETSWKIEVVYPP--IVSLRLGSTLSADDIK 378

  Fly   523 ---DYAVTCSAKGKPT-PQIRWIKDGTEILPTRKMFDIRTTPTDAGGGVVAVQSILRFRGKARPN 583
               |....|..:..|. .::.|:.||..|........||:..:      :.:|.:.|        
Mosquito   379 EGDDVYFECHVQANPPWRKLHWLHDGVMITHNATARVIRSNQS------LVLQKVTR-------- 429

  Fly   584 GNQLLPNDRGLYTCLYEN-DVNSANSSMHLRIEHEP-------IVIHQYNKVAYDLRESAEVVCR 640
                  |..|.|:|...| :..:.::.:.||:::.|       |::..:..      ||.::.|.
Mosquito   430 ------NSSGNYSCSAINAEGETVSNQLALRVKYAPVCATDRIIIVGAFRS------ESLQIPCE 482

  Fly   641 VQAYPKP-EFQWQYGNNPSPLTMSSDGHYEISTRMENNDVYTSILRIAHLQHSDYGEYICRAVNP 704
            |.|.|.| :|.|::.|:...|.:..:.:      ::|..:  |:|....:...|||...|...|.
Mosquito   483 VHADPPPRQFNWKFNNSGETLKIGKERY------VKNGSI--SLLNYIPVSDQDYGTLTCWGQNE 539

  Fly   705 LDSIRAPIRLQP--KGSPEKPTNLKILEVGHNYAVLNWTPGFNGGFMSTKYL--VSYR------R 759
            :.:...|...|.  .|.|....|..|.....:...:...||::||......|  :|.|      .
Mosquito   540 VGTQDWPCFFQVVLAGLPSAVKNCSINNQTQHSVEVQCLPGYDGGLPQIFILEVISSRTGRVRYN 604

  Fly   760 VATPREQTLSDCSGNGYIPSYQISSSSSNSNHEWIEFNCFKENPCKLAPLDQHQSYMFKVYALNS 824
            |..|.|            |.:.:.|..:..::.....:...:||.|..           :||:|.
Mosquito   605 VTNPDE------------PYFLVESLENLIHYGGAYDDIGDDNPLKAI-----------IYAVNQ 646

  Fly   825 KG------------TSGYSNE--ILATTKVSKIPPPLHVSYDPNSHVLGINVAATCLSLIAVVES 875
            ||            .|...|.  :|.:..:..|.|.|          .|:.:....|..:..|. 
Mosquito   647 KGRSQGIVVKDFYLESAVENRAGVLTSNSLDSISPIL----------FGVLLTLLVLCFVIFVR- 700

  Fly   876 LVTRDATVPMWEIVETLTLLPSGSETTFKEAIINHVSRPAHYTTATTSGRSLGVGGGSHLGEDRT 940
                                            :.::...|..||.|.....|  ...|..|.::.
Mosquito   701 --------------------------------VYYIKATATSTTITNVSNDL--VSNSKQGNNKQ 731

  Fly   941 MALAETAGPGPVVRVKLCLRSNHEHCGAYANAEIGKSYMPHKSSMTTSALVAIIIASLSFVVFLG 1005
            ..||:                                    ||:                     
Mosquito   732 DTLAK------------------------------------KSA--------------------- 739

  Fly  1006 LLYAFCHCRRKHAAKKESSSVGGGVGGGNANATANPGSTGAKEYDLDLDA-SRRPSL-SQDPQQS 1068
                      |.:.:.:..:.||||||     ....|.||. ...|.:|. ||...| :.|..:.
Mosquito   740 ----------KQSPRWQQGNSGGGVGG-----VGGYGGTGT-GCGLIVDGRSRDEKLGAPDGMED 788

  Fly  1069 QQQPPPPPPYYPTGTLDSKDIG-------NGN---------------------GGMELTLTA--- 1102
            ::.|...|..:.... ||:.:.       |||                     |.:..|.||   
Mosquito   789 ERDPDVIPAQFAVSN-DSESVSFNSSKWPNGNFYDRYPNHDIRPSELLLPSAAGTLGPTATATVT 852

  Fly  1103 ---LHDPDEQLNMQQQQHHSNHGQYQQPKAILGIYGGVAGSGGNNSGGQHPHSNGYGYHVTSAIG 1164
               ||.     |:.|.......|.|..|..:|      .|.||   |...|.:.|          
Mosquito   853 TNQLHP-----NVNQPGDSIKLGPYYTPSGLL------TGGGG---GPTAPGTTG---------- 893

  Fly  1165 VDSDSYQVLPSVANSAAGSHGHGSGHGHGLGAGESGPLEATPPTCNISGGSSSNSGINPMQQQHS 1229
                  ..|.....|.||||...||...|:|.|  |||..          ||:.|| ..:...|.
Mosquito   894 ------TTLAGAYLSPAGSHPLDSGGLDGVGVG--GPLMY----------SSAGSG-QTLVGNHH 939

  Fly  1230 ARANLTNQPTIATASST------NNYNNHLNN-TNIAHTTNNTNNC 1268
            ..:.|.|    .||.||      |:|:.:::. .|:..||....:|
Mosquito   940 QSSLLPN----GTAGSTGTGVNPNDYDINVHTIKNMLMTTRVPESC 981

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
fredNP_608812.3 Ig 132..228 CDD:472250 27/106 (25%)
Ig strand B 148..152 CDD:409353 1/3 (33%)
Ig strand C 162..166 CDD:409353 1/3 (33%)
Ig strand E 190..194 CDD:409353 3/3 (100%)
Ig strand F 204..209 CDD:409353 2/4 (50%)
Ig strand G 221..224 CDD:409353 1/2 (50%)
Ig 238..313 CDD:472250 28/125 (22%)
Ig strand B 250..254 CDD:409353 1/3 (33%)
Ig strand C 264..268 CDD:409353 1/3 (33%)
Ig strand E 278..282 CDD:409353 0/3 (0%)
Ig strand F 292..297 CDD:409353 2/23 (9%)
Ig strand G 306..309 CDD:409353 1/2 (50%)
Ig_3 316..385 CDD:464046 14/69 (20%)
Ig_2 416..501 CDD:464026 7/84 (8%)
Ig 523..614 CDD:472250 17/92 (18%)
Ig strand B 524..528 CDD:409568 0/3 (0%)
Ig strand C 537..541 CDD:409568 0/3 (0%)
Ig strand E 566..570 CDD:409568 0/3 (0%)
Ig strand F 594..599 CDD:409568 2/4 (50%)
Ig strand G 607..610 CDD:409568 0/2 (0%)
Ig_3 618..703 CDD:464046 20/92 (22%)
FN3 720..838 CDD:238020 26/139 (19%)
LOC1279073XP_061518126.1 None

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