DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC110439988

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021333834.1	Gene:	LOC110439988 / 110439988	-ID:	-	Length:	213	Species:	Danio rerio

Alignment Length:	226	Identity:	48/226 - (21%)
Similarity:	74/226 - (32%)	Gaps:	78/226 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   201 DGAKYKCVVWNRAMPEGHMLETSVTLNVN--YYPRVEV--GPQNPLKVERDHVAKLDCRVDAKPM 261
            ||.:.....|::  .:|..:.....|:|:  |..|::.  ..|....|...||.|.|........
Zfish    40 DGLQIMRAFWHK--DQGIQVVEPPDLSVDSEYSQRLQYLGDKQQNHTVRLSHVTKKDEHEYYFRF 102

  Fly   262 VSNVRWSRNGQYVSATPTHTIYRVNRHHAGKYTCSADNGLGKTGEKDIVLDVLYPPIVFIESKTH 326
            ::||             ||..:                    ||...::|.|....:...|..|
Zfish   103 ITNV-------------THEKW--------------------TGRPGVILSVTDLQLESPERVT- 133

  Fly   327 EAEEGETVLI----RCNVTANPSPINVEWLKEGAPDFRYTGELLTLGSVRAEHAGNYICRSVNIM 387
               ||::|.:    .||:|..|:.|   |.: .:......|:.|.:.||....||:|.|
Zfish   134 ---EGDSVRLTCRSSCNLTDTPTFI---WYR-NSHTLTNIGDELNIRSVSRTEAGHYSC------ 185

  Fly   388 QPFSSKRVEGVGNSTVALLVRHRPGQAYITP 418
                     ||            .||.||:|
Zfish   186 ---------GV------------QGQTYISP 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653	5/26 (19%)
		Ig	147..228	CDD:299845	5/26 (19%)
		I-set	232..313	CDD:254352	14/82 (17%)
		IGc2	250..302	CDD:197706	6/51 (12%)
		IG_like	323..385	CDD:214653	18/65 (28%)
		IGc2	330..385	CDD:197706	17/58 (29%)
		Ig_2	416..501	CDD:290606	2/3 (67%)
		IG_like	418..501	CDD:214653	1/1 (100%)
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC110439988	XP_021333834.1	Ig	13..102	CDD:325142	14/63 (22%)
LOC110439988	XP_021333834.1	IGc2	134..185	CDD:197706	16/54 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010