DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC110438280

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021330158.1	Gene:	LOC110438280 / 110438280	-ID:	-	Length:	235	Species:	Danio rerio

Alignment Length:	189	Identity:	38/189 - (20%)
Similarity:	70/189 - (37%)	Gaps:	36/189 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   225 TLNVNYYPRVEVGPQNPLKVERDHVAKLDCRVDAKPMVSNVRWSRNGQY---VSATPTHTIYRVN 286
            |:...::..::.|....|:.|.....:::. |:.|..:..::.|.:|:|   :....|...|
Zfish    40 TVKKTFWHYIQTGDFRDLREEHQFAGRVEF-VENKLRIKELKISDSGEYRFRIITDKTKRTY--- 100

  Fly   287 RHHAGKYTCSADNGLGKTGEKDIVLDVLYPPIVFIESKTHEAEEGETVLIRCNVTANPSPINVE- 350
                             :|...::|:|....::   ::.|...|||.|::.|:.....|..:..
Zfish   101 -----------------SGSPGVILNVTDTQVI---NRPHTVSEGEKVILSCSTKCTLSNKHTYI 145

  Fly   351 WLKEG--APDFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSSKRVEGVGNSTVALLV 407
            |.|.|  ..|.......|.|.||..|....:.|.   :.:...|   ..|.:.||.|||
Zfish   146 WYKNGRQVTDGFTKDNKLYLDSVSKEERQEFSCA---VGEAVDS---TAVSHYTVTLLV 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653	1/2 (50%)
		Ig	147..228	CDD:299845	1/2 (50%)
		I-set	232..313	CDD:254352	12/83 (14%)
		IGc2	250..302	CDD:197706	7/54 (13%)
		IG_like	323..385	CDD:214653	17/64 (27%)
		IGc2	330..385	CDD:197706	16/57 (28%)
		Ig_2	416..501	CDD:290606
		IG_like	418..501	CDD:214653
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC110438280	XP_021330158.1	IG_like	16..>88	CDD:214653	8/48 (17%)
LOC110438280	XP_021330158.1	Ig_3	114..178	CDD:316449	16/66 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010