DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fred and LOC101883960

DIOPT Version :9

Sequence 1:	NP_608812.3	Gene:	fred / 33613	FlyBaseID:	FBgn0051774	Length:	1447	Species:	Drosophila melanogaster
Sequence 2:	XP_021333851.1	Gene:	LOC101883960 / 101883960	-ID:	-	Length:	470	Species:	Danio rerio

Alignment Length:	394	Identity:	85/394 - (21%)
Similarity:	155/394 - (39%)	Gaps:	83/394 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   152 CSSIGGSPDPMITWYREGSTVPLQSYALKG--------------------------GSKNHYTNA 190
            |..:..:|.|.|...| ||||....:...|                          .|.|...:.
Zfish    24 CWYVNYTPSPYICALR-GSTVSTTCFYPTGYQIEEVFWTTSKNAKLSGPEISQWDCSSGNQENSY 87

  Fly   191 TLQIVPRRADDGAKYKCVV---WNRAMPEGHMLETSVTLNVNYYPRVEVGPQNPLKVERDHVAKL 252
            .|.|.....:|...|.|..   |:........:..|||         ::..::|.:|......:|
Zfish    88 CLHISEVTQEDSDNYYCTFVSSWDNIFSATQGVRLSVT---------DLQVESPERVTEGDSVRL 143

  Fly   253 DCRVDAKPMVSNV-RWSRNGQYVS--ATPTHTIY-RVNRHHAGKYTCSADNGLGKTGE----KDI 309
            .||...|.:.:.: .|.||.:.::  :.....:| .|:|.|||.|:|      |..|:    ..:
Zfish   144 TCRSSCKLIDTPIFIWYRNSKPLTQGSIQNKLVYSSVSRGHAGGYSC------GVQGQDYISPTV 202

  Fly   310 VLDVLYPP--IVFIESKTHEAEEGETVLIRCNVTANPSPINVEWLKEGAPDFRYTGELLTLGSVR 372
            .|:|.|.|  ::...|::....||::|.:.|:..:|| |..:.|.|  ..::..:|.:.::..::
Zfish   203 YLNVRYKPWSVLVSISESDVITEGDSVTLSCSSDSNP-PAALLWYK--GVEYIKSGRIFSILMIK 264

  Fly   373 AEHAGNYICRSVNIMQPFSSKRVEGVGNSTVALLVRHRPGQAYIT-PNKPVVHVGNGVTLTC--S 434
            ::.:|.|.||::|   ....|.     :..|.|.|::.|....:: ....|:..|:.|:|.|  .
Zfish   265 SDDSGEYKCRAIN---EHGEKY-----SDPVTLDVQYPPRSVSVSISGSAVIMSGDSVSLMCISD 321

  Fly   435 ANPPGWPVPQYRWFRDMDGDIGNTQKILAQGPQYSIPKAHLGSEGKYHCHAVNELGIGKIATIIL 499
            :|||..   .:.||.:      |....:..|..:|..::     |:::|.|.|..|..:...:.:
Zfish   322 SNPPAL---SFSWFEE------NQSSAVGSGQSFSAVQS-----GRFYCEAHNPHGAQRSDAVTV 372

  Fly   500 EVHQ 503
            .|.|
Zfish   373 TVQQ 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fred	NP_608812.3	Ig	29..126	CDD:299845
		IG_like	141..228	CDD:214653	21/104 (20%)
		Ig	147..228	CDD:299845	21/104 (20%)
		I-set	232..313	CDD:254352	20/88 (23%)
		IGc2	250..302	CDD:197706	15/55 (27%)
		IG_like	323..385	CDD:214653	15/61 (25%)
		IGc2	330..385	CDD:197706	14/54 (26%)
		Ig_2	416..501	CDD:290606	18/87 (21%)
		IG_like	418..501	CDD:214653	18/84 (21%)
		I-set	505..612	CDD:254352
		Ig	526..611	CDD:143165
		IG_like	633..715	CDD:214653
		Ig	635..713	CDD:143165
		FN3	720..838	CDD:238020
LOC101883960	XP_021333851.1	IG	37..124	CDD:214652	14/87 (16%)
		Ig_3	131..190	CDD:316449	16/58 (28%)
		Ig_2	214..291	CDD:316418	19/87 (22%)
		Ig_2	305..374	CDD:316418	18/82 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D35531at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010