DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC103909460

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_009293728.2	Gene:	LOC103909460 / 103909460	-ID:	-	Length:	286	Species:	Danio rerio

Alignment Length:	301	Identity:	67/301 - (22%)
Similarity:	105/301 - (34%)	Gaps:	75/301 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   228 VNYYPRVEVGPQNPLKVERDHVAKLDCR-VDAKP--MVSNVRWSR-----NGQYVSATPTHTIYR 284
            |||.|:.....||       ....:.|. :...|  .:..|.|::     :|:..:....::.|.
Zfish    10 VNYSPKQYCALQN-------STMTISCTFIYPTPGFQIMKVFWNKDQEKYDGENFTDLSNYSEYS 67

  Fly   285 VNRHHAGKYTCSADNGLGKTGEKD-------IVLDVLYPPIVFIE-----------SKTHEAEEG 331
            ....:.|....:....|....|||       ...:|.:..::.|.           .......||
Zfish    68 QRLQYLGDKQQNCTVRLSHVTEKDEHDYYFRFTTNVTFGKVIGIPGVRLSVTDLQLESPERVTEG 132

  Fly   332 ETVLI----RCNVTANPSPINVEWLKEGAPDFRYTGELLTLGSVRAEHAGNYICRSVNIMQPFSS 392
            ::|.:    .||:|..|:.|   |.: .:......|:.|.:.||....||.|.|
Zfish   133 DSVRLTCRSSCNLTDTPTFI---WYR-NSHTLTNIGDELNIRSVSRREAGRYSC----------- 182

  Fly   393 KRVEGVGNST-----VALLVRHRPGQAYITPNKPVVHVGNGVTLTCS--ANPPGWPVPQYRWFRD 450
                ||...|     |.|.:.:.|....|:....|:..|:.|.|.||  ||||.    :..|::
Zfish   183 ----GVQGQTYISPAVYLNITYAPDTPVISNRSAVIMEGDSVILNCSSNANPPA----EINWYK- 238

  Fly   451 MDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGI 491
                 |.|.  |..|..::|.|......|:|.|.|.||.|:
Zfish   239 -----GKTS--LNSGRIFNISKISSDDSGEYKCRARNEHGV 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653	67/301 (22%)
		Ig	147..228	CDD:299845	67/301 (22%)
		I-set	232..313	CDD:254352	14/95 (15%)
		IGc2	250..302	CDD:197706	7/59 (12%)
		IG_like	323..385	CDD:214653	17/65 (26%)
		IGc2	330..385	CDD:197706	17/58 (29%)
		Ig_2	416..501	CDD:290606	25/78 (32%)
		IG_like	418..501	CDD:214653	24/76 (32%)
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC103909460	XP_009293728.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010