DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC110439914

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021333328.1	Gene:	LOC110439914 / 110439914	-ID:	-	Length:	206	Species:	Danio rerio

Alignment Length:	273	Identity:	55/273 - (20%)
Similarity:	92/273 - (33%)	Gaps:	94/273 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   435 ANPPGWPVPQYRWFRDMDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIGKIATIIL 499
            :|||..   .:.||::      |....:..|..:|..::     |:::|.|.|..|..:...:.:
Zfish     6 SNPPAL---SFSWFKE------NQSSAVGSGQSFSAVQS-----GRFYCEAHNPHGAQRSDAVTV 56

  Fly   500 EVHQPPQFLAKLQQHMTRRVGDVDYAVTCSAKGKPTPQIRWIKDGTEILPTRKMFDIRTTPTDAG 564
            .||          :|..|.:     .:|.::.|.....|..|
Zfish    57 TVH----------EHAERNI-----IITATSVGVLIIFIIII----------------------- 83

  Fly   565 GGVVAVQSILRFRGKARPNGNQLLPNDRGLY------TCLYENDVNSANSSMHLRIEHEPIVIHQ 623
              |:.|..|::.:...:..|..:..||  ||      |.:|:|.|          .:..|:....
Zfish    84 --VIIVLFIIKKQRSVKSEGLIVTQND--LYSDVPQKTQVYDNPV----------CDPGPVDEAP 134

  Fly   624 YNKVAYDLRESAEVVCR---------VQAY---PK----PEFQWQYGNNPSPLTMSSDGHYEIST 672
            |..|  :.|.|||  ||         ||.:   ||    .|.|.|..|  :|:......|.:.:.
Zfish   135 YETV--NPRISAE--CRGAEEIQYATVQYHKNTPKKKEEEEEQRQCDN--TPVQQPDQDHRQENV 193

  Fly   673 RMENNDVYTSILR 685
            ......|..|:|:
Zfish   194 ETVEESVIYSMLK 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653
		Ig	147..228	CDD:299845
		I-set	232..313	CDD:254352
		IGc2	250..302	CDD:197706
		IG_like	323..385	CDD:214653
		IGc2	330..385	CDD:197706
		Ig_2	416..501	CDD:290606	13/65 (20%)
		IG_like	418..501	CDD:214653	13/65 (20%)
		I-set	505..612	CDD:254352	18/112 (16%)
		Ig	526..611	CDD:143165	16/90 (18%)
		IG_like	633..715	CDD:214653	18/69 (26%)
		Ig	635..713	CDD:143165	17/67 (25%)
		FN3	720..838	CDD:238020
LOC110439914	XP_021333328.1	Ig_2	<2..58	CDD:316418	13/65 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010